Epidemiology and Risk Factors Flashcards
Condiciones englobadas en CVD (7)
CAD, HF, VHD, stroke, congenital heart heart defects, rhythm disorders and sudden cardiac arrest.
Factores de riesgo modificables de CVD / 7 metrics of CV health
Dyslipidemia Smoking DM Hypertension Obesity Inadequate exercise Diet
Abandono de tabaco y reducción de riesgo CV
Reduces CV risk within 2 years with risk returning to the level of a nonsmoker after approximately 10 years
Smoking and CV risk
Overall mortality is increased two to three times, and risk for stroke is increased two to four times.
Consumo recomendado de frutas y verduras
1.5 a 2 tazas de fruta
2-3 tazas de verduras
History of premature CAD
Male < 55 years
Female < 65 years
In parents doubles risk for MI in men and increases risk in women by 70%
CV risk scores
Framingham = Used to estimate the 10 years risk for a major coronary heart disease event (<10% low, 10-20% intermediate and >20% high) / A limitation is it’s underestimation of risk in women and minority populations.
Reynolds risk score = Sex specific score for both men and women that includes family history and hs-C reactive protein levels.
ACC/AHA - ASCVD risk estimator = Identify who would benefit from preventive measures, including statin therapy
Treatment of hypertension reduces risk for …
Stroke, heart failure and CKD
Diferencia entre mujeres y hombres en CVD
- Mortalidad dentro del primer año después de un primer IAM es más alto en mujeres (26%) que en hombres (19%)
- Mujeres tienen más alto riesgo de EVC
- Dislipidemia, DM, obesidad y tabaquismo confieren mayor riesgo para CAD en mujeres
- Mujeres cursan mayormente con síntomas atípicos de angina, retrasando Dx’s
- Mujeres con NSTMI tienen peores resultados (alta frecuencia de sangrado, HF, shock, kidney failure, stroke and reinfarction)
Metabolic syndrome
Presencia de al menos 3 de los siguientes:
- Glucosa elevada
- Obesidad central
- HDL baja
- TGL altos
- TA alta
CAD and diabetes
CAD is more extensive and the incidence of multi vessel disease is increased
CAD and CKD
Risk for CVD related death is 5-30 times higher in patients undergoing dialysis
Microalbuminuria independently increases the risk for CV events
Patients undergoing hemodialysis do not benefit from secondary prevention with STATINS