epoxides Flashcards

1
Q

alcohol with LG

A

NaH(strong base)

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2
Q

Alkene

A

MCPBA

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3
Q

Alkene

A
  1. Br2, H2O, 2. NaOH
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4
Q

open up epoxide

A

use H2SO4, and some alcohol, Ch2Ch3OH –> OCH2CH3 adds, alcohol on other side (nucleophile is in more substituted side)

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5
Q

alternatively open up epoxide

A

NaOCH2CH3, H3O+, 2. dil NH4Cl (acid, anything to protonated) → epoxide turns into o- anion turns into alcohol , nuc attackes less subsituted

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