Epidemiology of Ischaemic Heart Disease

Question 1

Public Health Significance of CV Disease

Answer 1

Leading cause of mortality in developed countries
Rising tendency in developing countries
Major impact on life expectancy
Sig contributes to morbidity and death rate in middle aged population

Economic cost
Morbidity: nearly 30% of all disability patients

Question 2

Main types of CV Disease

Answer 2

Coronary Heart Disease
Cerebrovascular Heart Disease
Hypertensive Heart Disease

Peripheral Vascular Heart Disease
Rheumatic Heart Disease
CMPs

Question 3

Mechanism of Ischaemic Heart Disease

Answer 3

Lipid Theory: lipid accululation

Blood Coagulation Theory: Microthrombi due to injury

Blood vessel wall injury: Due to shearing stress

Monoclonal Theory: proliferating cell accumulates

Immunological theory: Ab damage endothelium