EOR Flashcards
when does surfactant production surge?
after 36 weeks (steadily increases 33-36 weeks)
When is surfactant produced?
20 weeks
what is found on CXR in NRDS?
ground glass appearance w/ bronchograms
what endocrinopathy is associated w/ SCFE?
hypothyroidism
does mono cause posterior or anterior cervical lymphadenopathy?
posterior cervical lymphadenopathy
What risks are associated with gestational DM?
hypoglycemia, shoulder dystocia, HCOM, NRDS, congenital anomalies, PCV, jaundice, electrolyte disturbance (hypomag, hypocalcemia), caudal regression syndrome
macrolide use in newborns can cause what complication?
pyloric stenosis
which meds exacerbate hypercalcemia?
thiazide diuretics & lithium
ADEs of thiazide Diuretics?
hyponatremia
hypokalemia
hypomagnesemia
HYPERcalcemia
treatment of non-blistering, non-systemic, confined poison ivy rash?
clobetasol propionate 0.05% x 14 days (need longer corse bc it is a delayed Hypersensitivity rxn)
which heavy metal deficiency is associated with telogen effluvium?
zinc
Kawasaki Disease Symptoms
[CRASH and Burn]
Conjunctivitis
Rash
Adenopathy
Strawberry tongue
Hand or foot edema
Uncontrolled high fever (burn)
preferred monitoring for neonates who delivered breech d/t risk of DDH
US @4-6 weeks
what is normal BS during first day of life?
> 45 mg/dL
erythema toxicum neonatum
common, non-threatening rash that affects newborns. It usually appears within the first week of life, but can appear as early as the first few hours, and affects 4–70% of newborns
most common risk factor for developing pulmonary non-tuberculous mycobacterial disease in children?
CF
murmur of coarctation of the aorta
SYSTOLIC EJECTION MURMUR best heard at LUSB w/ radiation to the L inter-scapular area
otitis media & conjunctivitis (otitis-conjunctivitis syndrome) is a sign of what infection & requires which abx?
non-typeable HIB
tx w/ amoxi-clav
what is the most useful lab test to assess degree of dehydration in children?
serum bicarb
at what age is bronchiolitis less likely cause of pulmonary symptoms?
6+ years old
4-2-1 rule for hourly pediatric maintenance fluids
<10 kg: 4 ml/kg/hr
10-20kg: 40 ml + 2 ml/kg for every kg > 10 kg
> 20 kg : 60 + 1 ml/kg for every kg > 20 kg
pneumonia vs bronchiolitis on auscultation
bronchiolitis has diffuse crackles & wheezing
pneumonia has more focal findings
treatment for status asthmaticus?
SABA + Steroids
substances to kill live insect in the ear canal
mineral oil, lidocaine 1%, ethanol 95%
where is atopic dermatitis located on YOUNG kids?
EXTENSOR SURFACES
** diff than adults & older kids which is usually on flexoral surfaces
Irritant Diaper Rash spares what?
genitocrucal folds
Candidal rash involve or spare genitocrural folds?
involves genitocrural folds & is commonly isolated to the perineal area
Burns in Children
anterior head: 9%
posterior head: 9%
anterior torso: 18%
posterior torso: 18%
anterior leg, each 6.75%
posterior leg, each 6.75%
anterior arm, each 4.5%
posterior arm, each 4.5%
genitalia/perineum 1%
common cause of erythema multiforme in children
mycoplasma pneumoniae
is nikolsky sign +/- in erythema multiforme ?
NEGATIVE
6 Ps of Lichen Planus
purple, polygonal, planar, pruritic, papules or plaques
(autoimmune disease)
will also see wickham strae = fine white lines on the surface of the lesions
tx = corticosteroids
SJS/TEN where does it start & spread?
starts w/ acute onset on face/upper trunk, palms/soles and spreads distally & to extremities
superficial partial vs deep partial 2nd degree burns
superficial partial is painful to temp, air, touch
deep partial is painful to deep pressure only.
both blister & blanch with pressure
which degree burn does NOT blanch w/ pressure?
3rd degree
what is CI in initial care of a burn?
ice or ice water - can cause pain & increase depth of the burn
drugs causing erythema multiforme
sulfa
oral hypoglycemics
anticonvulsants
Penicillin
NSAIDs
(SOAPS)
MCC is HSV or mycoplasma infx (think post URI in kids)
isotretinoin monitoring/screening
SE:
- hyperlipidemia
- hepatotoxicity
- depression
- inflammatory bowel disease
- ankylosing hyperostosis
- teratogenic
Screening (initiation)
- Depression screening
- baseline liver panels
- lipid panels
- pregnancy test
- confirm x2 BC measures
MC type of psoriasis in children
plaque
[guttate is common in children but not MC]
tx for non-systemic poison ivy
topical triamcinalone x 2-3 weeks
first line tx verrucae
salycylic acid or cryotherapy
do HPV vaccines target strains that cause verrucae (common wart)?
NO
rash on newborn babies that appears like acne in first 2-7 days of life?
erythema toxicum neonatorum
Which neonatal dermatologic condition occurring around 3 weeks after birth and caused by a reaction to Malassezia species is characterized by inflammatory pustules on the cheeks without the presence of comedones?
Neonatal cephalic pustulosis
teratogenic in the first trimester by increasing risk of congenital cataracts, SNHL & heart Disease
Rubella
TX OF SEB DERM IN INFANTS
MINERAL OIL
hx of tet spells (cyanosis w/ crying/feeding/pooping) and squatting for relief
tetraology of fallot
tetraology of fallot four components
PROVe
PDA
RVH
Overriding Aorta
VSD
recommended supplementation for breast-feeding infants?
vitamin D
400 IUD
what is tx for otitis media?
HIGH DOSE amoxicillin
80-90 mg/kg/day in divided doses BID x 10 days
** need high dose to exceed MIC of s. pneumonae & target non-susceptible strains
calcium needs by age
0-6 mo: 210 mg
6-12 mo: 270 mg
1-3 yrs: 500 mg
4-8 yrs: 800 mg
9-18 yrs: 1300 mg
when should you start introducing solid foods
4 months
when can babies start drinking water?
