Equipment #1 Flashcards

1
Q

What is the ideal gas Law Triangle,

A

Can these guys possibly be violinests

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2
Q

What is the Combinded Gas Law?

Calculate Kelivn.

A

C=K-273

C + 273 = Kelvin

F=(C*9/5)+32

C= (F-32)*5/9

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3
Q

What is Vapor pressure?

What are the Gas vapor pressures?

A

KNow that N2O is liquid with 745psi in has on top

The point at which the molecules going into the gas phase equal the molecules in the liquid phase, at a particular pressure,

Vapor pressure is a funtion of temperature, vapor pressure will not change with a change in altitude.

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4
Q

What effects MAC

A

MAC- Higher in -Infants, hyperthermia, alcoholism

Lower- hypothermia, hypotension, pregancy,

Non Factors- Gender, hight, weight.

Declines 6% per decade

Vapor pressure is temp dependent

At a higher elevation it will boil more easily

A Tec-6 Vaporizer calibrated in LA, will result in greater Volatile delivered in Colorado

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5
Q

MAC and Elevation, for volatile agents

A

For Des you will need to dial a higher concernation at high elevation to attain the same clinical effect.

For Iso you don’t, however the partial pressure of iso will be diffrent, but the altitue will effect it appropriatly.

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6
Q

Calculate the % and Pressures

ATM

CAlculate Maxiumum agent concentration

Calculate Concentration in mmHg

A
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7
Q
A
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8
Q

Graham’s Law

A

Graham’s Law
– The rate of diffusion is inversely proportional
to the square root of the molecular weight
• Large molecules diffuse more slowly

Heilium baloon story, over time the heilium molecules will make it outside the ballon

FYI (Graham’s law and Ficks law both apply to N20) b/c the both explain the diffusion of N20

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9
Q

E-cylinders,

What are the volumes?

Whater the Features?

A

• E-cylinders:
Measures 2’ x 4”
Internal volume of 5000 cc
Specific wall thickness for the gas to be stored

• Features:
Pin Index Safety System
Pressure relief system
Yoke assembly

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10
Q

O2 Cylinder

What is the critical temp of O2?

What Law?

Cull cylinder? Liters/psi

When changed?

A

Oxygen Cylinder
• Must be stored as a gas
– critical temperature is
-
118 C
• Follows Boyle’s Law
• Full cylinder contains 660 liters
• Full cylinder at 2000 psi
• Tank pressure correlates linearly with tank
volume
• Tank should be changed if < 1000 psi

Change anything if it is below half

Most questions are about O2 tank

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11
Q

Nitrous Cylinder-

critical temp

what law?

pressure gauage?

liters?

PSI?

A

Nitrous Oxide Cylinder
• 90-95% filled with liquid N2O
• Critical temperature is 36.5 C
• Does not follow Boyle’s law until all liquid
in the cylinder is consumed
• Pressure gauge does not correlate with
volume until all liquid is consumed
• Full E-cylinder contains 1590 liters
• Full E-cylinder pressure = 750 psi

When gauage moves you are almot empy

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12
Q

The anesthesia Machine Basic Layout

A
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13
Q

Anestheisa Machine componets

A

Machine Components
• Oxygen supplies
• Nitrous and other gas supplies
• Gauges
• Regulators
• Fail-Safe Valve, Oxygen supply alarm
• Flow meters
• Oxygen ratio proportioning systems
• Flush valve and gas outlet

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14
Q

Oxygen Supplies

A

Wall supply at 40-60 psi uses labeling, color coding and DISS
• Tank supply
from E-cylinder on yokes
• Oxygen flows to 5 places:
Flush valve
Oxygen supply failure alarm
Fail-Safe valve
Flow meters
Pneumatically powered devices e.g. ventilator

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15
Q

Nitrous & Other Gas Supplies

A
  • Nitrous and other gases also supplied by

wall outlets or E-cylinders
Also uses labeling, color coding and DISS

• Nitrous oxide flow is only to the flow
meters, through the fail-safe valve
• Other gases, e.g. air, follow similar
pathway, but may not be involved in the
fail-safe valve

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16
Q

What gauges are used?

What principle used?

A

Gauges
• Uses the Bourden principle*******
curved metallic tube that straightens with increased pressure
• Designed to read 33% higher than
maximum working pressure
• Heavy metal case and plate glass front in
case of Bourden tube rupture

**-In every text boo****

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17
Q

What do Regulators do?

A

Converts variable high pressure to
constant low pressure

Machines have 2 nd stage regulator after inlet of the
pipelines to further reduce pressure and maintain a constant pressure even if wall outlet pressure varies
• E-cylinder regulators designed to deliver
less pressure than the wall outlet
If tanks are accidentally left on, wall supply is used preferentially

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18
Q

Fail-Safe Valve,

O2 Alarm

A

• Fail-Safe (Oxygen Pressure Cutoff) Valve
shuts off other gas flow if O 2 pressure falls below 25 psi d_oes not prevent delivery of hypoxic mixtures_

• Oxygen Supply Failure Alarm
oxygen fills a cylinder when the machine is on, if pressure drops suddenly O2 will come out of the cylinder and slowly pass through a whistle, this will alert you to loss of pressure. If O2 is lost slowely it may not alarm

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19
Q

Flow Meters

diameter?

