Epidemiology Flashcards
Bradford Hill Criteria for Casuality
Strength of Association Consistency Temporality (exposure must precede occurrence) Biological Gradient Plausibility Coherence Analogy Specificity Experimental Evidence
Prevalence
Number of existing cases in a population exhibiting a disease or condition at a specified time or period
Point: proportion at a specific point in time
Period: proportion with pre-existing cases and new cases during period
Proportion
Dividing one quantity by another
Numerator included in the denominator
Incidence
Number of new cases of disease or condition which occur in a given time period in a population
Need initial and final examination
Cumulative: proportion of subjects under the study that get disease under observation
Ratio
Dividing one quantity by another
Numerator not in the denominator
Prevalence, ratio or proportion?
Proportion
Incidence, ratio or proportion?
Ratio
Except: cumulative incidence is proportion
Relative risk
Measure of association in cohort studies, incidence can be measured in them
How common disease is among those exposed
How many times more common or less common is measure of disease frequency in population
Interpret Relative Risk
RR = 1. (Null)
RR > 1. (Increases risk)
RR <1. (Decreases risk)
Odds Ratio
Measure of association in case-control and cross-sectional studies, indirect estimate of the relative risk
How common is exposure in those diseased
Odds ratio interpretation
OR = 1 (null)
OR > 1 (exposure common)
OR < 1 (exposure uncommon)
Attributable risk
Absolute risk difference or the percentage of cases due to a given exposure
How much does it actually do
Attributable proportion
Proportion of people who developed disease due to exposure
Bias
Systematic error in conduct of study leading to an incorrect association estimate, not valid
Selection Bias
Study groups are not comparable