6 months
when should a babies weight double from birth weight?
4 months
when should routine POCT lead testing performed?
12-24 months
[CDC recommends 12 months as this is when children are walking by holding on to furniture & pulling to stand]
spot hemoglobin screening in babies for anemia is indicated when?
9-12 months
age indications for RSV vaccination
up until 19 months then child ages out
exclusive breastfeeding vitamin supplemention?
4000 IUD vit D
causative agent of impetigo?
S. Aureus
(GAS ~10%)
Treatment of Disseminated impetigo?
cephalexin (keflex)
exanthem of rubella (german measles)
pink/red non confluent maculopapular rash that starts on face & spreads to trunk & extremities x 3 days
Spreads more rapid than measles (rubeola) & is much darker & more confluent
rubeola (measles) sx
3 Cs [cough, coryza, conjunctivitis] + rash
only viral exanthem that begins on the trunk
roseola
which exanthem can be treated with vitamin A
measles (rubeola)
pertusis tx
azithromycin
TOC If genital lesions are absent or if the lesions are crusted over and no vesicular fluid can be obtained?
serologic testing for HSV antibodies
prevention of Congenital CMV
high-dose oral valacyclovir administered prior to 14 weeks gestation and within 8 weeks of the maternal infection ↓ vertical transmission
s/sx congenital CMV
chorioretinitis, periventricular calcifications, SNHL, hepatosplenomegaly, thrombocytopenia rash (petechiae), IUGR
congenital toxoplasmosis
diffuse calcifications/periventricular calcifications, hydrocephalus & chorioretinitis
varicella vaccination schedule
dose 1: 12-15 mo
dose 2: 4-6 yrs
PE will show prominent lymphadenopathy (occipital, cervical, postauricular) and a rash that spreads from face down
Rubella
premature birth occurs when?
born before 37 weeks
Orajel CI in children under 2
can cause methemoglobinemia 2/2 to benzocaine in thew product - amt of oxygen carried by RBCs is reduced which can lead to death
obesity definition
BMI of 30 kg/m^2 or greater OR body weight 20% over the ideal weight
**Children are considered to have obesity when the body mass index (BMI) is > 95th percentile for age and sex.
somogyi effect
Nocturnal hypoglycemia followed by rebound hyperglycemia
[sooo much insulin]
dawn phenomenon
Normal glucose until rise in serum glucose between 2-8 am
tx of DKA
[SIPS]
Saline, Insulin (regular), Potassium repletion, Search for underlying cause
determining DKA severity
bicarb levels more important than glucose
levels in determining severity of DKA
common cause of HHS
profound dehydration
true or false: HHS is not usually associated with severe ketosis or acidosis?
true
s/sx of congenital hypothyroidism
- large fontanelles
- hypotonia
- hypothermia
- macroglossia
- hoarse cry
- umbilical hernias
genetic disorder assoc. w/ hypothyroidism
Trisomy 21
What percentile translates to a definition of short stature?
23rd percentile
BMI between 5-85th percentile
healthy weight
BMI between 85-95th percentile
overweight
BMI > 120% of the 95th percentile or > 35 kg/m2
severe class II obesity
painLESS rectal bleeding in a pt < 5 y/o
Meckel Diverticulum
indications for sending to ED in depression
- have a plan for suicide
- expressing imminent intent to hurt one’s self
- having access to the planned means to attempt suicide
- the inability to contract for safety
murmur of VSD
2/6 mid-frequency holosystolic murmur heard best at the fourth left intercostal space, a diastolic rumble, and a prominent apical impulse displaced laterally
egg allergy is a precaution for which vaccine?
influenza
plaque
elevated area of skin 2 cm or more
(can be considered a wheal and/or present in urticaria)
when to treat a cutaneous wart in children?
when it is painful or discomfort is experienced
[watchful waiting is rec. as many resolve spontaneously w/n 2 years]
when are two doses of influenza vaccine are recommended?
children 6 mo - 8 years old
s/sx of fetal alcohol syndrome
- short palpebral fissures
- a short nose
- a thin upper lip with a smooth philtrum
tx for hereditary spherocytosis?
splenectomy
why limit milk to 16 oz / day in newborn children?
risk of iron deficiency anemia
adherent white plaques on tongue, palate & inner cheeks that CAN be scraped off (may cause bleeding)
oral thrush (candida albicans)
treatment of croup?
nebulized racemic epinephrine
Tropia vs Phoria
tropia = strabismus
phoria = latent strabismus which is only evident w/ one eye is covered
how long can babies have strabismus?
up to 12 months
most appropriate dx test for Acute Rheumatic Fever?
echo
ectopic testes vs. undescended testes
undescended: once massaged into the scrotal sac, will remain there as cremasteric muscle relaxes
ectopic: will immediately spring back out of the scrotum
RF for pyloric stenosis?
1st born male
** also erythromycin use
hypochloremic, hypokalemic metabolic alkalosis
pyloric stenosis
reflux in newborn vs. milk protein allergy?
reflux = spitting up after feeds, better with raising the head, will resolve as LES tightens ~3-4 months
mil protein allergy= spitting up, fussy after feeds, loosing weight, blood in stool, possible dermatitis
barking cough + inspiratory stridor
croup
[parainfluenza virus; tx w/ dexamethasone & racemic epinephrine]
1 tx for allergic rhinitis
intranasal glucocorticoids
MOA: act on nasopharynx directly to reduce mucosal inflammation
ex. fluticasone, beclomethasone, mometasone
pathophysiology of hypertrophic cardiomyopathy
mutations in the genes for sarcomeric proteins
1st line tx of otitis media w/ perforation
PO amoxicillin x 10 days
s/sx of bronchiolitis
diffuse crackles & scattered expiratory wheezes w/ subcostal retractions & nasal flaring
characteristics of herald patch of pityriasis rosea
large salmon-covered herald patch that gradually regresses
as lesion resolves: center clears & margins develop scale
neonate presenting with fever should always consider what on ddx?
congenital HSV infection
[dx with PCR of cerebrospinal fluid]
Vit D deficiency causes which disorder?
