EOR 1

Question 1

Major Depressive Episode Criteria Etiology

Answer 1

Decreased catecholamines and serotonin

Question 2

Mixed Features Specifier

Answer 2

manic/hypomanic sx present during majority of days

Question 3

Peripartum onset specifier

Answer 3

sx onset during pregnancy or 4 weeks post delivery

Question 4

Name 4 SSRIs

Answer 4

Sertraline (Zoloft), Citalopram (Celexa), Escitalopram (Lexapro), Fluoxetine (Prozac)

Question 5

Time criteria for manic episode in Bipolar I

Answer 5

Lasts 1 weeks and has 3+ sx

Question 6

MD episode: __+ sx for at least _______

Answer 6

5+ sx for at least 2 weeks

Question 7

What is considered Rapid Cycling?

Answer 7

4+ mood episodes in 1 year

Question 8

4 tx options for Bipolar i

Answer 8

Lithium, Anticonvulsants, Atypical Antipsychotics, ECT

Question 9

DSM criteria for Bipolar II d/o

Answer 9

1+ major depressive episode and 1+ hypomanic episode (lasts at least 4 days w/ no significant impairment)

Question 10

Which has a better prognosis Bipolar I or II?

Answer 10

Bipolar II

Question 11

3 Major criteria for Persistent Depressive Disorder

Answer 11

1) Depressed mood for majority of time most days for 2+ years
2) Never sx free for >2 months
3) Never had manic/hypomanic episode

Question 12

Short term tx options for GAD

Answer 12

Benzodiazepines or augmentation w/ buspirone

Question 13

1st line tx for PTSD

Answer 13

SSRIs or SNRIs

Question 14

What drug could be helpful in PTSD for sx management?

Answer 14

Prazosin (alpha 1 blocker)

Question 15

Name 6 classes of antidepressants used for MDD

Answer 15

SSRIs, SNRIs, A2 blocker, DNRIs, Tricyclic Antidepressant, MAOIs

Question 16

What is the major concern w/ treating with SSRIs and MAOIs?

Answer 16

Serotonin Syndrome

Question 17

What is Serotonin Syndrome?

Answer 17

Autonomic instability, hyperthermia, hyperreflexia, seizures

Question 18

What is a major AE of MAOIs?

Answer 18

Hypertensive Crisis

Question 19

What must pts monitor while on MAOIs?

Answer 19

Tyramine intake

Question 20

What can Cyclothymic Disorder progress into?

Answer 20

Bipolar I/II

Question 21

What is the definition of panic disorder?

Answer 21

Recurrent, unexpected panic attacks w/o identifiable trigger

Question 22

What kind of drug is Abilify?

Answer 22

Mood stabilizer

Question 23

Is cortisol low or high in MDD?

Answer 23

High–> hyperactivity of HPA axis

Question 24

Most common SE complaints w/ SSRI?

Answer 24

GI upset, sexual dysfunction

Question 25

How long does it take for an antidepressant to reach its full therapeutic level?

Answer 25

4-6 weeks

Question 26

What is the GS therapy for pregnant women w/ manic episode?

Answer 26

ECT

Question 27

MC sleep disturbances a/w MDD

Answer 27

Difficulty falling asleep and early morning wake up

Question 28

3 Adjunct medications for MDD

Answer 28

Atypical Antipyschotics, T3 and T4

Question 29

Catatonia Specifier + tx

Answer 29

Features include catalepsy, purposeless motor activity, extreme negativism, bizarre postures, echolalia Tx--> these pts are especially responsive to ECT

Question 30

T/F major depression episodes are required for dx of Bipolar I

Answer 30

False--> Bipolar I involves episodes of mania and major depression but major depression is not required for dx

Question 31

Factors involved in development of Bipolar

Answer 31

Biological, environmental, psychosocial, genetic

Question 32

Pt w/ one or more major depressive episode w/ Full manic episode at any point in the past

Answer 32

Bipolar I

Question 33

GS for treatment of bipolar disorder

Answer 33

Lithium

Question 34

Dysthymia sx (CHASES)

Answer 34

poor Concentration, feelings of Hopelessness, poor Appetite or overeating, inSomnia or hypersomnia, low Energy or fatigue, low Self-esteem

Question 35

DSM criteria for dysthymia

Answer 35

depressed mood for 2 years (1 if child or adolescent) w/ at least 2 of CHASES and pt is never asx for >2 months; pt has never had a manic or hypomanic episode; may have major depressive episodes or meet criteria for MDD continuously