Flow rate?

Effect of changing barometric pressure,

A

Flow Meters
• Tapered glass tubes larger at top this allows constant pressure with variable flow
• High flow rate produces turbulent flow density of gas is the major flow rate factor CO 2 and N 2 O have similar densities
• Low flow rate
produces laminar flow viscosity of gas is the major flow rate factor O 2 and Helium have similar viscosities
Effect of changing barometric pressure
decreased pressure = rotameter too low, underestimating flow
increased pressure = rotameter too high, overestimating flow

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20
Q

Oxygen Proportioning Systems

A

• Machines are equipped with devices to
prevent delivery of FiO 2 < 25%

• Proportioning systems only linked to N 2 O
if other gases are used, hypoxic gas mixtures could be
delivered

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21
Q

Flush Valve & Gas Outlet

Flush= what psi and liters?

common gas outlet?- what size?,

A

• Flush valve bypasses on-off switch
Delivers oxygen at 40-60 psi
risk of barotrauma under certain conditions
• Estimated rate of delivery: 30-70 Liters/Min
• Common gas outlet
15 mm size; different from breathing circuit or scavenger
Often equipped with check valve to prevent retrograde
gas flow

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22
Q

Explain Vaporizers and varible bypass

A

Flow does not effect concentration, they are flow independent.

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23
Q

VAporizer output regulation

A

Using Dalton’s Law, saturated vapor pressures are:
desflurane = 91%
isoflurane = 31%

sevoflurane = 24%

(The saturated VP is the VP/ ATM 760)

Varible Bypass vaporizers compensate for temp, iso from 20C to 35C will nearly double its VP,// But the vaporizer will compenssate for ambient temp