Rickets
ASD murmur
Mid-systolic pulmonary flow or ejection murmur w/ fixed split second heart sound
topical acne tx that is CI in pregnancy
- Tazarotene (retin A) [category x]
- Clindamycin
- Azelaic acid
- BPO
rule of 2’s is for what dx?
Meckel Diverticulum
2 year old
2 feet from ileocecal valve
2 inches long
2% population
2 epithelial types (gastric, pancreatic)
polyehylene glycol is what medication?
miralax (stool softner)
gold standard in dx of children w/ lead poisoning
venous blood lead level
acyclovir indications for varicella tx?
- unvax adults & child 12+ y/o
- pregnant
- immunocompromised
blood lead level requiring chelation therapy
> /= 45 mcg/dL
four H’s of Scurvy [vit C aka ascorbic acid deficiency]
- hemmorhage (petechiae, gingival bleeding)
- hyperkeratosis (rough skin, loose teeth)
- hypochondriasis( emotional changes)
- hematologic abnormalities (easy bruising)
only d/o that causes increased MCHC?
hereditary spherocytosis
2 cell lines down on cbc + abnormal sx (bone pain, unspecified limp, bruising) … you should think?
Non-Solid Malignancy (Leukemia, Lymphoma)
tx Kawasaki disease?
IVIG+Aspirin
mcc of anemia btwn 6-9 weeks
physiologic = 2/2 decreased erythropoiesis d/t increased tissue oxygenation
btwn 6-9 wks hg goes from 14 –> 11 g/dL
blanching rash that starts in the groin & axillae, spreads to trunk/extremities & spares palms/soles
Scarlett Fever
retropharyngeal abscess vs peritonsillar abscess?
Retropharyngeal Abscess: forms between prevertebral fascia & constrictor muscles –> sx include fever, sore throat, NUCHAL RIGIDITY, muffled voice, stridor
Peritonsillar Abscess: sx include unilateral tonsillar swelling, fever, hot potato voice w/ uvular deviation
fever, hypotension, desquamation & mucosal hyperemia?
TSS complication of nasal packing
protective factor in otitis media
breastfeeding
tx of acute tympanic rupture?
PO Amoxicillin or amoxi-clav if otitis-conjunctivitis syndrome
risk associated w/ PO erythromycin for pt < 2 weeks old
development of pyloric stenosis
tx of uncomplicated mastoiditis
IV abx & myringotomy (middle ear drainage)
tachypnea in the newborn
> 70 RR
croup vs. bacterial tracheitis
croups is non-toxic appearing w/ barking cough
bacterial trachiectasis has barking cough + toxic appearing
MCC of bacterial tracheitis
staph aureus
CAP tx based on age
< 6 mo old = inpatient
mild & > 6 mo old = amoxicillin
> 5 y/o = consider azithro or doxy to cover for mycoplasma or chlamydia pneumonae
what sweat chloride value indicates CF?
> /= 60 mEq
common asthma trigger in warm environments
dust mites
*educate pt on washing sheets & blankets weekly in hot water
meds that exacerbate asthma sx
NSAIDs
ASA
non-selective BB
ACEi
medication that decreases hospitalizations in pt born prematurely
palivizumab
** monoclonal antibody against RSV glycoprotein
best test for bronchiectasis
CT scan of the lungs
common finding in CF HEENT exam?
nasal polyps
MCC of bacterial tracheitis
staph aureus
what medication is increased in the step up approach to Asthma?
increasing the strength of the steroid in the ICS-LABA medication
what is a Cardiorespiratory monitor?
mini EKG (not full 5 lead) & RR (but not super accurate)
does NOT give you pulse ox
asthma vs reactive airway disease?
typically 2-3 y/o is cut off for pursuing diagnosis of asthma
** tx is relatively the same
URI vs bronchiolitis?
in bronchiolitis respiratory exam will improve/exam will change with secretions and coughing
URI: less symptoms in the chest
how many calories = 1 lb
500
pt with anorexia who is acidotic on acid-base analysis?
most likely abusing laxatives and pooping bicarb
when is MCHAT screening performed?
16-30 months
In infants is severity of retinal hemorrhages assoc. with liklihood of abuse?
yes
when is D5NS not indicated for pediatric maintenance fluids?
children presenting in the ED w/ history of eating disorder
** will push kid into refeeding syndrome 2/2 to insulin surge which decreases lites (K, phos, mag)
in patients < 25 what warning should be given before initiating SSRIs?
black box warning for increased risk of suicide ideation & behavior
increased LDH
increased homocysteine
INCREASED methylmalonic acid
Neuro Symptoms
B12 deficiency (pernicious anemia)
no neuro symptoms
Increased homocysteine
NORMAL methylmalonic acid
folate deficiency
what happens to haptoglobin levels in hemolytic anemia?
DECREASED
** binds all the free Hgb released from the RBC destruction
EPISODIC hemolytic anemia assoc. W sulfa drugs, fava beans, infections
G6PD
(-) coombs tests, (+) bite cells & heinz bodies
coombs positive
think: MAHA
Only anemia where all three cell lines are decreased (WBC, RBC, PLT) - pancytopenia
aplastic anemia
** ddx should include non-solid malignancies
causes of prolonged PTT
Intrinsic pathway
Heparin, DIC, vWD, Hemophilia A&B, antiphospholipid syndrome
causes of prolonged PT
Warfarin therapy, vitamin K defiency, DIC
hemophilia A
factor 8 Deficinecy
hemophilia B
factor IX deficiency
[Christmas Disease]
patho of factor V leiden
Protein C stops fx of factor V to decrease clot formation; in this d/o there is a mutation in factor V so that it does not respond to inhibition from factor C = increase clotting
s/sx: DVT, PE, miscarriages etc.
