Epigenetic's Flashcards

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1
Q

Epigenetic’s

A

Addition of chemical tags (methyl or acetyl groups) to DNA that activate or inactivate genes, adjusts our minds and bodies in response to life experiences

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2
Q

Gene Imprinting

A

The differential silencing of gamete genes by males and females, genders imprint differently

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3
Q

Methylation of Cytosines by DNA

A

Can increase or decrease gene expression, which is how cells differentiate during development, proves how stress and other environment factors can change gene expression

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4
Q

Histone Acetylation

A

Unwinds regions of DNA to facilitate transcription

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5
Q

Histone Deacetylation

A

DNA winds tighter, inhibiting transcription

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6
Q

Epigenetic Carcinogens

A

Compounds that affect histones or methylation, includes DES, hexachlorobenezene, Ni+, and cadmium

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7
Q

Parental Conflict Hypothesis

A

Says father is more interested in growth of offspring at the expense of mom, whereas mom has to balance her own and the offsprings survival

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8
Q

Paternally Imprinted Genes

A

Tend to be oncogenes that are growth promoting

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9
Q

Maternally Imprinted Genes

A

Tend to be tumor suppressor genes that slow growth

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10
Q

Epigenetic Inheritance

A

Some epigenetic changes are heritable, it used to be though that new embryo’s epigenome was completely erased and rebuilt from scratch

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11
Q

What does abuse of mom during pregnancy cause

A

Epigenetic changes in kids cortisol receptor genes

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12
Q

Moms hi stress during kids 1st year causes

A

139 epigenetic changes in the kid

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13
Q

Dads hi stress during kids pre-school years causes

A

31 epigenetic changes in daughters

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14
Q

Mom and Dads stress effects

A

Moms stress effects both boys and girls, but dads stress only effects girls

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15
Q

Dads absence or lack of participation is associated with

A

Early puberty and difficult temperamental traits in girls, but not boys

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16
Q

Drugs of abuse trigger

A

epigenetic changes in the brain, affecting hundreds of genes, not shown to be heritable, suggesting long term use may be written in epigenetic code

17
Q

Starvation

A

Causes transgenerational epigenetic changes, kids and grandkids of starved people tend to be born smaller, have higher rates of diabetes, heart disease and mental disorders