Epinephrine

Question 0

Actions

Answer 0

Alpha effects - peripheral, coronary, renal, and mesenteric vasoconstriction and bronchial arteriole constriction

Beta effects - increased heart rate, myocardial contractility, automaticity of all pacemaker cells

Decreased chemical mediator release during allergic reaction

Lowers ventricular threshold

Question 1

Class

Answer 1

Sympathomimetic/ Natural Catecholamine

Question 2

Indications

Answer 2

Acute asthma attacks

severe allergic reaction

Anaphylactic shock

Cardio arrest

Question 3

Contraindications

Answer 3

Narrow angle glaucoma

Hypovolemic shock

Hypertension

Question 4

Dosage

Answer 4

Adult:
Cardiac - 1mg IV push of 1:10,000 solution every 3-5min

Asthma/ Allergic Rx/ Anaphylaxis - 0.3-0.5 mg SQ of 1:1,000 solution, may be repeated in 20min - in severe cases, 0.3-0.5mg 1:10,000 IV may be administered

Peds:
Cardiac arrest - 1st IV or IO dose is 0.01 mg/kg of a 1:10,000 solution. Repeat dose is 0.1 mg/kg 1:1,000 diluted w/5-10ml saline

Asthma/ Allergic Rx/ Anaphylaxis - 0.01 mg/kg SQ of 1:1,000 solution (max single dose 0.3mg), may be repeated in 20 min
- in severe allergic Rx 0.01 mg/kg may be administered IV push slowly

Question 5

Side effects

Answer 5

Hypertension

Tachycardia

Hyperglycemia

Cerebral hemorrhage

Question 6

Considerations

Answer 6

Caution in pregnancy due to decrease placental blood flow

May req repeat dose in 15-20 min when given SQ for asthma

Extreme caution in pts over 40 years old