** PT & PTT are normal bc not affected
HUSS
hemolysis
uremia (inc. BUN & Cr)
shitting (GI sx)
school aged
s/sx of protein C&S defiency in newborns
purpura fulminans in newborns - red purpuric lesions at pressure points, progresses to painful black eschars
delayed bleedng or swelling in weight-bearing joints (hemarthrosis) should make you think of what disorder?
hemophilia (A or B)
**will have prolonged PTT, normal PT
** PTT will correct with mixing studies
inheritance of VW disease
autosomal dominant
[MC inherited bleeding disorder]
anemia, thrombocytopenia w/ 20% blasts on bone marro aspiration
ALL
Child + LAD + bone pain + bleeding + fever +
>20% blasts
ALL
(+) smudge cells
CLL
middle age + asymptomatic + fatigue + LAD + splenomegaly
+ myeloblasts on bone marrow biopsy & (+) auer robs
AML
philadelphia chromosome (translocation of 9&22)
CML
** must be treated with a tyrosine kinase inhibitor (imatinib)
- painLESS lymphadenopathy or pain w/ alcohol ingestion
- mediastinal mass
- b symptoms
- (+) reed sternberg cells
hodgkin lymphoma
treatment considerations in pediatric patients with hodgkins lymphoma
Pretreatment: benzodiazepines to help w/ N/V
Postreatment: 5-HT3 can be helpful in first 24 hours following tx
type of NHL associated with EBV
Burkitt Lymphoma
anemia assoc. w/ carbamazepine
aplastic anemia
anemia assoc with parovirus B19 in sickle cell patients
aplastic anemia
tx for severe aplastic anemia
allogenic hematopoeitic stem cell transplant
bone marrow biopsy w/ increased myeloblasts but < 20%
myelodysplasia –> can progress to AML
myeloid cell lines
RBC
PLT
Granulocytes: eosinophils, basophils, neutrophils
lymphoid cell lines
B lymphs –> plasma cells
T lymphs
NK cells
AML vs CML
AML involves myeloblasts
CML invovles granulocytes (neutrophils)
ALL
anemic, lumpy (hepatosplenomegaly), limping
what is needed in treatment of ALL
prophylaxis the CNS w/ methotrexate
ALL can remain dormant in CNS and pt will present with relapse of leukemia w/ meningitis
APL
a form of AML
absolute lymphocytosis [WBC 5,000+ ]
CLL
fever of unknown origin ddx should include what 3 subcategories of dz?
infectious, malignant, rheumatologic
what happens to BP and venous return in asthma attacks?
wide pulse pressure (low diastolic) 2/2 to low venous return from increased ITP & expansion that impedes flow in the IVC
paraphimosis
EMERGENCY
retracted foreskin that can’t be returned to normal position
(think post foley catheter placement for surger)
phimosis
inability to retract foreskin over the glans
when is phimosis considered normal?
children < 5 y/o
(typically resolves by 5 y/o)
auricular hematoma
accumulation of blood in the subperichondrial space, usually secondary to blunt trauma
s/sx of auricular hematoma
edematous, fluctuant, & ecchymotic pinna with loss of normal cartilaginous landmakrs
etiology of auricular hematoma
spontaneous in babies, perichondritis, bleeding diathesis
MC. innocent murmur
pulmonary flow murmur
[2/2 small size of the branched pulmonary arteries d/t the lung receiving only
15% of CO during fetal development]
tx of acute cystitis
2nd or 3rd gen cephalosporin
cefuroxime, cefdinir
wilms tumor
firm, nontender abdominal mass that does NOT cross the midline
MC kidney malignancy in teens 15-19 y/o
RCC
HTN, hematuria & periorbital edema
nephritic syndrome
severity of accessory muscle use
subcostal –> intercostal –> tracheal tugging –> nasal flaring
Jaundice Progression
starts on face and spreads down
What happens to K+ with renal hypoperfusion?
HYPOkalemia
diagnosis criteria of constipation
2 of the following:
infrequent bowel movements (<2/week)
Straining
hard stools
feelings of incomplete evacuation
use of digital maneuvers
sensation of anorectal obstruction/blockage w/ 25% of BMs
Above must be fulfilled for last 3 months w/ symptoms onset 6 months prior to discharge
sx of dehydration in children
pee/pressure
anterior fontanelle
refill (cap)
crying
HR
skin elasticity
dryness (membranes)
sterile pyuria is a indication of what disease?
kawasaki dz
gold standard test for GERD
24 hour ambulatory pH monitoring
GERD sx < 2x/week
antacids, H2 antagonists
GERD sx > 2x/week
PPI
protrusion through the internal inguinal ring & possibly into the scrotum
indirect inguinal hernia
d/t patent process vaginalis
protrusion through the external inguinal ring
direct inguinal hernia
severe abdominal PAIN in pt with anorexia
Superior mesenteric artery (SMA) syndrome
[weight loss-induced atrophy of the mesenteric fat pad, causing compression of the third part of the duodenum -> small bowel obstruction]
vomiting + abdominal pain + bloody stool (currant jelly stool)
intussusception
pathologic jaundice
present in 1st day of life
physiologic jaundice
typically presents first 3-5 days of life and lasts ~ 1 week
Kernicterus
cerebral dysfunction and encephalopathy due to bilirubin deposition in brain tissue
s/sx= seizures,
lethargy, irritability, hearing loss, mental developmental delays
associated with bilirubin levels 20 mg/dL+
dubin-johnson syndrome
hereditary conjugated (direct) hyperbili
dubin + direct + dark liver
** typically presents in adolsecents
(+) dirct coombs test in baby
Rh incompatibility
ABO incompatibility
patho of crigler-najjar syndrome
absence of UGT enzyme = unable to conjugate bili = increased indirect bili = jaundice
** this often does not respond to phenobarbitl stimulation
Gilbert Syndrome
hereditary unconjugated hyperbili w/ transient episodes of jaundice during periods of stress, fasting, alcohol, illness
B3 deficiency
dermatitis (photosensitive), diarrhea, dementia
best test to confirm dx of lactose intolerance?
hydrogen breath test
test to r/o IBD?
fecal calprotectin
(+) serum tissue transglutimase antibody
celiac dz
tx of intussusception?
air or contrast enema
(pressure will straighten out the intestine)
abdominal distention & postive squirt sign
Hirschsprung Disease
string sign on UGI series?
pyloric stenosis
vomiting first day of life should make you think?
duodenal atresia
colic age group and tme duration
occurs in children < 3 mo
resolves typically by 9 weeks
otherwise healthy infant who is < 3 months of age who cries for ≥ 3 hours per day ≥ 3 days per week without a clear explanation,
colic
when and what are the first teeth to erupt?
central incisors @ 5-8 months
when should all teeth be in?
