Epilepsy- Dr. Takeda Flashcards
Lamotrigine, Levetiracetam, Topiramate, Valproic acid, Ethosuximide, Rufinamide can all be used to treat what kind of seizures?
-Generalized seizures
Lamotrigine, Levetiracetam, Gabapentin, Pregabalin, Carbamazepine, Oxcarbazepine, Topiramate, Valproic acid, Phenytoin, can all be used to treat what kind of seizures?
-Focal Seizures
Lamotrigine, Levetiracetam, Topiramate, Valproic acid can be used to treat what types of seizures
-Both Focal and Generalized seizures
Which drug is first line for Lennox-Gastaut Syndrome
-Rufinamide
Which drug is fist line for Absence seizures
-Ethosuximide
Inhibitory Synapses
- Increased Cl- inward
- GABA
Excitatory synapses
- Increased Na+ or Ca++ current inward
- Glutamate
Vigabatrin MoA
- Inhibits GABAT
- Increasing GABA concentrations
Which AEDs are contraindicated in pts with a history of kidney stones
- Topiramate
- Zonisamide
- Acetazolamide
What do you do with psych related issues due to keppra?
-Supplement with vitamin B6
Side effects of phenytoin
- Nystagmus
- Gingival hyperplasia
Side effects with Carbamazepine and Oxcarbazepine
- Hyponatremia
- Skin rash (HLA-B*1502)
Vigabatrin side effects
-Vision loss
Which AEDs can cause weight gain
- Valproic acid
- Gabapentin
- Pregabalin
Which AEDs can cause weight loss
- Topiramate
- Zonisamide
