Epithelium Flashcards

1
Q

What are the four basic types of tissues in the human body?

A

Epithelial, connective, nervous, and muscle tissues.

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2
Q

What is epithelial tissue, and where is it found?

A

Epithelial tissue consists of closely packed cells forming layers that cover body surfaces, line cavities, and form glands.

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3
Q

How is epithelial tissue classified by the number of cell layers?

A

Simple epithelium (one layer), stratified epithelium (multiple layers), and pseudostratified epithelium (appears layered but is single).

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4
Q

What are the shapes of epithelial cells, and where might you find each type?

A

Squamous: flat, found in lungs.

Cuboidal: cube-shaped, found in kidney tubules.

Columnar: tall, found in the intestines.

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5
Q

Describe the function and location of simple squamous epithelium.

A

It allows diffusion and filtration, found in alveoli and blood vessels.

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6
Q

What is the main function of simple cuboidal epithelium, and where is it located?

A

Its main functions are secretion and absorption, located in glands and kidney tubules.

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7
Q

How does simple columnar epithelium appear under a microscope, and what are its functions?

A

Appears as a single layer of tall cells with nuclei near the base, functions in absorption and secretion, found in the intestines.

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8
Q

What are pseudostratified epithelia, and where are they commonly found?

A

They appear multi-layered but are single-layered; found in the respiratory tract.

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9
Q

Differentiate between keratinized and non-keratinized stratified squamous epithelium.

A

Keratinized: found in the skin, provides protection and water resistance.
Non-keratinized: found in moist areas like the mouth and esophagus, protects against abrasion.

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10
Q

Where is stratified cuboidal epithelium typically found, and what is its main function?

A

Found in ducts of sweat glands and salivary glands, its main function is protection and some excretion.

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11
Q

What is the function of transitional epithelium, and where is it located?

A

Allows for stretching, found in the urinary bladder.

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12
Q

Name and describe three surface specializations found in epithelial cells.

A

Microvilli: increase surface area for absorption, found in intestines.

Cilia: move substances across cell surfaces, found in respiratory tract.

Stereocilia: longer, for absorption, found in epididymis.

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13
Q

What are tight junctions, and what role do they play in epithelial cells?

A

They seal adjacent cells to prevent leakage, found near the apical surface of cells.

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14
Q

What are gap junctions, and why are they important?

A

They allow the transfer of ions and small molecules between cells, enabling communication.

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15
Q

How do desmosomes support epithelial tissue?

A

They provide strong adhesion between cells, helping the tissue withstand mechanical stress.

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16
Q

Explain the function of hemidesmosomes in epithelial cells.

A

Hemidesmosomes anchor epithelial cells to the basement membrane, providing stability.

17
Q

What is the basement membrane, and why is it essential?

A

A thin layer supporting epithelial cells, anchoring them and regulating molecule movement.

18
Q

Describe the structure and function of ciliated columnar epithelium.

A

Single layer of columnar cells with cilia, found in the uterine tube, moves mucus or particles.

19
Q

Which epithelial tissue types are most protective, and where are they found?

A

Stratified squamous (skin, esophagus) and transitional epithelium (urinary tract) are most protective.

20
Q

What are some diseases associated with epithelial cell junctions?

A

Diseases include psoriasis (skin inflammation) and Darier disease (impaired desmosomes).

21
Q

What are the main types of epithelial tissue?

A

The main types are simple (single cell layer) and stratified (multiple cell layers) epithelium, each further classified by cell shape as squamous, cuboidal, or columnar.

22
Q

How is epithelial tissue classified by function?

A

Epithelial tissue is classified as surface epithelium (covering/lining surfaces and cavities) and glandular epithelium (specialized for secretion, found in glands like the thyroid and sebaceous glands).

23
Q

How does the type of epithelium relate to its function?

A

Simple squamous: diffusion/filtration (e.g., alveoli).

Simple cuboidal: secretion/absorption (e.g., kidney tubules).

Simple columnar: absorption/secretion (e.g., intestines).

Stratified squamous: protection (e.g., skin).

Transitional: allows stretching (e.g., bladder).

24
Q

What are the main epithelial surface specializations, and their functions?

A

Cilia: movement of substances across the surface (e.g., respiratory tract).

Microvilli: increase surface area for absorption (e.g., intestines).

Stereocilia: long, immotile, for absorption (e.g., epididymis).

Flagella: movement, seen in sperm cells.

25
Q

What are the main types of cell junctions in epithelial tissue?

A

Tight junctions: seal cells together, control molecule passage.

Adherens junctions: link the cytoskeleton of adjacent cells.

Desmosomes: strong intermediate filament coupling.

Gap junctions: allow exchange of ions and small molecules.

Hemidesmosomes: attach cells to the basal lamina.

26
Q

How do cell junctions impact disease spread?

A

Tight junctions can be compromised by pathogens like Clostridium perfringens, leading to infections. Inhalation of allergens from dust mites can damage these junctions, causing asthma.