2.5 y/o
when do secondary teeth begin to grow?
6=7 y/o
what cardiovascualr d/o is assoc w/ turner syndrome?
coarctation of aorta (30%)
labs assoc with turner syndrome
Low Estrogen
high FSH & LH
rocker bottom feet are associated with which genetic d/o?
trisomy 18 (Edward syndrome)
short stature, webbing of the neck, low hairline, and widely spaced nipples, Sheild chest
Turner syndrome (45 XO)
which congenital heart defet is associated with down syndrome
VSD
simple febrile seizure
number of seizures: 1
duration: < 15 mins
type: generalized
complex febrile seizures
number of seizures: >1 in 24 hours
duration: >15 mins
type: focal or generalized
empiric abx coverage for meningitis in pt < 1 mo
cetoximin + amp OR gentamicin + amp
CI to ceftriaxone
hyperbili in infants
growth during growth spurt?
limbs grow before truck
MC benign primary brai tumor of childhood?
grade I astrocytoma
brain tumor sx by location
cerebellum: weakness, tremor, ataxia
visual pathway: visual loss nystagmus, proptosis
spinal cord: pain, weakness, gait disturbance
MC malignant brain tumor of childhood?
medulloblastoma
enterobius vermicularis
pin worm
- recurrent upper tract bacterial infections
- renal scarring
- hyperntension
vesicoureteral reflux complications
treatment of vesicouretral reflux
< 2 m = TMP-SMX, nitrofuratonin
> 2 m = cephalexin, ampicillin, amoxicillin
CXR finding in aspiration?
unilateral hyperinfaltion, mediastinal shift, atelectasis
black box warnings of gentamicin
neurotoxicity, ototoxicity, nephrotoxicity, neuromuscular blockade
atypical pneumonia
MCC is mycoplasma pneumoanie
typically less severe symptoms –> less toxic appearing (low grade, temp, URI sx)
1st line uncomplicated cystitis
cephalosporins (cefixime)
inital tx of encoporesis?
colonic dissimpaction & longterm oral laxative therapy
mcc of intestinal obstruction btw 6-36 mo of age?
intussusception
Ortolani Maneuver
abduction & elevation to feel for reducibilyt –> audible click/clunk
this can temporarily reduce the dislocation
barlow Maneuver
gentle adduction w/o downward presure to feel for dislocatability
how long is pt in hip spica splint for DDH
6-15 months
MC site of osteosarcoma
90% occur in **metaphysis of long bones **
distal femur > promimal tibia & proximal humerus
when do you start screening BP in kids?
3 y/o
Osteogensis Imperfecta
autosomal dominant d/o 2/2 to mutations in collagen
multiple fx, HL, blue sclera, increased laxity of joints
** can treat with bisphosphonates or surgery
joint pain or antalgic gait in child who was recently sick
transient synovitis
Tx threshold for ASD
> 3-5 mm requires frequent f/u
symptomatic mgmt = diuretics, ACEi, digoxin
surgery = 1 cm + symptoms
Continuous machine-like murmur loudest @ pulmonic area (LUSB - 2nd intercostal space)
PDA
coarctation of the aorta
SYSTOLIC EJECTION MURMUR best heard at LUSB w/ radiation to the L interscapular area
Late systolic ejection murmur/continuous murmur radiating to the left back, left
scapula or chest, heard in the aortic area
coarctation of the aorta
gold standard test for coarctation of aorta
angiography
young child w/ HTN
r/o coarctation of the aorta
Harsh systolic murmur @ left mid to upper sternal border
Tetralogy of Fallot
boot shaped heart
Tetralogy of Fallot
annual screening needed in pt with Tetralogy of Fallot
QRS width
two congenital HD that require PGE prophylaxis
Coarctation of aorta & tetralogy of fallot
Medium pitched harsh mid-systolic crescendo-decrescendo murmur heard @ LSB
murmur of HCOM
does valsava/standing increase or decrease murmur of HCOM
decreased venous return
Increase
does squatting, supine or leg raise increase/decrease HCOM murmur?
decrease
increase venous return
murmur w/ a loud S4 gallop and apical lift
HCOM
1st line tx of HCOM
beta blockers
HCOM precuations
AVOID dehydration, extreme exertion, exercise
Caution w/ digoxin, nitrates, diuretics
(Digoxin ↑ contractility, nitrates & diuretics ↓ LV volume)
MC congenital HD
VSD
High-pitched harsh holosystolic murmur best heard @ LLSB w/ palpable thrill
thrill increased in small abnormality
VSD
when should a VSD close by?
12 months
MCC of pediatric syncope
vasovagal or idiopathic
syncope Red Flags
syncope during exercise
multiple recurrence w/n short time
older age
heart murmur
injury during syncope
Fhx of sudden unexpected death
does direct or indirect bili cross the bbb
indirect –> leading to kernicterus
HR in infants ages 0-3 mo
100-204 bpm (when awake)
when do peds HR reach adult values of 60-100
8 y/o
fifth percentile of BP
70 mmhg + 2x age in years
diastolic murmurs
MS.PRARTs Died
MR vs. MVP murmur
MR = pansystolic
MVP = mid systolic click
radiographic finding in tetralogy of fallot?
