Epidemiology Flashcards
Study of distribution and determinants of disease frequency in human population
Epidemiology
Backbone of disease prevention
Epidemiology
First to employ quantitative methods in describing population vital statistics
John Graunt
Investigated a cholera epidemic in mid 19th century London
John Snow
Discovered that some diseases are caused by living organisms
Koch
Study where risk factors for coronary heart disease where discovered
Framing Heart study
Discovered polio vaccine
Salk
Discovered the association between smoking and lung cancer
Doll and Peto
3 sectors of the wheel causation
Biological
Social
Physical
Prevalence study is also called
Cross sectional
Ecological study is also called
Correlational
Diseases and age patterns
Magnitude decreases with age
Long lasting immunity
Diseases and age patterns
Magnitude increases with age
Degenerative diseases
Temporal variation where there is long term fluctuation of disease occurrence over many decades
Secular trend
Temporal variation where increases in number of cases more or less regularly every around 5 years due to accumulation of susceptible through births
Cyclic intrinsic variation
Varicella is an example of what type of temporal variation?
Cyclic intrinsic
Temporal variation where fluctuations of disease occurrence during a year reflecting climactic changes
Seasonal variation
Most basic descriptive study design that consists of a brief report on the characteristics or outcome from a single clinical subject or event
Case report
A study or survey of a defined population at a specified point in time on a topic or variables of interest
Cross sectional
Economical
Convenient for sudden outbreaks
Not suitable for rare or acute disease
Difficult in interpreting temporal sequence of cause and effect
Cross sectional (descriptive)
Inferential statistics used for case control study
Odds ratio
Used to investigate rare diseases and diseases with long lag or long period of latency
Case control
Inferential statistics used for cohort
Relative risk ratio
Study that provides the best information about disease causation
Cohort