Erectile and ejaculatory conditions +obstetrics Flashcards
what type of drugs can be used for erectile dysfunction?
-phosphodiesterase type-5-inhibitors
-prostaglandin analogue
what are some examples of phosphodiesterase type-5 inhibitors?
-sildenafil (1hour before sex)
-tadalafin (30 mins before sex
-vardenafil (25-60 mins before sex)
-avanafil (30mins before sex)
what is an example of a prostaglandin analogue?
-alprostadil (not given orally)
-seek urgent medical help for prolonged erection lasting more than 4 hrs (priapism)
how does a phosphodiesterase type-5 inhibitors?
increases blood flow to penis. delayed effect with food
what are some side effects of phosphodiesterase type-5 inhibitors?
-vasodilator= hypotension, flushing, headaches, migraine, dyspepsia, nasal congestion, palpitations, tachycardia
when are phosphodiesterase type-5 inhibitors contraindicated?
-myocardial infarction, unstable angina, recent stroke, hypotension, systolic <90mmHg or taking nitrates due to reduced blood perfusion
what type of interactions can occur with phosphodiesterase type-5 inhibitors?
-nitrates, alpha-blockers (once stabilised, then initiate), CCB, nicorandil
what drugs are used for an abortion?
-gemeprost (0prostaglandin analogue)
-mifespristone (anti-progestogen)
-misoprostol (prostaglandin analogue)
what drugs are used to induce or augment labour?
-dinoprostone (naturally occurring prostaglandin )
-misoprostol
-oxytocin (naturally occurring hormone)
what drugs are used to prevent and treat bleeding labour/ abortion/ miscarriage?
-carbetocin
-carboprost
-ergometrine
-misoprostol
-oxytocin
what type of drug are used for ectopic pregnancy ?
-methorexate
what type of drugs are used in premature labour?
-salbutamol/terbutaline
-atosiban
-indometacin
nifedipine
