EPILEPSY

Question 1

Name the different AED that are CYP34A inducers

Answer 1

Phenytoin 
Phenobarbital (barbuates) 
Carbamazepine 
Oxcarbazepine
Ethosuximide  
Topiramate

Question 2

AED may causes treatment frailer for women taking OCP

true /false

Answer 2

False

Question 3

What is Catamenial epilepsy

Answer 3

seizure before or during menstration

Question 4

what is the effects of barbiturates and phenytoin in pregnancy

Answer 4

congenital heart malformation and facial clefts

Question 5

what is the effect of carbamazepine on pregnancy’s

Answer 5

spina bifida

Question 6

true or fales topramate may cause oral clef in children

Answer 6

true

Question 7

which of the folloing drugs oral contraceptives lower the levels of 
1. carbamazepine 
2 . phenytoin 
3. valporic acid 
4. ethosuximide

Answer 7

3. valporic acid

Question 8

name 3 side effects of vaporic acid

Answer 8

alopecia
hepatitis
irregular mens

Question 9

is valporic acid a CYP3A4 inducer or inhibitor

Answer 9

inhibitor

Question 10

what is the relationship between valproic acid and OCP ?

Answer 10

OCP decreases the effectiveness of Valproic acid

Question 11

what is the deferent between valproic acid and divalproex sodium

Answer 11

there is no difference they are salts

Question 12

patient is currently taking Tegretal for the first time what are your counseling points

Answer 12

patient should look out for rash , itching , dizziness , anemia symptoms , thrombocytopenia,hyponatremia

Question 13

Name five common drugs that increases the level of Carbamazepine

Answer 13

erythromycin 
clarithromycin 
St. John’s Wort 
diltiazem, 
Verapamil

Question 14

what are the most common side effects of Phenyton

Answer 14

folate deficiency

Question 15

phenytoin are inducers or inhibitors of CYP3A4 ?

Answer 15

inducers -

Question 16

name 3 common side effects of gabapentin

Answer 16

dryness of mouth, 
constipation,
blurred 
vision 
drowsiness

Question 17

what is the maximum does for gabapentin

Answer 17

2400mg