EOR Topics to Review Flashcards
What are contraindications to using thrombolytics for stroke treatment?
- TCP < 100,000
- Active bleed
- GI ulcer or bleeding within the last 3 weeks
- Ischemic stroke or MI within the last 3 months
- Known bleeding disorder
- Major surgery (intracranial or intraspinal) within the last 3 months
- History of ischemic stroke
- INR > 1.7, PT > 15 s, aPTT > 40 s while on ACT
- Evidence of hemorrhage on imaging
- SBP must be < 185, DBP must be < 110
Description of subdural vs epidural hematoma on imaging
Epidural: lens/lemon shaped hyperdensity, does NOT cross suture lines
Subdural: crescent shaped hyperdensity, CAN cross suture lines
What is a situation in which you should start empiric therapy for meningitis before doing the lumbar puncture?
Always start empiric therapy after performing a lumbar puncture UNLESS the pt is showing signs of ICP and warrants a head CT –> waiting to start abx post CT delays care too long
What are clinical signs of ICP?
Papilledema (swelling of optic disc on fundoscopic exam)
AMS
Lethargy
Seizures
HA
Peds: high pitched cry, bulging fontanelle
What signals ICP on imaging?
Mass effect (cerebral shifting to one side)
MOI for anterior cord, central cord, and Brown Sequard injuries
Anterior: flexion or ischemia
Central: hyperextension
Brown Sequard: penetrative trauma
Clinical manifestations of spinal cord injuries
Anterior: loss of sensation, pain/temp and motor ability below injury/lesion level, preserved proprioception and vibration
Central: sensory and motor deficits in UE > LE
Brown Sequard: ipsilateral loss of motor, vibration and proprioception at the level of the injury with contralateral loss of pain and temp 2-3 levels below the lesion
MG versus LE pathophys
MG = autoimmune destruction of postsynaptic membrane ACh receptors (WORSE with movement)
LE = destruction of presynaptic membrane ACh receptors (BETTER with movement)
C4/C5 radiculopathy (C5 root) manifestations
Pain - medial scapula, lateral upper arm
Weakness - deltoid, supra/infraspinatus
Sensory loss - lateral upper arm
Reflex loss - brachioradialis, “supinator” reflex
C5/C6 radiculopathy (C6 root) manifestations
musculocutaneous n. involvement
Pain - lateral forearm, thumb, index finger
Weakness - biceps, brachioradialis, wrist extensors
Sensory loss - lateral forearm and thumb
Reflex loss - biceps reflex
C6/C7 radiculopathy (C7 root) manifestations
Pain - medial scapula, posterior arm, dorsum of forearm, third finger
Weakness - triceps, wrist flexors, finger extensors
Sensory loss - posterior forearm, middle finger
Reflex loss - triceps reflex
C7/T1 radiculopathy (C8 root) manifestations
Pain - shoulder, ulnar side of forearm, fifth finger
Weakness - thumb flexors, abductors, intrinsic hand muscles
Sensory loss - fifth finger
Reflex loss - N/A
First line gout treatments
Acute management:
NSAIDs (naproxen, indomethacin) + ice
Colchicine (CI if severe kidney disease)
Steroids (PO or IV prednisone depending on severity, caution in pts with DM)
Chronic management:
Allopurinol
Probenecid (uricosuric, helps increase renal excretion of uric acid)
Kanavel criteria for flexor tenosynovitis
1) Tenderness along the course of the flexor tendon
2) Fusiform or symmetrical swelling of the finger
3) Pain with passive extension
4) Flexed posture of the finger
Flexor tenosynovitis treatment
IV abx (vanco and broad spectrum penicillins)
Olecranon bursitis vs septic arthritis of elbow
Olecranon bursitis – localized swelling of olecranon bursa, not associated with nearly as much erythema, systemic signs of infection or warmth to palpation –> DOES NOT REQUIRE JOINT TAP, treat with NSAIDs
Septic arthritis – swelling, warmth, fever, tenderness to palpation, SIRSy –> REQUIRES JOINT TAP, traet with abx
Muscle sprain treatment of choice
NSAIDs + rest
What physical exam finding is consistent with supraspinatus tendonitis?
Hawkins-Kennedy test – assess impingement
Jobes (empty can) test – best assesses supraspinatus function in isolation
Physical exam findings of AC joint separation versus anterior shoulder dislocation
Anterior shoulder dislocation – loss of rounded aspect of shoulder, externally rotated and slightly abducted, prominent acromion
AC joint separation – tenderness to palpation over AC joint
Which murmur is most associated with rheumatic heart disease/fever?
