Equations Flashcards
Anion gap
Na - (Cl + HCO3) <= 12
MUDPILES
Methanol, Uremia, DKA/AKA, Paraldehyde/phenformin, Iron/INH, Lactic acidosis, Ethylene glycol, Salicylates
Osmolar gap
2Na + BUN/2.8 +glucose/18 + ETOH/4.6 = 285-295
>10: toxic alcohols, mannitol, lorazepam drip
Total body water (L)
Wt (kg) x 0.6
Parkland formula
4 mL x Wt (kg) x %BSA
1st 1/2 in 8 hours
2nd 1/2 in 16 hours
MAP
1/3 SBP + 2/3 DBP or DBP + (SBP - DBP)/3
Pediatric ETT size
Age/4 + 4 (uncuffed) and age/4 + 3 (cuffed) (or minus 0.5)
2 x ETT = NG/OT/foley
3 x ETT + depth of ETT
4 x ETT = chest tube
Neonate: premature 2.5 uncuffed, full-term 3.0 uncuffed
A-a gradient
140 - (PaO2 + PaCO2)
normal = (age +10)/4
Corrected Na in hyperglycemia
Na + 2.4 (glucose-100)/100
Or use 1.6
Winters formula (expected pCO2)
1.5 x HCO3 + 8 (+/- 2)
To assess respiratory compensation in metabolic acidosis
“Rule of 15” - if there’s a metabolic acidosis
HCO3 + 15 (+/-2) = pCO2 + last 2 digits of pH (non mixed)
GCS
Eye (spontaneous 4, verbal 3, pain 2, none 1)
Voice (oriented 5, confused 4, inappropriate 3, moaning 2, none 1)
Movement (obeys 6, localize pain 5, withdraws 4, flex 3, extend 2, none 1)
Fluid maintenance
“4 - 2 - 1”
0-10 kg: + 4 ml/kg/hr
10-20 kg: + 2 ml/kg/hr
>20 kg: 1 ml/kg/hr
Ranson criteria
On admission - GLOWS
Glucose >200, LDH >350, older age >55, WBC >16k, AST (SGOT) >250
At 48 hours - BOB CHF
Base deficit (24 - HCO3) > 4, O2 < 60, BUN increase >5, Ca < 8, Hct drop > 10%, fluid deficit > 6L
Jones criteria
2 major or 1 major + 2 minor
Major: polyarthritis, carditis, subcutaneous nodules (wrist/elbow/knees), erythema marginatum, syndeham chorea
Minor: fever, arthralgia, h/o RF, prolonged PR, elevated CRP/ESR, GBS infection
Diabetes diagnosis
Fasting blood glucose > 126
Random blood glucose > 200 + symptoms
Blood glucose > 200 after glucose tolerance test
Hgb A1c > 6.5%
DKA diagnosis
Serum glucose > 250 pH < 7.3 Serum bicarb < 12 AG > 10 \+ serum/urine ketones
Water deficit
0.6 x wt (kg) x [Na/140 - 1]
50% in first 12 hours, rest over next 24 hours
Hypernatremia goal, decrease 1-2 meq/hour
Hypercalemia symptoms
Bones, stones, moans, thrones, and psychic overtones
Bone pain, urinary/biliary stones, abdominal pain, N/V, polyuria (porcelain throne), depression, anxiety, insomnia
Shortened QT
< 12 no treatment, 12-14 symptoms based, >14 treat
Lithium causes hypercalcemia