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24
Q

Vaporizer Characteristics

A
  1. Variable bypass allows a fixed
    concentration regardless of the flow
  2. Vaporizers are vapor pressure specific –
    only agents with identical vapor pressures can be
    interchanged
  3. Vaporizers must have a mechanism to
    compensate for temperature variation
  4. Vaporizers must have an efficient heat
    transfer system
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25
Vaporizer Use Variables What much gas per ml? How long will 100ml of sevo last when 3ml/min at 2% BOARDS
• Most volatile agents produce about **200 cc** of gas for each cc of liquid • How long will 100 cc of sevoflurane last when given at 3L/min at 2%? 3000 cc x .02 = 60 cc/minute of sevoflurane used 60cc / 200 cc per 1 cc liquid = 0.3 cc liquid used each minute 100 cc / 0.3 cc/min = 333 minutes **100 cc of sevoflurane will last 333 minutes at 3L/m at 2**%
26
Barometric Pressure Effects A decrease is barometric pressure casuses whtat to the vaorizer output? vise versa?
• Decreases in barometric pressure cause an increase in vaporizer output • Conversely, increases in barometric pressure cause a fall in vaporizer output
27
Des Vaporizer What is the des vaporpressure when delivered? What happens with N20?
• Desflurane vaporizer heats the agent to 39º C • This increases the vapor pressure to 1500 • Pressure sensors determine the fresh gas flow rate and the output is calculated • Desflurane is then introduced into the fresh gas flow as a gas • **Output decreases when N2O introduced ??? (canot find why- Maybe ask instructors))**
28
Circle System Componets
• CO 2 absorber • APL “Pop-off” • Unidirectional valves • Reservoir bag • Circuit hoses • Fresh gas supply
29
What are the Mapleson systems?
You should appreciate that if you need to ventilate an apneic patient with one of the previously described systems, all six will work. These six are the Mapleson A, MaplesonB, Mapleson C, Mapleson D, Mapleson E, Mapleson F, and the Bain circuit (a modification of Mapleson D). During Controlled ventilation: **D F E \> B C \> A.**
30
Explain the CO2 absorber and all questions assosciated with it
Reactions of CO2 in Soda Lime 1. CO2 + H2O → H2CO3 2. H2CO3 + 2NaOH (2KOH) → Na2CO3 (K2CO3) + 2H2O + heat 3. Na2CO3 (K2CO3) + Ca(OH)2 → CaCO3 + NaOH (2KOH) Composition and Size of Soda Lime Granules a. 94% **Ca**(OH)2 5% **Na**OH 1% **K**OH • Irregular granules, **4-8 mesh** – provides maximal surface area with minimal airway resistance Canister 50% airspace, 50% absorbent Indicator (**ethyl violet**) indicates exhaustion 1000 gm canister can absorb 200 L of CO 2
31
APL & Unidirectional Valves
• APL vents excess gas to scavenger • U_nidirectional valves_ Disk valves Prevent rebreathing of CO 2
32
What is the dead space in the ventilated patient?
**Treachea,** **ETT** **MASk** **LMA** **Y connector** **Any other place has both in and out air**
33
Reservoir Bag & Circuit Hoses How big should the bag be?
• Reservoir Bag Serves as reservoir to buffer high inspiratory & exhaled gas flows Serves as a shock buffer Serves as a means of giving positive pressure **_Volume of the BAG should exceed inspiratory capacity_** The bag will maintain a pressure of 40 even as it gets bigger. • Circuit hoses 22mm fitting – different from gas outlet or scavenger Compliance is about 3cc/cmH 2 O/meter Large diameter offers almost no resistance Dead space only in areas of bi-directional flow – **Dead space ends at the Y-piece of the circuit**
34
Mapelson Circuits
35
Compare Mapelson A to Mapelson D Circutis controlled vs. Spontaneous?
• Mapelson A Fresh gas flow and exhaust exactly opposite of Mapelson D Very effective for spontaneously ventilating patients Requires about 200-300 mL/Kg/m fresh gas flow for controlled ventilation, 70-100 mL/Kg/m for **spontaneous** ventilation • Mapelson D Used in pediatric cases because of very low resistance Requires about 200-300 mL/Kg/m fresh gas flow for spontaneous ventilation, 70-100 mL/Kg/m for **controlled** ventilation Bain modification places fresh gas tubing within the expiratory hose Know Controlled vs spontaneous Mapleson D is also know a coaxial circuit
36
Exporsure to N20 can cause what negative effects? NIOSH recommendations?
• Chronic low-level exposure to N 2 O: Spontaneous abortion Fetal malformation Cancer Neuropathy Behavioral changes • NIOSH recommendations: N 2 O \< 25 ppm Halogenated agents \< 2 ppm Halogenated agent + N 2 O \< 0.5 ppm
37
Requirments of OR ventilation systems
• Air turnover is the single most important factor in reducing anesthetic air pollution • 10 exchanges per hour or more is required • Fresh air enters the OR through ceiling vents and leaves through floor vents
38
Rules for the Scavenging System? Required size of hose, Disposal routes?
• Required by JCAHO • Reduce anesthetic loss to OR by 90% • 19 mm hose, rigid enough to hold 10kg/cm • Scavenger interface Closed reservoir Open reservoir • Disposal Routes Active – to specialized wall suction at \> 30L/min Passive – to floor vents
39
Closed vs. Open Scavenger??
40
What are the delivered #'s for a jet ventilator?
Jet Ventilator Narrow catheter placed in trachea Oxygen at **25 – 30 psi** delivered for **1 – 1.5 secs x 12/min** Tidal volumes of **400 – 700 mL** obtained -Jet ventilator works on the **venturi/bernoulli** principle • High-frequency ventilator Gas transport by diffusion rather than convection
41
Volume Ventilators Componets? Vent Cycle? What is if effected by?
Commonly used on anesthesia machines • 2 components Bellows assembly Control box (Hanging bellows ventilators don’t meet standard of care) • Ventilatory cycle Closure of relief valve (to scavenger) Pressurization of bellows chamber Discontinuation of pressurization to begin exhalation Refilling of bellows from exhaled volume and fresh gas Flow Opening of relief valve to vent excess gases to scavenger • Unaffected by changes in compliance, but affected by leak
42
Fresh Gas Flow Coupling
• During inspiratory phase, fresh gas flow adds to the tidal volume • **High FGF may significantly increase TV and minute ventilation** • Usually not seen with newer piston-driven ventilators, which can deliver very accurate TVs to patients with poor compliance or very small patients