Mitral stenosis
Describe the findings of mitral stenosis
Mid diastolic, rumbling murmur with an opening snap
How can you distinguish afib with RVR versus SVT on EKG?
Afib with RVR = irregular rhythm
SVT = regular rhythm
First line pharmaceutical mgmt for SVT vs afib with RVR
SVT = adenosine 6 mg IV
Afib with RVR = metoprolol or diltiazem IV (get rate control)
Are murmurs that occur after S2 diastolic or systolic?
Diastolic
Aortic regurg description
Soft, high pitched blowing diastolic murmur best heard at LUSB in 3rd intercostal space, louder/better auscultated when pt is sitting up and leaning forward
What is the #1 risk factor for aortic dissection?
HTN
Aortic regurg most common presentation
Dyspnea, pulmonary edema (bibasilar rales)
What is the BP med of choice in pts with aortic dissection and hypertension?
Esmolol (goal is SBP < 120)
First line antihypertensives in hypertensive emerency for pts with:
- Eclampsia
- Hypertensive encephalopathy
- Pulmonary edema
- Aortic dissection
Eclampsia = magnesium sulfate +/- labetalol, hydralazine
Hypertensive encephalopathy = nicardipine
Pulmonary edema = vasodilators FIRST (nitroglycerin, sodium nitroprusside), can f/u with diuretics after
Aortic dissection = esmolol
What historical factors point more towards cardiogenic etiologies of syncope?
Absence of pre/postdromal symptoms
Syncope with exertion
Murmur on physical exam
Treatment for acute decompensated heart failure
LMNOP
L: lasix (or another diuretic if contraindicated)
M: morphine
N: nitroglycerin drip
O: oxygen if O2 sat < 92% (non rebreather, noninvasive positive pressure ventilation)
P: position head of bed to 30 degrees
NSTEMI/STEMI treatment
Acute mgmt: MOAN + DAPT + anticoagulate + reperfuse
MOAN = morphine for irretractable pain, oxygen if O2 < 92%, aspirin 325 mg crushed, nitroglycerine
DAPT = aspirin + tocagrelor prior to PCI, continue indefinitely (can use clopidogrel in pts with true aspirin allergy)
Anticoagulate = eliquis, xarelto
Reperfusion = PCI
Discharge/long term mgmt: BASH + continuation of DAPT
BASH = beta blocker, ace inhibitor, statin, and heparin
When do you initiate transcutaneous pacing and/or atropine for AV blocks?
If patient is hemodynamically unstable
What is the appropriate chronic treatment for Mobitz II or 3rd degree AV block?
Permanent pacemaker (can admit for observation in asymptomatic Mobitz II patients)
What is the most common cause of acute arterial occlusion?
Thrombus/atrial fibrillation
Hallmarks of thyroid storm
Tachycardia, hyperthermia, hypertension, exophthalmos
6 D’s of dilated cardiomyopathy etiology
Dunno (idiopathic)
Drugs (cocaine, antivirals such as HIV meds)
Disease (viral infection)
Doxorubicin
Deficiency (B12)
Drinking alcohol
V fib treatment algorithm
Early defibrillation + CPR (queue up 1 mg epi IV while machine is getting ready) –> can administer epi q3-5 min
Which of the following is most consistent with reflex syncope/vasovagal response?
A) Absence of a postdrome
B) Postevent confusion
C) Prodrome with dizziness
D) Provocation with prolonged standing
D
A – c/w cardiogenic syncope
B – c/w seizure
C – c/w cardiogenic syncope or seizure
What are the 2 big stroke mimics?
Hypoglycemia –> ALWAYS GET A POC GLUCOSE IN SUSPECTED STROKE
Aortic dissection –> check distal pulses and BP in both arms
Multifocal atrial tachycardia treatment
Supportive care
+/- oxygenation
Characteristics of LBBB on EKG
W in V1, M in V6, large wide R wave in lead I
pSVT management algorithm
If HDS: Valsalva –> adenosine 6 mg IV –> adenosine 12 mg IV –> cardiovert
If hemodynamically unstable: start with cardioversion
Acute angle closure glaucoma treatment
PO or IV acetazolamide (carbonic anhydrase inhibitor, decreases aqueous humor production), topical timolol or another beta blocker, topical apraclonidine (alpha agonist) + immediate ophtho consult for potential iridotomy
Consider mannitol if refractory to initial medical management
MC pulmonary complication of influenza
Pneumonia secondary to superimposed bacterial infection (MRSA, strep pneumo MC)
Anterior vs posterior epistaxis
Anterior (MC, often seen in kids) = comes from the kiesselbach plexus, less severe bleeding, treat with direct pressure, topical vasoconstrictors (i.e. Afrin aka ozymetazoline), silver nitrate cautery, packing and d/c with orders to follow up for packing removal in 24-48 hours
Posterior = comes from the sphenopalantine artery, report bleeding from b/l nostrils, treat with packing (balloon or foley nasal catheter)
What meds should be avoided in R sided MI?
