epoxides Flashcards
1
Q
alcohol with LG
A
NaH(strong base)
2
Q
Alkene
A
MCPBA
3
Q
Alkene
A
- Br2, H2O, 2. NaOH
4
Q
open up epoxide
A
use H2SO4, and some alcohol, Ch2Ch3OH –> OCH2CH3 adds, alcohol on other side (nucleophile is in more substituted side)
5
Q
alternatively open up epoxide
A
NaOCH2CH3, H3O+, 2. dil NH4Cl (acid, anything to protonated) → epoxide turns into o- anion turns into alcohol , nuc attackes less subsituted