43
High-frequency Ventilators rate indicated for??
* Small tidal volumes – at or less than dead space * Rapid rates – **60** or more breaths/minute * CO2 retention corrected by decreasing rate * Indicated for bronchopleural fistula, to improve oxygenation during one-lung anesthesia, tracheal reconstruction and extreme loss of lung compliance
44
Capnography uses what law? What are the two types? How are the measured??
• Two types available Side stream – gas sample brought to machine analyzer Main stream – analyzer positioned in gas flow • Measurement techniques Infrared – infrared light is strongly absorbed by CO 2 – Beer-Lambert Law Mass spectrometry-- not commonly done Chemical indicators
45
Capnogram Ohases, What does each one mean?
I. The inspiratory baseline Fresh gas rushes past the sampling site CO 2 concentration approaches zero Dead space gas at end of Phase 1 II. Expiratory upstroke (transition phase) Exiting alveolar gas contains CO 2 and causes rapid upstroke Airway obstruction may produce a decrease in slope Decrease in the alpha angle seen III. Expiratory plateau Capnogram plateaus as a stable amount of CO 2 is exhaled May have a slight incline as lung units with lower V/Q ratios empty IV. Inspiratory downstroke Fresh gas drawn past sampling site Downstroke may be slowed by an incompetent inspiratory valve
46
Increased Airway resistance
47
What causes it\>
Rebreathing Elevated baseline – phase 1 Caused by failed expiratory valve, exhausted CO 2 absorber Can be caused by inadequate fresh gas flow in Mapelson circuits
48
what causes cardiac oscillations?
Cardiac Oscillations Changes in intracardiac volume resulting in gas movement Rhythm corresponds to pulse
49
Spontaneous ventialtion on capnography can be known as?
Spontaneous ventilation Sometimes called “Curare Clefts”
50
PaCO2 – PeCO2 Differences
• Normally 3 – 5 mmHg • **Changes in V/Q ratio** Shunt has very little impact on end-tidal CO 2 Changes in dead space have a large impact on end-tidal CO 2 • Sample size Very small children will have small exhaled volumes. Dilution from fresh gas flow may reduce apparent end-tidal CO 2 • Machine errors
51
Oxhyemoglobin dissociation curve, P50 PaO2, = what sat Formula for Functional Saturation
P50= 27mmHg PaO2, 40, 50, 60, = Sat of 70, 80, 90
52
Pulse Oximeters What Law? Hos is O2 sat determined?
• Makes use of light absorbance – Beer-Lambert Law • Tissue contains many absorbers of light Blood pulsations used to determine arterial absorbance • Absorbance of 2 wavelengths of light to determine oxyhemoglobin and reduced hemoglobin • Ratio formed and saturation determined
53
What is the accuracy of O2 Sat What cae cause large decreases in pulse Ox What can does Carboxyhemoglobin do? What about another one?
• Accuracy 2% x 1 standard deviation Accuracy within 2%, 68% of the time • Dyes can cause large decrease in measured saturation • Carboxyhemoglobin causes false elevation in measured saturation • Methemoglobin results in sat of 85%
54
Cerebral Oximetery What technology? What does is show? What is a negative sign, how long?
• Cerebral oximeters obtain continuous, noninvasive cerebral oxygenation values using near-infrared spectroscopy (NIRS) technology (650 - 900 nm) • Saturations are determined by measuring the light absorbed vs. light transmitted. • Saturation levels reflect capillary oxygen saturation levels • Saturations are lower than seen with pulse oximetry and trend analysis much more diagnostic • Reduction \> 20% for more than 4 minutes indicate potential for neurologic deficits
55
What are 3 Oxygen Analyzers? And how do they work?
Galvanic- Volts Polarographic Sensors- amps Paramagnetic analyzers- require no calibration, institaneous
56
# test prompt Principles of Electricity Name a common Law? What is the formula? DC vs. AC?
• Ohm’s Law E = IR (E = voltage, I = amperage, R = resistance) • Power E x I = power (measured in watts) • DC vs. AC Electron flow only in one direction = DC Electron flow reverses at regular intervals = AC
57
AC Electricity? What is the resistive fore in AC circuit? Explain it further
• Impedance  resistive force in AC circuit • Impedance (Z) Z = frequency x inductance Z = 1/(frequency x capacitance) • Changes in frequency result in changes in impedance • Inductance  electrical current can be induced in a separate wire or iron core
58
Explain Grounded Electrical Power?
• As supplied by electric utility, power is grounded • In a grounded system current will flow between the “hot” wire and any conductor (patient) with ground • If patient is touching ground only contact with the “hot” wire is needed for shock to occur
59
Electrical Shock Hazards, Explain? Macroshock? BOARD Question?
• AC has greater propensity to cause V-fib • Tissue damage occurs: Disruption of normal cellular electrical activity Thermal injury – may be internal along path of conductivity • **Macroshock (at 60Hz)** _1mA = threshold of perception 10-20 mA = “let go” current 50 mA = pain_ **-DRAG and DROP Question**
60
Ungrounded Power What ungrounds the Power? What monitors the power? -Alarm numbers?
• In the OR power is ungrounded • Isolation transformer is the device that “ungrounds” the power • Line isolation monitor monitors the integrity of the isolated power system Alarm is usually set to 2-5 mA
61
What distance does a bovie need to be from a pacemaker?
15cm,
62
Microshock
* A catheter or wire in the heart can deliver high current density * As little as 20 microamps may induce V-fib * Isolation transformer does not prevent microshock * Isolation monitor will not detect risk of microshock
63
Explain the diffrent kinds of lasers?
• Laser reactivity depends on wavelength: Argon – absorbed by hemoglobin and melanin • CO2 laser blocked by any type of clear- (Cornea) glass or plastic, absorbed by water, limited tissue penetration • Nd:YAG and Argon lasers require special protective eyewear, transmitted through clear materials, deep penetration, (retinal damge) • Airway fires a risk from ETT ignition
64
Airway Fire Management?
• Primary Response Discontinue O 2 source Remove endotracheal tube Mask ventilate with lowest possible FiO 2 • Secondary Response _Recommendations vary from author to author_ Re-intubation Short term steroid administration Antibiotic administration Bronchoscopy Ventilatory support