Boot shaped heart
radiographic findings in coarctation of aorta?
aortic 3 sign & posterior rib notching
tx of coarctation of the aorta?
balloon angioplasty or open surgical repair
aortic diseases that cause BP to be lower in LE than UE
coarctation of aorta
Aortic dissection
supravalvular aortic stenosis
coarctation assoc with ANTERIOR or POSTERIOR rib notching?
posterior
not anterior bc intercostal arteries do not run along grooves in the ate
when should a PDA close?
before 3 days of life –> if extends beyond 3 days of life, is considered pathological
murmur + respiratory distress, bounding pulses, wide pulse pressure, abdominal distention, and prominent left ventricular impulse.
PDA
(machine like murmur)
Tx of a PDA
indomethacin
holosystolic murmur loudest at the apex (2/2 to MR) + S3 or S4
HCOM
digoxin MOA
positive inotrope which makes LV pump harder
worsens sx of HCOM
isosorbide dinitrate
vasoldilator –> decrease peripheral resistance
increased LV outle obstruction in HCOM
unilateral cervical lymphadenopathy
kawasaki disease
cyanosis worse w/ crying & feeding
Tetraology of Fallot
A harsh, medium- to high-pitched pansystolic murmur is heard best at the left sternal border in the third and fourth intercostal spaces with radiation over the entire precordium.
VSD
frequent respiratory infections and slow weight gain in addition to dyspnea, diaphoresis, and fatigue as early as 1–6 months of age.
VSD
Sequelae of VSD
irreversible pulmonary HTN
valsalva affect on venous return
decreased = decreased preload = increased murmur of HCOM
cervical venous hum
innocent murmur during > 1 y/o
continuous murmur heard best over L or R USB, infraclavicular area or supraclavicular area
accentuated w/ head extension while seated
lessens with supine position
most serious complication of kawasaki dz
coronary artery abnormalities
rare complication of KD?
macrophage activation syndrome
consequence of ASD
right atrial hypertrophy
maneuvers that increased VSD?
handgrip, squatting
2/2 to increased PVR
Amyl Nitrate
decreases afterload
characteristics of innocent murmurs
vibratory or musical
grade 2 intensity
short systolic duration (not holosystolic of diastolic)
crescendo-decrescendo w/o radiation
standing decreases intensity
inutero infx associated with PDA
rubella
rash of kawasaki dz
polymorphous rash
MC pathogen of infective endocarditis
Staph Aureus
MCC of pediatric aortic stenosis
bicuspid aortic valve
murmur of VSD
harsh holosystolic murmur is auscultated at the mid-left sternal border, and a thrill is palpated at the third left intercostal space
OCP recommended for PMDD
Drospirenone
progesterone-only OCP
first line tx for complex partial seizures
(focal onset impaired awareness seizure)
levetiracetam
common tx in generalized seizures
lamotrigiene & valproic acid
rash that starts behind the ears (on face) & spreads to trunk
commonly appears 2-4 days after fever & spares palms/soles
measles (rubeola)
definitive dx of measles
anti-measles IgM
detected 3 days after onset of rash
anti-measles IgM detected until 14 days after rash appears
otitis media w/ effusion presentation
retracted tympanic membrane w/ DECREASED motility on insufflation
can you use topical therapy in tinea capitus
no –> inadequate penetration
tx w/ oral antifungals [terbinafine, griseofluvin x6-8 weeks]
griseofluvin = 1st line
ADE of repeated oxymetazoline use
rhinitis medicamentosa
tx of anterior vs posterior epistaxis
anterior: pressure, Afrin, silver nitrate cuatery
posterior: packing & consult ENT
s/sx primary congenital hypothyroidism
slow growth, hypotonia, umbilical hernia, macroglossia, large fontanelle, dry skin, hypothermia, jaundice, intellectual disability
** not usually present at birth
dx of congenital hypothyroidism
heel sticxk measurement of free T4 & TSH in every newborn
emergent mgmt of epiglottitis
bag mask ventillation
after emergent mgmt –> humidified oxygen + ceftriaxone/vancomycin
thumb print sign on lateral xray
epiglottitis
simple febrile seizure tx
acetominophen
HL screening in children of average risk
4,5,6,8 and 10 years
inc. risk –> 24 & 30 months (e.g. those with NICU stay, ototoxic drug exposure - gent)
tx of severe otitis externa w/ edema & occlusion
wick placement & topical otic solution w/ abx + glucocorticoids
RF necrotizing otitis externa
DM, immunocompromised
common skeletal abnormality seen in Marfan Syndrome
scoliosis
** also assoc. with AA & dissection
RF for cleft palate
cigarette smoking
Alchol consumption
Folate deficiency
** majority cleft palates are unilateral
gingivostomatitis
HSV1 infx w/ prodrome of fever, irritability, HA or tingling/burning sensation
presents with ulcerations of gingiva or mucous membranes –> perioral vesicular lesions
Herpangia
etiology: coxsackie virus
painful, posterior pharyngeal lesions that DO NOT bleed
eryhtematous-based macules –> papules –> vesicules –> central ulcers w/ erythemous halo
LT mgmt of SVT
radiofreuqency catheter ablation
typical presentation of osteosarcoma
pain + soft tissue mass
weakest part of pediatric bone
diaphysis (growth plate)
most effects med for MDD in children & adolescences
fluoxetine
also an SSRI w/ longer half-life, best for when kids miss doses
when does kawasaki dz require labratory testing?
incomplete KD –> pt w/ fever of unknown origin & absence of 4+ classic findings
- leukocytosis (neut dominant)
- anemia
- ESR/CRP elevation
- liver transaminases
- thrombocytosis
- sterile pyuria
pediculosis capitus tx
presents with scalp purityus & excoriations in multiple fam members
topical permethrin
how does eye move in a cover-uncover test w/ strabismus
will move in direction opposite of which it is deviated (corrects itself)
ex. eye that moves outward to fixate demonstrates esotropia)
at what age is new onset esotropia suspicious for CNS disease?
> 5 y/o
worsening cyanosis w/ poor feeding & tachypnea is sx of what d/o?