Vasodilators (i.e. nitro) b/c patients are preload dependent
R sided MI treatment
IV fluids (fluid resuscitation helps avoid hypotension)
Spinal epidural abscess big 5
Etiology: common in immunocompromised (DM) pts, pts with alcohol use disorder or misuse of IV drugs
S/sx: low back pain, fever, loss of bladder/bowel function+/- presence of focal neurologic deficits
Dx: emergent MRI of lumbar spine
Tx: emergent NSGY consultation for drainage and decompression + broad spectrum abx
What calcium level warrants dialysis?
> 18 mg/dL
Cholangitis vs acute hepatitis
Cholangitis = RUQ pain, jaundice, fever, AMS, hypotension (Reynold’s pentad or Charcot’s triad), markedly elevated ALP
Acute hepatitis = history of alcohol use, AST:ALT is 2:1, tender hepatomegaly!!!
Painful versus painless vision loss
PAINFUL = optic neuritis, GCA, acute angle closure glaucoma
PAINLESS = central retinal artery or vein occlusion, retinal detachment
Patellar dislocation treatment
Closed reduction + follow up XR to r/o fractures, then knee immobilization and rest with orthopedic follow up
Respiratory distress treatment algorithm
Start with nasal cannula 6 L –> venturi mask –> nonrebreather –> high flow nasal cannula –> noninvasvie positive pressure ventilation –> endotracheal intubation
What meds provide mortality benefit in ACS?
BASH + DAPT + anticoagulants + beta blockers + statins
Treatment of stroke 2/2 sickle cell in kids
Exchange transfusion (tPA not indicated in kids)
Is bowel/bladder retention or incontinence more specific for cauda equina?
Retention – incontinence only develops later in disease as a result of overflow
Which is more sensitive for cauda equina – bowel/bladder retention or saddle anesthesia?
Bowel/bladder retention
ADRs of ace inhibitors
Cough
Hyperuricemia/hyperkalemia
Angioedema
Dose 1 hypotension
ADR of amiodarone
Pulmonary toxicity with chronic use – lead to pulmonary fibrosis
ADR of heparin
Thombocytopenia leading to bleeding and microthrombi formation (tx of HIT = d/c heparin, start a direct thrombin inhibitor i.e. dabigatraban)
ADR of metoprolol
Hypotension, erectile dysfunction, lightheadedness
ADRs of tPA
Hemorrhage/bleeding, anaphylaxis/allergic reaction/angioedema
Top 2 diagnoses for flank pain
Nephrolithiasis
AAA –> get a CT AP with contrast!
Which is more reliable for ruling out testicular torsion: presence of Prehn or cremasteric reflex?
Presence of cremasteric reflex
What structure is most commonly injured in ski accidents?
Ulnar collateral ligament d/t forced radial abduction
Skier thumb presentation and treatment
TTP on ulnar side of MCP joint, weak pincer grasp
Thumb spica splint, ortho referral
MC location of mesenteric ischemia
Superior mesenteric artery (d/t emboli, uncoagulated afib = high risk), jejunum most affected
Myocarditis diagnostic tool gold standard
Myocardial biopsy (though rarely performed, often a clinical diagnosis – echo can show hypokinesis and decreased ventricular ejection fraction)
Protein and LDH ratios in transudative vs exudative pleural effusion
Transudative = low protein ( < 0.5) , low LDH ( < 0.6) with respect to the pleural fluid
Exudative = high protein ( > 0.5), high LDH ( > 0.6) with respect to the pleural fluid
*** ratio is pleural serum:fluid
What kind of events are most likely to cause PTSD?
Sexual trauma
Treatment for asymptomatic first degree AV block
Reassurance, no intervention necessary
When should you start with ordering a D dimer for suspected DVT?
If suspicion is low/moderate after doing Wells and you are unable to PERC them out, b/c a negative D dimer will r/o DVT without any imaging
What tests are required to make a diagnosis of pyelonephritis?
Only a UA, (+) for WBCs, leuks, nitrates if E. coli is causative organism (non con CT AP would help look for potential obstruction but not inflammation associated with pyelo)
What are drusen spots associated with?
Macular degeneration
Classic physical exam finding a/w PCP toxicity + treatment?