65
Temperature Monitoring? Hypothermia? shivering? What does a MAC of gas do?
**Temperature Monitoring** • Hypothermia – body temperature less than 36 o C • Postoperative shivering increases oxygen consumption by a factor of 5 • Radiation accounts for 40% of heat loss. Convection and evaporation account for about 30% • Conduction accounts for 30% of heat loss • One MAC decreases vasoconstriction and shivering threshold by 2 – 4 o C. ## Footnote **Radation\>Convection\>Evaporation\>conduction**
66
Temperature 3 phases of intraoperative hypothermia? Core temp? -most accurate? least accurate?
• Three phases of intraoperative hypothermia: 1) **Redistribution** of heat from core to periphery. Occurs in 1 st hour and results in a 1 – 2 o fall 2) **Steady decline** occurs in following 2 – 3 hours 3) **Equilibration** – losses equal metabolism • Accurate core temperatures can be obtained from: PA, distal esophagus, tympanic membrane, nasopharynx • Mouth, rectum, bladder, axilla are reasonable
67
Warming Methods?
Warming Methods • Treatment of hypothermia is ideally focused on intraoperative prevention • Active rewarming – application of an external heat source: 1. -Heated blankets – conductive heat source 2. -Radiant warmers – radiant heat source 3. -Forced air warmers – convective heat source. Forced air warmers have been shown to be the most effective • Burn injuries have been associated with all types of active rewarming devices *– Use of external heat sources are contraindicated in pts with severe PVD or during hypoperfused states (i.e. aortic cross-clamping)*
68
Cell Saver? What does it do to blood? What is the the HCT of Cell saver blood
Blood Salvage (Cell Saver) • Device anticoagulates blood as it leaves the surgical field • Cells are washed in NS and centrifuged to a HCT of 45 – 65% • Contraindications – presence of infection, malignant cells, urine, bowel contents and amniotic fluid • Washing process removes platelets and coagulation factors, but not bacteria • Leukocyte filters often used to trap bacteria
69
BIS Ranges?
• BIS ranges – 100 - 90 = awake, unanesthetized patient – 90 – 70 = light to moderate sedation – 70 – 60 = deep sedation (probable amnesia) – 60 – 40 = general anesthetic state – 40 – 10 = deep anesthetic state & burst suppression – 10 – 0 = flat-line EEG pattern • Causes of unexpected BIS results/changes – Change in level of surgical stimulation – Change in level of anesthesia or sedation – Change in body temperature – Change in level of neuromuscular blockade & shivering (falsely ↑ s EMG) – Presence of high-frequency electrical device e.g. Bovie, pacemaker – Placement of temporal lead over temporal artery – Use of pressors, ketamine \*\*BIS lags behind real-time by approximately 10-15 seconds
70
Where is DISS located? What is the DISS
Back of the machine, ball and spring, you supply the endergy. It is for the Gaslines to be plugged into the wall, only DISS for the wall. VS. the Pin Index- designed for the Tank to be hooked up to the machine.
71
High Intermdiate Low Pressure systems?
hanger yoke yoke block with check valves (free floating) cylinder pressure gauge cylinder pressure regulators ventilator power inlet pipeline inlets, check valves, pressure gauges flow meter valves oxygen pressure-failure devices oxygen second stage regulator flush valve flow meter tube vaporizers check valves common gas outlet
72
What are the 3 primary valves on the gas machine?
Free Floating- Examle DISS- prevents gas from leaking Ball and Spring- You supply the energy (all or none) Diaphragm- Diaphram (1st and 2nd stage regulators)
73
Factors that may cause a failure to deliver adequate oxygen to alveoli from the anesthsia machine or patient?
––empty oxygen cylinder ––incorrect cylinder on oxygen yoke ––closed oxygen cylinder valve ––oxygen flow meter off ––oxygen leak within the machine or flow meter ––incomplete or absent circuit unidirectional valves ––breathing circuit leak ––inadequate ventilation
74
your and O2 Molecule going through the machine, what is the path?
Oxygen E cylinder → open cylinder valve → hanger yoke system → opens free floating valve of this E cylinder AND simultaneously closes the free-floating valve of the other hanger yoke system AND activates the Bourdon Gauge to read cylinder pressure. Now back to the open free-floating valve → first stage regulator (diaphragm valve) reducing cylinder pressure to intermediate pressure, which is 45psig, and now simultaneously to the following: → oxygen pressure sensor valve → flush valve → DISS ( closes free floating valve and PREVENTS CYLINDER OXYGEN FROM ESCAPING THE GAS MACHINE !!!!!! → second stage regulator (converts intermediate pressure to low pressure or 16 psig) → to gas flow manifold (flow meters) → vaporizer → common gas outlet → down through the soda lime canister → inspiratory valve → inspiratory limb of the breathing circuit → endotracheal tube/patients lips.
75
What are all the intitites that regulate cylinder gas?
„„Department of Transportation (DOT)—established requirements for the design, construction, testing, marking, labeling, filling, storage, handling, maintenance, and transportation of compressed gas cylinders „„National Fire Prevention Association (NFPA)—same as for CGA: contains recommendations for the location, construction, and installation of bulk oxygen systems (NFPA 50) „„American National Standards Institute (ANSI)—sets basic performance and safety requirements for components of anesthesia machines, endotracheal tubes and connections, pressure and vacuum, and gas pressure regulators. „„National Institute of Occupational Safety and Health (NIOSH) and Occupational Safety and Health Act of 1970 (OSHA)—standards to protect the health and safety of workers. „„Food and Drug Administration (FDA)—promulgates standards for medical devices and gases. American Society for Testing Materials (ASTM)—assesses technology and revises standards. „„Joint Commission on Accreditation of Hospitals (The JC)—voluntary accrediting agency.
76
What if the vaporizer is tipped?
Will carry more gas than anticipated, need to send back to company for recalibration.
77
Hanger Yoke Explain,
Hanger yoke is actually the valved, immideatly after the O2 tank, A dual hanger yoke allows gas to be taken from the tank with the most pressure.
