Epilepsy: causes and treatment Flashcards

1
Q

What is a seizure

A

A transient occurrence of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain

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2
Q

What causes different type of epileptic symptom

A

Some seizures occur in different networks of cerebral neurons

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3
Q

What is epilepsy

A

A pathological and enduring tendency to have recurrent seizures and by the neuro-biologic, cognitive, psychological and social consequences of this condition

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4
Q

Why does seizure type matter

A

Seizure type often determines treatment

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5
Q

What are the two main type of seizures

A

Generalised seizures- starts simultaneously in both hemispheres

Focal seizures- Seizure starts in a focus and then spreads

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6
Q

What are the 3 subtypes of common generalised seizures

A

Typical absence

Myoclonic

Tonic-clonic

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7
Q

When do Absence seizures start

What are symptoms

A

Childhood

Sudden loss and return of consciousness
Flickery eye movements
Some Involuntary movement
Frequent brief attacks (1-30s)

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8
Q

What do Absence Seizures respond to

A

Some anti-epileptic drugs and not others

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9
Q

What does the EEG in an absence seizure look like

A

Spike and wave pattern

Occur at frequency of 3Hz

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10
Q

What is a Myoclonic seizure like

When is it worse

A

Sudden, brief, shock-like muscle contractions (Myoclonic jerk)

Usually bilateral arm jerks

Define certain Epilepsy syndromes

–>Often worse in mornings

–>Precipitated by sleep deprivation and alcohol

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11
Q

What do Myoclonic seizures respond to

A

Particular anti-epileptics

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12
Q

What are the features of Tonic-CLonic seizures

A

Sudden onset, gasp, fall

Tonic phase with cyanosis

Clonic phase

Post-ictal phase

Tongue bitten and incontinence

Noisy breathing

Headache and muscle pain afterwards

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13
Q

What are types of uncommon generalised seizures

what are they usually associated with

A

Atypical absence

Tonic

Atonic

–>Severe epilepsy

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14
Q

What are symptoms of atonic seizures

A

Sudden dropping
Limp and unconscious
Only lasts a split second

More common in children with severe epilepsy

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15
Q

What is first seen in a focal seizure that starts in motor area

A

Twitching or jerking

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16
Q

What is first seen in a focal seizure that starts in a visual area of brain

A

Coloured lights

17
Q

What happens as a focal seizure spreads

A

Loss of awareness and involuntary movement

18
Q

What are focal seizures often caused by

A

Brain lesions

19
Q

What is the most common type of Temporal Lobe seizures

A

Temporal Lobe Seizures

20
Q

What are the Auras of a Temporal Lobe Seizure

What are symptoms as it spreads

A

1) Rising sensation in stomach
2) Olfactory and gustatory hallucinations
3) Deja vu

  • Suddenly stops and blank stares
  • Loss of responding and awareness
  • Mouth movements
  • Fidgeting or postures-automatisms
21
Q

Symptoms of a focal seizure becoming tonic-clonic

A

(tonic) Body goes stiff. (clonic) Then your limbs jerk about and you may lose control of bowel or bladder etc

22
Q

What is the epilepsy type of someone having :

  • myoclonus and tonic clonic seizures
  • With generalised EEG findings and normal MRI
  • Onset age 16
A

Juvenile Myoclonic epilepsy

23
Q

What is the epilepsy type of someone having

  • Aura of fear and rising sensation and blank look
  • ONset of 8
  • Focal EEG findings
  • Lesion in left hippocampus on MRI
A

Focal epilepsy: temporal lobe

24
Q

What are signs of idiopathic epilepsy

A

No brain lesions
No intellectual impairment
Often generalised seizures

Easy to treat. Seizures usually controlled

25
Q

What are signs of symptomatic epilepsy

A

Sign og underlyging lesion or brain disorder. Often cognitive problems, abnormal MRI common

Seizures not controlled

26
Q

What is Encephalitis

A

Inflammation of the brain

27
Q

Examples of brain disorders causing seizures

A

Encephalitis
Vascular lesion
Hippocampal scarring
Tumour