Episcleritis/Scleritis Flashcards

1
Q

What is shown?

A

Nodular Episcleritis

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2
Q

What is this?

A

Diffuse Scleritis

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3
Q

What is this an example of?

A

Scleral Thinning

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4
Q

What is this?

A

Nodular Scleritis

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5
Q

How do the vessels run in the episclera?

A

Straight vessels in a radial configuration

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6
Q

What is this?

A

Scleromalacia Perforans

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7
Q

What is slcera made of?

A

Highly organized collagen, elastin, glycoproteins and proteoglycans

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8
Q

What innervates the sclera?

A

Short and long ciliary nerves

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9
Q

What vessels blanch easily with phenylephrine?

A

Superficial episcleral plexus vessels

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10
Q

Which plexus is most affected in slcleritis?

A

Deeper episcleral plexus

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11
Q

What are the two types of episcleritis?

A

Simple - most common

Nodular

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12
Q

What are the types of slceritis anterior?

A

Non-necrotizing (95%)

  • Diffuse (90%)
  • Nodular (5%)

Necrotizing (5%)

  • w/inflammation
  • w/o inflammation (scleromalacia perforans
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13
Q

2/3 of episcleritis is ___.

A

Idiopathic

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14
Q

When in episcleritis most common?

A

Spring and fall - don’t confuse with allergic conjunctivitis

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15
Q

What is the general presentation of episcleritis?

A

Mild, transient, recurrent, idiopathic inflammation

Often bilateral and sectoral

Symptomes may be none to moderate (some pain from nodular)

Typically sectoral, but may be diffuse

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16
Q

Episcleritis is ___ and generally lasts ___.

A

Self-limiting

2-21 days

Nodular variety takes longer

17
Q

What are the common treatments for episcleritis?

A

Often none

In nodular you may use:

Artificial tears

Topical steroid

Topical NSAID

18
Q

If phenylephrine causes the hyperemia to dissipate, what is the probable disease?

A

Episcleritis

19
Q

What are the signs/symptoms of diffuse episcleritis?

A

Redness followed by aching and pain

-Boring pain may radiate to brow, forehead, ear, jaw and temple

Nocturnal pain wakes patient; improves during day

Redness commonly starts in superior temporal quadrant

Intense red/purple hue with deep plexus injection

*Tender to palpation

Lacrimation, photophobia

*Bliateral 50%

20
Q

At what age does diffuse scleritis usually occur?

A

45-60 , but very rare overall

50% have underlying disease

21
Q

What is seen with scleral thinning?

A

Underlying dark uveal pigment becomes visible

22
Q

Recurrence of ___ scleritis is common.

23
Q

20% of nodular scleritis may progress to ___.

A

Necrotizing

24
Q

Many patients with nodular scleritis have previously had what?

A

HZV of the eye

25
What signs/symptoms describe nodular scleritis?
Insidious onset of pain Redness, tenderness, nodule
26
Which form of scleritis is the most aggressive?
Necrotizing
27
What happens to the sclera with necrotizing scleritis?
It becomes transparent
28
What percent of necrotizing scleritis is bilateral?
60%
29
Which of the scleritises has the strongest association with systemic disease?
Necrotizing
30
What other diagnoses may look like necrotizing scleritis, but aren't?
Malignant melanoma inflammatory syndrome Squamous cell carcinoma of limbus
31
What disease is associated with: Discomfort or pain disproportionate to the severity of orbital inflammation Tender to palpatation No photophobia
Posterior scleritis
32
What are the associated complications with posterior scleritis?
Papilledema Choroidal folds CME Retinal heme Exudative RD Choroidal effusion Myositis Proptosis
33
What are the treatments for anterior scleritis?
NSAID (for non-necrotizing) Systemic steroid if 3 separate rounds of NSAID fails Immunosuppression if steroids fail, or necrotizing dz