78
What is Avagadros number? what is the law?
Avagadros # is 6.02 X10 \>23, Avagodras law is, any gas with one mole of occupies a volume of 22.4 liters at 1 atm and 0 degrees C.
79
van der Waal’s Relationship
Deviation from the ideal state (PV = nRT) is described mathematically by the van der Waal’s equation. Real gases deviate from this ideal state. van der Waal’s equation corrects for deviations from ideal. van der Waal’s relationship (expressed below) assumes that gas molecules have finite volume a and that gas molecules attract one another b.
80
**Explain Ficks law of diffustion.** 4 effects used? What are the factors that effect Ficks Law
**Application for Ficks Law of diffustion** (1) the concentration effect, (2) the second gas effect, (3) diffusion hypoxia, and (4) why turning on the N2O leads to an increase in volume (or increase in pressure) in gas spaces in the patient’s body. According to Fick’s law of diffusion, the rate of diffusion of a gas into or out of the blood is proportional to its blood solubility. Fick’s First Law – For a given solute, the major determinant of the rate of diffusion is the concentration gradient **Factors that effect Ficks Law** 1. The partial pressure difference of the gas across the membrane. 2. The area of the membrane 3. the solubility of the gas in the membrate 1. The tickness of the membrane 2. the square root of the molecular weight of gas. Gases that are more soluabe will diffuse in greater quantites into the blood - ( This is Ficks law) Ficks law explaines the diffusion of gases between a gas phase and a liquid phase.
81
N20 Is how many times more soluable than N2?
X34
82
What 2 laws apply to the diffusion of nitrous?
Ficks law, and Grahms law.
83
Explain Boyles law? Examples?
You sitting and breating Applying pressure to a bag 500 ml at 2 ATM is 1000ml at 1 TM Plethysmography - (measures changes in volume) Bellows Ventilator An O2 tank will releaase 660 liters into the atmosphere
84
Explain Charles Law Give examples
ET tube in autoclave
85
What equation involves, Boyles, charles and Gay lussac
The ideal gas law PV=nRT n=number of moles R- universal gas constant
86
Dalton's law?
1. Permits calculation of the % concentration of a gas by dividing the partial pressure of the gas by the total pressure. 2. Permits calculation of the partial pressure of a gas by multiplying % concentration by total pressure. N2O is 80% of the atmosphere= so its partial pressure 9s 600 0.8 X 760=600 If you are in the mountains it is lower pressure. so the O2 will still be the same % but will be a lower pressure. 2L/4L O2/N20 at 710mmgh = 236mm vs 474 mm *Do not confuse with Henry's Law= amount of gas that dissolves in a liquid is proportional to the partial pressure of the gas in the gas phase.*
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Henry's law
Henry's Law= amount of gas that dissolves in a liquid is proportional to the partial pressure of the gas in the gas phase. * the amount of O2 dissolved in blood 0.003 * the amount of CO2 dissolved in Blood 0.067
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What is heat of vaporization? What is Latent heat of vaporization?
It takes energy to break from the liquid state, A liquids **heat of vaporization** is the *number of calories necessary to convert 1ml liquid into a vapor.* **Latent heat of vaporzation** is more precisely defined as the number of calries required to change 1 G of liquid into vapor without a temperature change.
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Define relative humidity?
the ratio of the amount of water vapor present in the air, to the maximum amount of vapor the air can hold at the same temp. -The more heat in the air- the more vapor it can hold
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Joule-Thompson effect
adiabatic cooling of the gas in the cylinder, compressed gas release (Compressed Air Tank) Joule is COOL! cryoprobe uses the Joule-Thompson effect
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Critical temp Critcal pressure?
temp above which a gas cannot be liquidfied no matter how mouch pressure is applied. O2- -119 Centigrade Critical pressure- minimum pressure necessary to liquify a gas at its critcal temp.
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What is the boling point?
the point at which a liquids vapor pressure equals that of the total atmosphere pressure. Des will boil in the moutains, because its vapor pressure will be greater than the barometric pressure
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Ohms law? How does it apply to flow
Math whise , flow through a tube is inversaly proportional to resitance, Omhs law allows calculation of SVR, CO, MAP and CVP
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Poiseulle's law?
flow is directly proportional to 1. the pressure drop along the tube 2. the forth power of the radius inversly 1. the length of the tube 2. vicosity of the fluid If the radius is doubled- the flow increases by 16X If the radius is tripled- the flow increases by 81X It is 81 because it is 1/34
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Viscosity and laminar flow?
flow is inversley proportional to viscosity
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What is Reynolds number?
2000 Flow becomes turbulent when viscosity reaches critical level. Conditions that change Laminar to turbulent 1. changing directions 2. increased velocity 3. rough walled The greater the density, the less the flow When flow is high and turbulent- **Density** determines flow. When Flow is slow and laminoar- **Viscosity** determines the flow. Turbulent (orifice flow) can occurr when the length is greater than the diameter.
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Venturi? How does it operate?
It operates on the Bernoulli principle, the lateral pressure exerted by a fluid going through a tube of varying diameter is lowest at the narrowest part, where the velocity is greatest. Used in 1. nebulizers 2. atomizers 3. high frequency jet ventilotors 4. Venturi mask
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Law of Laplace
