EPIDEMIOLOGY Flashcards
Study of diseases in population
Epidemiology
John M. Last
Defined Epidemiology
Most common cause of diarrhoea in India ?( Winters)
ROTAVIRUS
Malaria vector ( Rural)?
Anopheles Culcifacies
Malaria vector ( Urban)
ANOPHELES STEPHENSI
Dengue Vector
AEDES AEGYPTI
Tiger mosquito
AEDES AEGYPTI
Droplet size that transmits most efficiently?
<5
Interpersonal distance where transmission is max?
<1 meter
Road traffic accidents occur more in which season?
Rainy and winter
Most common element deficiency in himalayan
Boron
Most common cause of mental retardation in India?
Down syndrome
Most common cause of hypothyroidism in India?
Autoimmune disorder ( Hashimoto Thyroiditis)
Kala azar
Phlebotomous
UP, west bengal, bihar , jharkhand
Kala azar
Sandfly
Kala azar
Japanese Encephalitis
Culex Triteniorhyncus
Found in all states of India but most commonly found in UP and WB
Japanese Encephalitis
CULEX VISHNUII
Japanese Encephalitis
Culex gelidus
Japanese Encephalitis
Hard Tick
Kyasanur Forest Disease
Haemaphysalis spinigera
Kyasanur Forest Diaease
Nortt east and east india
Malaria
Monkey Disease
Kyasanur Forest Diaease
Culex Quinquefasciatus
Filariasis
Coastal region of india
Filariasis
Yellow Fever Vector?
AEDES AEGYPTI
Monkey pox
Manali
Zika virus
Gujrat( AEDES)
Culex pipens ( kerala)
West Nile fever
Measles
6 months to 3 years
5-9 yrs
Mumps
5-15 yrs
Rheumatic fever
Neonatal pneumonia
0-28 days
Infant
0-1 yr
Child
0-18yrs
10-19yrs
ADOLESCENT
Geriatrics
> 60 yrs old
Perinatal period
28wks POG till 7 days post delivery
POG>28 wks
BW> 1000gms
BL>35 cm
Abortion
Period of viability
POG<28 wks
BW<1000gms
BL< 35 cm
Most sensitive criteria to assess abortion
Birth weight> 35 cm
Forward
Cohort study
Case control
Backward
Strength of association for cohort study is given by?
Relative Risk
RR=1
No association
Risk factor is protective
RR=<1 Negative/ Inverse Association
RR> 1
Association Present
Prospective Study
Cohort study
Exposure to outcome study
Cohort study
Follow up/ Incidence Study
Cohort study
Cause to effect
Cohort study
Exposure to outcome study
Cohort study
Most popular cohort study
Framingham heart study
Odds Ratio
Case control study
Case reference study
Case control
Effect to cause study
Case control study
Disease to Risk factor study
Case control
Retrospective study
Case control study
Backward looking
Case control study
Recall bias
Case control
Maximum allowable attrition rate
<5%
Ideal retention rate
> 95%
Any factor associated both with exposure and outcome
Confounding
Confounding can be removed by?
Matching
Systematic error
Bias
Best blinding
Triple blinding
Common type of Blinding
Double blinding
Study based on primary data
Cross sectional study
Used in nutritional surveys
Ecological study
Based on secondary data
Ecological study
Results of study applicable on individual
Cohort, Case Control, Cross Sectional
Results of Study applicable on population
Ecological Study
Randomised controlled trial Unit
Patient/Cases
Selection bias in RCT is removed by ?
Randomisation
Heart of RCT?
Randomisation
In which phase
Maximum tolerated dose is tested?
Phase 1
Maximum drug failure is seen in?
Phase 2
RCT is done in which phase
Phase 3
Post marketting surveillance is done in which phase?
Phase 4
Theroy of spontaneous generation
Aristotle
Germ theory of Disease
Louis Pasteur
Patten Koffer
Multifactorial causation of Disease.
Web of causation
MCMohan & Pugh
Agent
Host
Environment
Epidemiological Triad
Agent
Host
Environment
Epidemiological Triad
Agent
Host
Environment
Time
Epidemiological Triangle
Advanced model of epidemiological Triangle
Agent is replaced by causative factors
Advanced model of epidemiological Triangle
Environmental factors
Genetic factors
psychological factors
Nutrition
Father of epidemiology
John snow
Father of medicine
Hippocrates
First true epidemiologist
Hippocrates
Father of public health
Cholera
First distinguished epidemiologist
Syndenham
Father of modern epidemiology
John snow
(New +old case/ total population)×100
Prevalence
(New case/ total population)× 100
Incidence
Prevalence study is
Cross sectional
Covaxin
Killed vaccine
Hep A
Killed
Hep B
Recombinant
At birth vaccines given are?
BCG
OPV 0
HEP B
9 months vaccines given are
Measles 1/MR1
Vitamin A(1lakj IU)
JE live 1
PCV BOOSTER
FIPV3
16-24 months
DPTB
OPVB
Measles 2
MR2
JE live 2
Which vaccines are contraindicated in fever
Typhoid vaccine
COVID 19 vaccine
Observation period after administration of vaccine?
30 min
Vaccine that causes paralysis
OPV
Vaccine that causes Hypersensitivity and shock ?
Hep B
Measles vaccine causes?
Toxic shock syndrome
Life threatening complication of rota virus?
Intussusception
Killed Influenza vaccine causes
Killed swine flue vaccine
Gullien Barry Syndrome
Vaccine that causes fever
Pertussis/ DPT
Measles vaccine can cause
Febrile seizures
Hypotensive hyporesponsive episode is seen in which vaccine
Pertussis / DPT
Persistent inconsolable crying
Pertussis / DPT
Osteomyelitis
BCG
Lymphadenopathy
BCG
Tetanus toxoid vaccine in pregnancy causes ( pg neet)
Brachial neuritis
Thrombocytopenia is caused by which vaccine?
MMR
Temperature of cold chain
+2°C to 8°C all vaccines
Vaccine carrier
4 icepacks
16-20 vials
12-24 hrs
Open vial policy
Can be used upto 28 days
Thai updated Red cross Regimen of rabies vaccine
2-2-2-0-2
Essen regimen of rabies vaccine include
1-1-1-1-1
Cervarix
Bivalent
Gardasil
Quadrivalent
Vaccine given in 10 yrs of age?
Tetanus Diphtheria ( Td)
Strain of BCG vaccine ?
Danish 1331
Paralysis
Opv
Hypersensitivity &shock
Hep B
Toxic shock syndrome
Measles