PDA
common trigger for constipation in young children?
change in diet e.g. introduction of cows milk
initial therapy for enuresis
education & motivational therapies
primary nocturnal enuresis
occurs after age 5 w/o ever achieving bladder control
2/2 is when pt has achieved bladder control and now has enuresis after age 5
MCC of CHL in children
otitis media
sits w/o assistance
9 months
pulls to stand w/o assistance
12 months
narrowed angle between the SMA & aorta –> duodenal compression
SMA syndrome in anorexia nervosa
occurs 2/2 to loss of mesenteric fat
dx with abdominal Xray or upper GI series
flue vaccine schedule in young children
6 months–> requires 2 doses 1 month apart
CI to rotavirus vaccine
hx of intussusception
T/F psychosis can manifest in some children w/ MDD as delusions or hallucinations?
True
protective factors against RSV
prenatal vit D supplementation & breastfeeding
when should you suspect vesicoureteral reflux?
recurrent UTIS
Indications for voiding cytourethrogram?
children not toilet trained, recurrent utis, abnl kidney US, s/sx of CKD
OR
**
fever > 102.2 & known urinary pathogen other than E.Coli**
abx prophylaxis w/ TMP-SMX or nitrofuratonin
med assoc with oral candidiasis
inhaled glucocorticoids
tx: nystatin suspension 100,000 units to each cheeck 4x/day
PE finding assoc with neonatal ARDS
expiratory grunting
Ages & Stages Questionarrie
reference for gross motor, fine motor, communication, problem-solving & personal socail domains
administered by 9,18, 30 months of age
diet recommendations for CF
high fat
high energy
fat soluable vitamins (ADEK)
(+) fitzpatrick sign
dermatofibroma
dimpling of skin w/ lateral pressure
elevated anti-thyroglobulin
hashimoto thyroiditis
diaper dermatitis tx
zinc oxide & nystatin
type of psoriasis common after strep infx
guttate psoriasis
tx of pityriasis rosea
reassurance
assoc. hx of atopy + dry/scaling skin on extensor surfaces
ichthyosis vlugaris
described kinda like lichen planus, 1st line tx is moisturizer
sx of complete airway obstruction
inability to speak
which reflex persists through life?
parachute
TOC for suspected partial KD (mucocutaneous lymph node syndrome)
echo
“DK no A”
pt is presenting in DKA w/o meeting w/o ph of 7.3 or HCO3 < 16
does throwing up make you more acidotic in DKA?
yes
this is why kids on insulin drips for DKA should be NPO
is Type 1 or 2 more aggressive in pediatric patients?
type 2 is more aggressive in pediatric pt
tx of measles pneumonia
Ribavirin
petechiae on soft palate (forscheimer’s spots)
Rubella
congenital rubella syndrome
fetal death
delivery
congenital defects
complications of congenital HSV
2/2 bacterial infx, pneumonia, encephalitis, reyes syndrome
difference btw KD and SF tongue findings
KD = red strawberry tngue
SF = white strawberry tongue
Punctate erythema beginning on trunk
spreading to extremities, becoming confluent
“sandpaper” feel to the rash.
flushed face with perioral pallor
rash fading in 4 - 5 days and followed by desquamation
scarlett fever
questionnaire offered at 6 months
ages & stages
2 month milestones
- turns head 180
- traks objects
- vocalizes in play (coo)
- smiles, knows parents
4 mo milestones
- clutches rattle/rolls
- hands together
- laughs
- enjoys looking around
6 month milestones
- sits up
- raking grasp
- vocal imitates
- responds to name
9- 11 months
- stands/cruises
- sits w/o support
- pincer grasp
- understands” no”
- feeds self
- waves
12-14 months
- walks with one hand
- builds two blocks
- uses one word with meaning
- hugs stuffed animals
15-17 months
- stoops & recovers
- builds 2-3 blocks
- 4-5 words
- uses spoon
18 months
- runs
- scribbles, 3 block tower
- 7-10 words, body parts
- copies parents in task
24 months
- throws ball
- 6-7 block tower
- two words combined
- turns book pages
3 years
- rides tricycle
- alternates feet upstairs
- copies a cricle
- uses min 250 words, 3 word sentences
- group play
- shares toys
- knows age & gender
4 years
- skips
- copies a square
- knows colors, songs, ask questions
- plays cooperative
5 years
- walks backwards
- grabs pencil
- prints letters
- prints first name
- abides by rules
vanderbilt scale
for ADHD in kids 6-19 y/o
Ages & stages questionairre
for cognitive/motor screening in children 4-60 months old
when do majority of the primitive reflexes dissipate?
4-6 months
which primitive reflex persists through life
parachute
Tanner Staging 1
M = no pubic hair, bone age < 12 y/o
F = no pubic hair, no breasts
Tanner stage 2
M = minimal pubic hair/voice changes, bone age < 12
F = minimal pubic hair, breast puds, bone age < 11
Tanner Stage 3 (pubescent)
M= pubic hair over penis, voice changes, bone age 13-14
F = pubic hair on mons, enlargement of breasts, axillary hair, bone age 12-13
Tanner Stage IV
M= adult pubic hair, axillary hair, bone age 13-14
F = adult pubic hair, areola enlargement, bone age 12-13
Tanner Stage V
M= as adult, bone age 14-16
F = adult, bone age 13-14
T/F in females pubic hair before breasts?
FALSE !!!
when does birth weight triple
12 months
when does birth length double
4 years
what level of bili is neurotoxic & causes kernicterus?
25 mg/dL
tx of pyloric stenosis
NG placemore for decompression, hydration, surgical pyloromyotomy
bilious vomiting
duodenal atresia
gold standard dx test for hirschsprung disease
rectal biopsy
abdominal pain, palpable sausage mass, currant jelly stools
intussusception
tx w/ hydrostatic or pneumatic enema (1st line)
MC involved site in intussusception?
ileocecal valve
bronchiolitis
clinical syndrome in kids < 2 y/o 2/2 to RSV infx.
sudden onset LRT sx that do not respond to mgmt of other respiratory conditions
foreign body aspiration
idiopathic avascular necrosis of the hip
Legg Calve Perthes
Growth Plate Fx
S: straight across (I)
A: above (II)
L: lower (III)
T: through (IV)
ER: eraser - crushed growth plate (V)
what type of salter harris fx is most common?
