Equations to know Flashcards
Flow
Flow ∝ ∆P/R → as pressure difference increases flow increases, as resistance increases flow decreases
Flow rate
Flow rate = volume of blood that passes a given point per unit time (L/min, how much)
Velocity of flow
How is capillary velocity slow?
v (velocity) = Q/A (Q = flow rate, A cross sectional area of a tube)
Velocity of flow = distance a fixed volume of blood travels in a given period of time (how fast)
Capillaries have the greatest resistance (smallest r) which should increase velocity but because total cross-sectional area of capillaries is large, reduces velocity of blood flow so that material exchange can occur
Cardiac output equation
CO = stroke volume x heart rate
Frank-Starling law of the heart:
stroke volume ∝ EDV (larger venous return → stronger contraction to eject more blood)
Poiseuille’s law:
R = 8L(η/r4) or R ∝ Lη/r4
Resistance is proportional to length and viscosity and inversely to radius^4
Pulse pressure and mean arterial pressure equations
Pulse pressure = systolic - diastolic
Mean arterial pressure = (systolic + diastolic + pulse pressure)/3
Transcytosis:
Transport of large solute from one side of capillary in vesicle to other in continuous capillaries
Permanent pore formation in fenestrated capillaries
Dalton’s law:
total pressures = sums of all partial pressures
Boyle’s law
P1V1=P2V2
pressure exerted by a gas or mixture of gases in a sealed container is created by the collisions of moving gas molecules with the walls of the container and with each other.
Chemical reaction for the conversion of CO2 to HCO3- and enzyme
CO2 + H2O -> HCO3- + H+ by carbonic anhydrase (CA)