tension in the wall of a hollow structure is proportional to the radius. Cylinders: T = Pr Spheres: T = Pr/2 **Surfactant** is a chemical in alveoli that lowers surface tension. It is more concentrated in smaller alveoli and lowers the surface tension more in smaller alveoli than larger alveoli. In ARDS- The alvoli act like soap bubbles, small empting into big due to greater pressure inside the soap bubble.
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Macro vs. Microshock
Macro= voltage applied to skin or tissue, 1-25 amps can cause V-fib Micro= small volts directly to the heart, 50 microamps required to cause V-fib
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What 3 things are grounded in the Operating room?
1. power supply 2. the patient 3. the floor
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What triggers the alarm of the line isolation monitor?
if isolate powerline is less than 60,000 ohms or ir fault would draw more than 2mA, If the alarm goes off- It could be to much equipment plugged in, could be 1 piece of faulty equipment, identify by unplugging each piece one at a time, if not for life support measures it should be removed from the room.
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What are the agencies that regulate gases?
USP/NF- writes regulations for purity of gas FDA- enforces teh purity standrsds, inspect DOT- filling and manufacturing of gas cylinders cylinder inspected every 5 years,
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how often should a cylinder be inspected?
every 5 years unles special permit, up to 10 years.
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common contaniments of medical gas lines?
oil, **water(most common)**, bacteria, particulate matter, and residual sterilizing solution.
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what is a fusible plug?
It is a soft wood metal, tht will be come soft at high temperature and let the cas discharge from the cylinder. It does not help with overfilling, only elevated temp.
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Why would you "crack" a valve on a E cylinder?
to remove dust and debrie from the valve, to help prevent fire or explosion when the valve is opened later.
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explain having 2 flowmeter tubes?
2 Tubes means you just have one taper, 1 tube means you need to dual taper in one tube, so that you can accuartely dial low flow/ high flow
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how are flow meters calibarted for gases? Based on what property? What is diffrent about the knob for O2
Low flow is the viscosity, High flow is the density, O2 knob is 1. fluted 2. projects beyod control knobs 3. larger in diameter than other control knobs
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5 features of anetheisa workstation vaporizers? Whar are 3 characteristics for varible bypass? What is an anesthesia work station?
1. concentration-calibrated 2. interlock 3. must indicate the liquid level in order to prevent overfilling 4. keyed-filler devices 5. must not dicarge anestheic from vaporizer even at maximum fresh gas flows 1. agent specific 2. temp compendated 3. flow over (variable bypass) Vaporizer shoul be located between flow meter and common gas outlet (this is out side the circle system) The work station is defined by ASTM, 1. gas supply 2. ventilator 3. monitoris 4. protection devices
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What is unique about the TEC6?
It is not varible bypass, it is ectromechanically coupled dual circuit, gas vapor blender, Des has to be heated to 39C, which delives a pressurized vapor of 1300 or 1500 Fresh gas flow never comes in contact with Des liquid, The Tech6 does not compensate for changes in elevation- The *concentration* is unaffected, but the partial pressure delivered is less, therefore you will need to increase concentration to deliver equivaent **partial pressure**. If you are asked to calculate partial pressure of des at 5% all you do is .05 X 760 =
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Pumping effect was on older vaporizers, What did it cause
Back pressure during low flow would cause and increase concentration to be delivered. Newer vaporizers decrease the size of the vaporizing chamber, vapor saturated gas cannot make its way back into the bypass channel, so the pumping effect is prevented.
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What are 6 hazards of moder vaporizers?
1. incorrect agent 2. tipping 3. overfilling 4. electronic falure 5. reliance on breath by breath gas analysis,
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What is the main function the the check valve,
they prevent retrograde flow, and minimize downstream pressure, during postive pressure ventilation,
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8 required monitors on the anesthesia work station?
1. exhaled volume 2. inspired O2 3. oxygen supply failure alarm 4. hypoxic guard system 5. anesthetic vapor concentration 6. pulse oximetery 7. blood pressure 8. ECG
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How long can I high priority alrm be silenced?
maximum of 2 minutes.
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5 componets of the scavenging system?
1. gas collecting system 2. transfer tubing 3. scavenging interface 4. gas disposal tubing 5. active or passive gas disposal
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5 conditions that can fool a proportion limiting systems
1. wrong supply gas 2. defective pneumatics or mechanics 3. leaks downstream, 4. inert gas 5. dilution of inspired oxygen The link system for the N20 is the link-25 proportioning system, it allows a 3:1.
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What is a double-circuit ventilator?
separates breathing system gas from driving gas.
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What are 7 criteria for taking a patient off a vent?
1. VC 2. PaO2 \>60 3. maximal negative inspitory pressure \>20 4. normal pH 5. RR rate \<20 6.
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What TV and Resp rate for patients?=
10-15ml/kg slow breathing 6-8
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signs of exhausted CO2?
1. increased ETCO2, 2. respiratory acidosis, 3. hypervntilation, 4. sympathetic activation 5. increased bleeding 6. color indcatior late signs 1. increased HR and BP 2. dysrhythmias
