Epilepsy

Question 1

Phenobarbitone

Answer 1

barbiturate which binds inside the cl- channel of the GABA receptor to increase duration of opening and cause hyperpolarisation of the trigger cells
low TI and cause induction of the p450 liver enzymes and casues them to metabolise things like contrapceptive pills better which is BAD

Question 2

Hydantoins e.g. Phenytoin

Answer 2

A sodium channel blocker and also increases the activity of the sodium potassium ATPase