Epidemiology/ Study types Flashcards
What is epidemiology?
The study of the distribution and determinants of
health-related states or events in specified
populations, and the application of this study to the
control of health problems.
Descriptive vs analytical epidemiology
Descriptive:
* Describes occurrence of disease
* Determinants within a population
Analytical:
* Explores the quality and amount of influence that determinants have on the occurrence of disease.
* Explores “how” health events occur
* Usually through studies with group comparisons
What is a cross sectional study (prevalence study)
Observational study that looks at the relationship between health related characteristics and other variables of interest withiin a defined population at one particular time.
What is a case control study
Observational study that looks at persons with a disease or condition and a suitable control group of persons without the condition, and comparing how frequently a suspected attribute or risk factor is present in each group.
What is a cohort study (incidence study)
Observational study that follows 2 groups of people those with and those without an exposure over time, comparing how frequently an outcome occurs in each group.
4 examples of factors that can impact health outcomes
Innate factors, acute factors, chronic factors, time-varying factors
Prevalence is..
The proportion of the population that has disease at a
particular time
Incidence risk is..
is the total number of new cases divided by the population at risk
at the beginning of the observation period
Sources of bias
Selection bias, attribution bias, observer bias, procedure bias, response bias, misclassification bias.
Advantages of cross sectional studies
- rapid generation of data
- multiple variables at time of snapshot
- easy to conduct, cheap
Disadvantages of cross sectional studies
- cant analyse over time
- Cant determine cause and effect
- timing is not representative
- inefficient for rare diseases
- prone to bias
Relative risk formula
RRR = IRunexposed – IRexposed / IR unexposed
(IR-incidence rate or relative risk)
Absolute risk formula
ARR = IRunexposed – IRexposed
(IR-incidence rate or relative risk)