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How many CO2 liters can be absorbed from 100gm of sodalime?
15liters
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What are the end componets of sodalime/amsorb after it interacts with CO2
1. Calcium carbonate 2. sodium hydroxide 3. potassium hydroxide 4. heat 5. water Amsorb 1. Ca (Oh)2 2. Ca CL2 3. CaSO4 4. polyvinylpyrrolidone, 5. water Calcium hydroxide is the most abundant component of both soda lime and amsorb The reaction that takes place is known as Neutralization.
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Mapelson efficency with respect to prevetion of rebreathing during **spontaneous/controlled** ventilation?
**Spontaneous**- A\>DFE\>CB **_Controlled_**- DFE\>BC\>A The most commonly used system for delivery of anesthetic gass and O2 to children and adults. = Semi- closed
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Where should the O2 senseor be placed?
on the inspiratory limb
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Which part of the anesthesia machine is most vulnerable?
THe lower pressure circuit b/c it is subject to breakage and leaks.
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7 required componets of the anethesia machine
1. battery 30min 2. almars 3. monitors 4. breathing circuit pressure limited to 125cm 5. nondetachale electrical supply cord 6. cylinder supplies 7. flowmeters
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Why does looking at volume returned on ascending bellow not reflect ture tidal volume?
due to compression of gasses, epansion of the breathing circuitry, gas that enters the bellows during expiration, consistis of the patient gas as well as fresh anestheitc gases.
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lighted sylet shape you shoud mak?
lighted sylet oral J shape, 75-120 (60-80 peds)degrees. Nasal- should take shape of the paient.
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explain sterlization vs disinfection.
sterilzation includes baterial spores Autoclave just uses steam. 1. 121C=15min 2. a few seconds 150C
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What are some of the disinectants?
* amonium componds * alcohols * glutaralehydes * hydrogen peroxide * formaldehyde * chrine Ethylene oxide- for temperature sensitive equipment. hydrogen perxoide and glutaraldehyde will destory spores.
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EEG Wave categorizes
1. alphat, 8-12Hz 2. beta, \>12 3. delta, -0-4Hz 4. theta. -4-7 Hz Anesthesia is theta waves - delta- sleeping beta- thinking, awak When anesthesia is incresed, you get increased amplitude, followed by isoelectric EEG at a MAC of 1.5-2
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What is the value of somatosensory evoked potential monitoring?
somatosensory evoked potentials- integrity of posterior/**dorsal** spina cord, of the **dorsal-lemniscal** system. neuromuscular blockade will not alter transmission of action potentials in the sensory tracts. Halotane effects it the least, Enflurane the most, Nitrous also effects it. Things that effect SEPs 1. temp- (effects the most) 2. hyotension 3. hypoxia 4. hypocarbia 5. isovolemic hemodilution (the least) SEPs monitor flow through the posterior spinal arteries. autitor SEPS- VIII- Most resistant to SEPs Optic monitoring appropriate for pituitary and transsphenoidal surgery Optic SEPS= most sensative, Aesthesia with minimual effect- prop. barbs, fent, _ketamine, etomidate, opieates - dont effect SEPs_ hyothermia can effect as well. **MEPs**-the wake up test measures the anterior spinal cord BIS is not effected by hypnotic agents, opioids or analgesics. The BIS is slightly increased with Ketamine.
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What is cerebral oximetry?
measures regional blood hemoglobin stauration with near-infrared optical spectroscopy. NRIS measures all hemoglobin, pulsatile and nonpulsatile in a mixed microvascular bed. It measures objectively for hyoperfusion. It has the advantage of being used during non-pulsatile flow like that of Circulation arrest.
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O2 canula saturation,
1. 21 2. 25 3. 29 4. 33 5. 37 1-5 liters per min
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**How do you calcuate FiO2?**
You need to work on this one and now it!!!
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What is the chemical reaction in soda lime, Beable to write it all out.
Reactions of CO2 in Soda Lime 1. CO2 + H2O → H2CO3 2. H2CO3 + 2NaOH (2KOH) → Na2CO3 (K2CO3) + 2H2O + heat 3. Na2CO3 (K2CO3) + Ca(OH)2 → CaCO3 + NaOH (2KOH)
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HME. Explain the 2 diffrent types
***Hydrophobic*** HMEs have a hydrophobic membrane with small pores that is pleated to provide a greater surface area. High ambient temperature may decrease the effectiveness of hydrophobic HMEs. The airway resistance of hydrophobic HMEs increases only slightly if wet. ***Hygroscopic*** HMEs contain a wool, foam, or paperlike material that is coated with a chemical that helps it to retain moisture. Hydrophobic HMEs are effective at preventing the transmission of the *hepatitis C virus* than hygroscopic HMEs. if hygroscopic HMEs become wet, they may lose their ability to filter airborne pathogens and airway resistance may *increase substantially*. Are considered _more effective_ at preserving heat and humidity than hydrophobic HMEs.
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How do you perform post-tetanic tetany?
50-Hz for 5 sec tetanic stimulation is applied, followed by a 3 second pause, then 1-Hz single twitch stimulations are applied in a series. The number of stimulations that produce a visible muscle twitch is the post-tetanic count.
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Will fresh gas flow contribute to tidal volume?
when the ventilator is being used a portion of the fresh gas flow will contribute to the tidal volume. This effect increases if the fresh gas **flow rates** are high, if the **I:E ratio** is high, and if the patient has a **slower respiratory rate.**
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