II (above)
if question stem indicates abuse
correct answer is typically contact CPS
bronchitis vs. bronchiolitis
bronchitis: older children, trachea & large airway infx & mucus presenting w/ persistent productive cough
bronchiolitis: 2 y/o, small airway infx. w/ wheeze, tachypnea, RD
tx of RDS
Antenatal therapy → steroids (24 hours before delivery)
Ventilation → CPAP, intubate (continuous positive pressure w/ NO)
Surfactant → endotracheal administration
O2 + intubation + CPAP + surfactant
Antenatal glucocorticoids given to mature lungs if premature delivery is suspected (between 24-36 weeks)
benefits of tx scarlet fever
prevents RF
** does NOT prevent APSGN**
tx of lime disease if < 8 y/o
amoxicillin
mcc meningitis
strep pneumo
[tx w/ ceftriaxone & vanco]
stoccato cough
chlamydia pneumonia
bad prognostic factor in JIA
RH factor
best first test in KD
echo + ekg
pt w/ scd c/o point tenderness on femur, fever and malaise
osteomyelitis (Mc bug is salmonella)
pt w/ scd w/ decreased hct and decreased retics
aplastic crisis
howell jolley body
sx of autosplenectomy
mcc of sepsis in scd pt
strep pneumo
tx of stroke in scd
exchange transfusion
Tx of HUSS
periotoneal dialysis
DO NOT give plt
when does plantar grasp extinguish?
12 mo
when does palmar grasp extinguish?
6 mo
when does babinski extinguish?
12-24 mo
empiric tx for neonatal meningitis
amp + gent
covers for GBS & E.coli
Blueberry Muffin Rash
rubella
vaccines at birth
hep B
vaccines 2-6 mo
babies Run Play HIDe
Hep B
RV
PCV13
Hib
IPV
Dtap
[no hep B at 4 months]
12 mo vaccines
1st MMR, Varicella, Hep A
[2nd dose @ 4-6 years]
4-6 year vaccines
2nd MMR, Varicella
11-12 y/o vaccines
HPV
Tdap
MCV
16 y/o vaccines
MCV
MCV before you’re free (to drive)
nasal polyps in young kid with chronic cough, SOB, hemoptysis?
CF
Tx of non-severe bronchiolitis
Supportive care
cough + fever
think pneumonia
most reliable predictors of pneumonia in pediatric patients
hypoxia & increased work of breathing
bronchial breathe sounds
sign of obstruction –> think pneumonia
MC etiology of afebrile pneumonia in children 1-4 mo
chlamydia trich. (staccato cough)
development of nonproductive cough after recent abx use should make you think?
possible progression of URI to pneumonia
first step after seeing microscopic hematuria on UA?
check how UA was obtained –> cath can lead to some blood
2-14 y/o boy w/ facial edema up to 3 weeks after strep
Cola-colored urine
(+) anti-streptolysin (ASO) titers
Low serum complement (C3)
post strep GN
MCC of GN in pediatric pt
IGA
occurs after 24-48 hr URI or GI infx.
systemic form of IgA nephropathy. It’s characterized by a purpuric skin rash, arthritis, and abdominal pain.
HSP
when does rooting reflex dissipate?
2-3 months
What are the five levels of alertness in infants?
Quiet sleep
active sleep
awake/drowsy
alert
crying.
MCC of bacterial meningitis for ages 3-10 y/o vs. >/= 10
3-10: strep pneumo
>10: N. meningitidis
hyperventilation effect on absence seizures?
leads to hypercapnia and respiratory alkolsis - increase in ph decreases neuronal excitability –> absence seizure trigger
Studies have shown that absence seizures are highly sensitive to changes in arterial CO2 levels
effects of feeding on wt gain in infants
breastfed = gain wt more rapidly in beginning
formula fed = gain weight slower in first 3-4 mo
when does baby roll back to front?
6 months
is there an age cut off for rear facing car seat recommendations?
NO - use until pt exceeds height/wt restrictions for safe use
labs of secondary hypogonadism
Low T or E
N FSH/LH
labs of primary hypogonadism
Low T or E
HIGH FSH/LH
flu vaccine recs for child with MILD egg allergy
2x dose of inactivated vaccine
** no assoc with severe rxn in pt with history of egg allergy
inactivated = shot
live/activated = mist
** both CI in children with severe egg allergy
URI x 10+ days w/o resolution of sx
amoxi-clav for bacterial sinusitis
Synovial fluid white blood cell count is typically elevated in the inflammatory range of 20,000 to 60,000 cells/µL
lyme arthritis
not as high as in septic arthritis
headache and fever for 3 days and erythematous PETECHIAL rash on her wrists and ankles
RMSF
give doxycycline
** common in NC, oklahoma, arkansas, MS
tx of CAH
hydrocortisone, fludrocortisone, sodium chloride
inspiratory stridor indicates?
d/o occuring ABOVE the vocal cords
think laryngomalacia
can children < 3 y/o get strep throat?
No - not considered pathologic because not enough tissue to infect/apart of normal flora
+/- data on giving amox for RF prevention
normal APGAR score
7+
chorioamnionitis
- maternal fever (100.4)
- significant maternal tachy (> 120)
- fetal tachycardia (> 160-180)
- IL-6 is possible marker for chorioamnionitis
- tx with ampicillin & gentamicin (careful w/ gentamicin bc of SNHL in pregnancy)
tx of TM performation
contaminated TM perf = ofloxacin drops
TM perf in setting of otitis media = PO abx
best initial evaluation of child abuse in ED in pt presenting with lethargy?
CT Brain
pt showing sx of AMS
murmur that is louder supine?
still (inocent) murmur