Rotary nystagmus (like a diagonal nystagmus) + feeling of superhuman strength, combative
Treatment = benzodiazepines
1st line gout treatment in pts with kidney disease
Prednisone (colchicine and NSAIDs CI in CKD)
Hematuria work up
MCC of hematuria: UTI, trauma, stone
Initial workup: UA, full H&P, assess kidney function with Cr
If initial workup does not yield cause: renal US or CT AP w/ contrast to look for structural disease or mass (now have concern for malignancy)
Renal ADR of chronic lithium toxicity
Nephrogenic DI d/t arginine vasopressin resistance
Interstitial nephritis
Kidney failure
What is the specific finding on echo for cardiac tamponade?
Diastolic collapse of RV
Risk factors for depression mnemonic
SADPERSONS
Sex (MC in M than F)
Age (increased risk in M > 45 y/o) and adolescents)
Depression
Previous attempt
Ethanol or drug use
Rational thinking loss
Social supports lacking
Organized plan
No spouse
Sickness (mental health disorder or general medical issue)
What are the 8 PERC criteria?
Age greater than or equal to 50
History of PE or DVT
Recent surgery or trauma
Taking oral contraceptives
Unilateral leg swelling
HR greater than or equal to 100
O2 sat < 95% on RA
Hemoptysis
Pharmacologic treatment of Meniere’s
Thiazide diuretics (and salt restriction)
What is a felon and what is the best treatment?
Felon = pyogenic infection of digital subQ tissue usually d/t staph aureus (gram positive cocci in clusters)
Tx = I&D + antibiotics if overlying cellulitis present
Which form of vaginitis has a pH < 4.5?
Candidiasis
Ottawa ankle rules
Get an ankle XR if:
- Unable to bear weight for more than 4 steps
- Bony tenderness at medial or lateral malleolus
- Bony tenderness in mid foot
Get a foot XR if:
Pain in midfoot PLUS…
- Navicular tenderness
- Pain at base of fifth metatarsal
- Unable to bear weight
Saturday night palsy nerve involvement + presentation
Radial nerve damage
S/sx: weakness of brachioradialis, wrist drop (manifestation of weak wrist extensors), weakness of finger extensors
Distinguishing tension pneumo and pericardial effusion/tamponade on physical exam
Tamponade: JVD, hypotension, decreased CARDIAC sounds on auscultation (bilateral), breath sounds usually present
Tension pneumo: JVD, hypotension, decreased BREATH sounds on auscultation (unilateral to side of injury)
Where do you perform decompression in a pneumothorax?
2nd ICS in midclavicular line OR 4th/5th ICS in anterior axillary line
Treatment of stable vs unstable sinus bradycardia
Stable = observation
Unstable = start with atropine, consider epi/norepi if unresponsive, consider transcutaneous pacing
TTP manifestations and best treatment
FATRN: fever, anemia (likely d/t hemolysis), thrombocytopenia, renal dysfunction, neurologic deficits/dysfunction
Treatment: plasmapharesis to address both anemia and TCP (avoid platelet transfusion if possible bc additional platelets will be destroyed given microvascular circulation)
PDA treatment
Indomethacin within first 10-14 days of life
Umbilical prolapse presentation and treatment
Fetal heart decels, pulsating mass protruding from cervical os
Tx: immediate/emergent C section, elevate presenting part (maternal knee to chest positioning, Trendelenburg) in time prior to delivery
MC valve involved in endocarditis leading to embolic events?
Tricuspid (mitral regularly)
Treatment of choice for lice?
Permethrin (ok in pregnant, lactating women, kids)
Strangulated hernia presentation and treatment
Mass near or in scrotum, toxic appearing, s/sx of SBO (N/V – bilious, abdominal pain, hyperactive BS early on to absent BS later on)
Alcohol related hepatitis tx
Supportive care
Which bursa does the knee joint communicate with?
Suprapatellar – this is why you can “milk” knee joint effusions
What finding indicates pneumothorax on CXR?
Ability to see pleural edge indicating buildup of air in pleural space
What is Nikolsky sign?
Sliding of epidermis away from underlying dermis
Which has a negative Nikolsky sign, bullous pemphigoid or pemphigus vulgaris?
Bullous pemphigoid (THINK: this is BULL, NO way I have a Nikolsky sign)
How can you tell if acidosis/alkalosis is acute vs acute on chronic?
Acute = no signs of compensation
Acute on chronic = signs of compensation (i.e. ROME is present but the other respiratory/metabolic process is also abnormal in an effort to compensate)
Which of the MOAN meds in MOAN and BASH for ACS has a proven mortality benefit?
Aspirin
What are the 2 instances where you DONT do a CT AP with contrast?
If pt has CKD, if solely looking for nephrolithiasis