Epilepsy Medications Flashcards
1
Q
1st line for tonic clonic seizures
A
Valproate
2
Q
1st line for absence seizures
A
Ethosuximide or valproate
3
Q
1st line for myotonic, tonic or atonic seizures
A
Valproate
4
Q
Focal +/- generalised seizure tx
A
Lamotrigine or CBZ
5
Q
Tx in pregnant women?
A
AVOID VALPROATE
Switch to lamotrigine or CBZ
+ folic acid supplements if child-bearing age
6
Q
Non-medication treatment options?
A
Vagal nerve stimulation
Neurosurgical resection if epileptogenic focus identified
Ketogenic diet
7
Q
Enzyme inducers
A
CBZ
PHE
barbiturates
8
Q
Enzyme inhibitors
A
Valproate
9
Q
Side effects of lamotrigine
A
Rash, hypersensitivity
SJS
Diplopia
Enzyme inducer drug interactions
10
Q
Side effects of valproate
A
ALRPOATE A ppetite increased (weight gain) L iver failure P ancreatitis R eversible hair loss O edema A taxia T eratogenicity, tremor, thrombocytopenia E ncephalopathy
11
Q
Side effects of CBZ
A
Agranulocytosis/leukopenia
Skin reactions
Diplopia
SIADH
12
Q
Side effects of phenytoin
A
Gingival hyperplasia/hypertrophy Hirsutism Cerebellar syndrome (ataxia, nystagmus, dysarthria) Peripheral sensory neuropathy Diplopia Tremor
