Equations Flashcards
1
Q
How do you calculate rate of elimination?
A
Rate=Cl x Cp
2
Q
How do you calculate volume of distribution?
A
Vd=dose/initial conc of drug in plasma
3
Q
What is the relationship between Vd and half life?
A
t1/2 = (0.693xVd)/Cl
4
Q
How do you find the time course of drug elimination from the body?
A
Ct = Co x (0.5)^n
5
Q
How do you calculate the time course of drug accumulation within the body?
A
Ct = Co x (1-0.5)^n
6
Q
How is the rate of excretion via filtration calculated?
A
Cl(fil) = GFR x fraction of unbound drug
