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Renal I > Equations and Nephron Stuff > Flashcards

Equations and Nephron Stuff Flashcards

1
Q

Clearance

A

Cx = Ux*V/Px

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2
Q

Filtration Fraction

A

FF = GFR/RBF

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3
Q

Reabsorption

A

R = Filtered Load - Excretion

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4
Q

Filtered Load

A

FL = GFR * Px

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5
Q

Ultrafiltration Coefficient

A

Kf = Lp * Sf (Permeability * SA)

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6
Q

Glomerular Filtration Rate

A

GFR = Kf * PUF

starling forces, capillary ultrafiltration pressure

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7
Q

Osmotic Equilibrium

A

OEq = (mOsmECF + mOsmICF)/(VECF + VICF)

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8
Q

Post Osmotic Equilibrium Volume

A

ICF = mOsmICF/Serum mOsm

ECF = (mOsmECF + mOsmSolution)/Serum mOsm

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9
Q

Aldosterone Action and Location

A

Increases Na+ reabsorption at the collecting duct principal cells

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10
Q

ADH Action and Location

A

Increases H2O reabsorption via Aquaporin 2 at the collecting ducts

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11
Q

Proximal Convoluted Tubule Reabsorption Numbers

A

100% of Glucose and Amino Acids
70% of Na, K, P, Ca, H20
50% of Urea

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12
Q

Na/KATPase Locations

A

PCT
Ascending Limbs of LOH
Collecting Ducts

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13
Q

Aquaporin Locations

A

AQP-1 is in PCT

AQP-2 is in collecting ducts

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14
Q

Glucose Transporters

Location and % of work

A

SGLT-1 is in distal PCT (10% of reabsorption)

SGLT-2 is in proximal PCT (90% of reabsorption)

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15
Q

Na-K-2Cl Cotransporter Location

A

Thick ascending limb of LOH

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16
Q

Na-H3 Exchanger Location

A

In PCT

17
Q

NaCl Cotransporter Location

A

In ascending limb of LOH and DCT

18
Q

NaHCO3 Cotransporter Location

A

In PCT

19
Q

Excretion

A

E = Ux * V

20
Q

Thiazide Diuretics Action and Location

A

Decrease NaCl reabsorption in the DCT

Increases Ca reabsorption in DCT

21
Q

Loop Diuretics Action and Location

A

Inhibits Na-K-2Cl transporter in thick ascending loop of henle

22
Q

Spironolactone Action and Location

A

Inhibits Na-K exchange in DCT and Collecting Duct to retain K and lose Na/H2O

Renal I (2 decks)

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