Equation Review Flashcards

1
Q

Sensitivity

A

Sensitivity = TP / (TP + FN)

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2
Q

Specificity

A

Specificity = TN / (TN + FP)

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3
Q

Positive predictive value

A

PPV = TP / (TP + FP)

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4
Q

Negative predictive value

A

NPV = TN / (TN + FN)

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5
Q

Relative risk

A

[a/(a+b)]/[c/(c+d)]

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6
Q

Attributable risk

A

[a/(a+b)]-[c/(c+d)]

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7
Q

Number needed to treat

A

1/absolute risk reduction (ARR)

1/[Event Rate (control) - Event Rate (treatment)]

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8
Q

Number needed to harm

A

1/attributable risk increase (ARI)

1/[Event Rate (treatment) - Event Rate (placebo)]

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9
Q

Hardy-Weinberg equilibrium

A

p^2 + 2pq + q^2 = 1

p + q = 1

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10
Q

Henderson-Hasselbalch equation

A

pH = pKa + log ([HCO3-]/ 0.03 PCO2)

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11
Q

Volume of distribution

A

Vd= (amount of drug in the body) / (plasma drug concentration)

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12
Q

Clearance

A

CL = (rate of elimination of drug) / (plasma drug concentration)

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13
Q

Half-life

A

t1/2 = 0.7 x Vd/CL

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14
Q

Loading dose

A

LD = Cp x Vd/F

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15
Q

Maintenance dose

A

MD = Cp x CL/F

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16
Q

Cardiac output

A
CO = stroke volume * heart rate 
CO = Rate of O2 consumption/(arterial O2 content - venous O2 content)
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17
Q

Mean arterial pressure

A
MAP = cardiac output * total peripheral resistance
MAP = 1/3 systolic + 2/3 diastolic
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18
Q

Stroke volume

A

SV = end diastolic volume - end systolic volume

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19
Q

Ejection fraction

A

EF = (stroke volume / end diastolic volume) x 100

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20
Q

Resistance

A
R = driving pressure/flow
R = 8η (viscosity) x length / (∏r^4)
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21
Q

Net filtration pressure

A

Pnet = (Pc - Pi) - (?c -?i)

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22
Q

Glomerular filtration rate

A

GFR = U inulin x (V/ P inulin) = C inulin

23
Q

Glomerular filtration rate (In terms of hydrostatic & oncontic pressures)

A

GFR = Kf [(P GC - P BS) - (? GC - ? BS)]

24
Q

Effective renal plasma flow

A

ERPF = U PAH x (V/ P PAH) = C PAH

25
Q

Renal blood flow

A

RBF = RPF / (1 - Hct)

26
Q

Filtration fraction

A

FF = GFR/RPF

27
Q

Physiologic dead space

A

VD = VT x [(PaCO2 - PeCO2) / PaCO2]

28
Q

Sensitivity

A

Sensitivity = TP / (TP + FN)

29
Q

Specificity

A

Specificity = TN / (TN + FP)

30
Q

Positive predictive value

A

PPV = TP / (TP + FP)

31
Q

Negative predictive value

A

NPV = TN / (TN + FN)

32
Q

Relative risk

A

[a/(a+b)]/[c/(c+d)]

33
Q

Attributable risk

A

[a/(a+b)]-[c/(c+d)]

34
Q

Number needed to treat

A

1/absolute risk reduction (ARR)

1/[Event Rate (control) - Event Rate (treatment)]

35
Q

Number needed to harm

A

1/attributable risk (ARI)

1/[Event Rate (treatment) - Event Rate (placebo)]

36
Q

Hardy-Weinberg equilibrium

A

p^2 + 2pq + q^2 = 1

p + q = 1

37
Q

Henderson-Hasselbalch equation

A

pH = pKa + log ([HCO3-]/ 0.03 PCO2)

38
Q

Volume of distribution

A

Vd= (amount of drug in the body) / (plasma drug concentration)

39
Q

Clearance

A

CL = (rate of elimination of drug) / (plasma drug concentration)

40
Q

Half-life

A

t1/2 = 0.7 x Vd/CL

41
Q

Loading dose

A

LD = Cp x Vd/F

42
Q

Maintenance dose

A

MD = Cp x CL/F

43
Q

Cardiac output

A
CO = stroke volume * heart rate 
CO = Rate of O2 consumption/(arterial O2 content - venous O2 content)
44
Q

Mean arterial pressure

A
MAP = cardiac output * total peripheral resistance
MAP = 1/3 systolic + 2/3 diastolic
45
Q

Stroke volume

A

SV = end diastolic volume - end systolic volume

46
Q

Ejection fraction

A

EF = (stroke volume / end diastolic volume) x 100

47
Q

Resistance

A
R = driving pressure/flow
R = 8? (viscosity) x length / (?r^4)
48
Q

Net filtration pressure

A

Pnet = (Pc - Pi) - (?c -?i)

49
Q

Glomerular filtration rate

A

GFR = U inulin x (V/ P inulin) = C inulin

50
Q

Glomerular filtration rate (In terms of hydrostatic & oncontic pressures)

A

GFR = Kf [(P GC - P BS) - (? GC - ? BS)]

51
Q

Effective renal plasma flow

A

ERPF = U PAH x (V/ P PAH) = C PAH

52
Q

Renal blood flow

A

RBF = RPF / (1 - Hct)

53
Q

Filtration fraction

A

FF = GFR/RPF

54
Q

Physiologic dead space

A

VD = VT x [(PaCO2 - PeCO2) / PaCO2]