Equations Flashcards

1
Q

C =

A

total conc.

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2
Q

Cp0 =

A

conc @ time zero

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3
Q

Css =

A

steady state conc.

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4
Q

ke =

A

elim rate constant

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5
Q

ka =

A

absorb rate constant

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6
Q

t =

A

time between bolus
and level

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7
Q

Cl =

A

clearance

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8
Q

Vd =

A

volume of distribution

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9
Q

D =

A

dose

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10
Q

F =

A

bioavailability

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11
Q

Half-life

A

t1/2 = 0.693/k

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12
Q

Elimination rate constant

A

ke= 0.693/t1/2

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13
Q

Clearance

A

Cl = ke x Vd

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14
Q

Volume of distribution

A

Vd = F x D / Cp

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15
Q

Loading
Dose

A

D = Vd x Css

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16
Q

Steady state concentration
(IV)

A

Css = ka / (Vd x ke)

17
Q

Steady state concentration (PO)

A

Css = (1.44 x D x F x t1/2) / (T x Vd)