EOR 1 Flashcards

1
Q

Major Depressive Episode Criteria Etiology

A

Decreased catecholamines and serotonin

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2
Q

Mixed Features Specifier

A

manic/hypomanic sx present during majority of days

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3
Q

Peripartum onset specifier

A

sx onset during pregnancy or 4 weeks post delivery

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4
Q

Name 4 SSRIs

A

Sertraline (Zoloft), Citalopram (Celexa), Escitalopram (Lexapro), Fluoxetine (Prozac)

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5
Q

Time criteria for manic episode in Bipolar I

A

Lasts 1 weeks and has 3+ sx

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6
Q

MD episode: __+ sx for at least _______

A

5+ sx for at least 2 weeks

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7
Q

What is considered Rapid Cycling?

A

4+ mood episodes in 1 year

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8
Q

4 tx options for Bipolar i

A

Lithium, Anticonvulsants, Atypical Antipsychotics, ECT

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9
Q

DSM criteria for Bipolar II d/o

A

1+ major depressive episode and 1+ hypomanic episode (lasts at least 4 days w/ no significant impairment)

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10
Q

Which has a better prognosis Bipolar I or II?

A

Bipolar II

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11
Q

3 Major criteria for Persistent Depressive Disorder

A

1) Depressed mood for majority of time most days for 2+ years
2) Never sx free for >2 months
3) Never had manic/hypomanic episode

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12
Q

Short term tx options for GAD

A

Benzodiazepines or augmentation w/ buspirone

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13
Q

1st line tx for PTSD

A

SSRIs or SNRIs

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14
Q

What drug could be helpful in PTSD for sx management?

A

Prazosin (alpha 1 blocker)

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15
Q

Name 6 classes of antidepressants used for MDD

A

SSRIs, SNRIs, A2 blocker, DNRIs, Tricyclic Antidepressant, MAOIs

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16
Q

What is the major concern w/ treating with SSRIs and MAOIs?

A

Serotonin Syndrome

17
Q

What is Serotonin Syndrome?

A

Autonomic instability, hyperthermia, hyperreflexia, seizures

18
Q

What is a major AE of MAOIs?

A

Hypertensive Crisis

19
Q

What must pts monitor while on MAOIs?

A

Tyramine intake

20
Q

What can Cyclothymic Disorder progress into?

A

Bipolar I/II

21
Q

What is the definition of panic disorder?

A

Recurrent, unexpected panic attacks w/o identifiable trigger

22
Q

What kind of drug is Abilify?

A

Mood stabilizer

23
Q

Is cortisol low or high in MDD?

A

High–> hyperactivity of HPA axis

24
Q

Most common SE complaints w/ SSRI?

A

GI upset, sexual dysfunction

25
Q

How long does it take for an antidepressant to reach its full therapeutic level?

A

4-6 weeks

26
Q

What is the GS therapy for pregnant women w/ manic episode?

A

ECT

27
Q

MC sleep disturbances a/w MDD

A

Difficulty falling asleep and early morning wake up

28
Q

3 Adjunct medications for MDD

A

Atypical Antipyschotics, T3 and T4

29
Q

Catatonia Specifier + tx

A

Features include catalepsy, purposeless motor activity, extreme negativism, bizarre postures, echolalia

Tx–> these pts are especially responsive to ECT

30
Q

T/F major depression episodes are required for dx of Bipolar I

A

False–> Bipolar I involves episodes of mania and major depression but major depression is not required for dx

31
Q

Factors involved in development of Bipolar

A

Biological, environmental, psychosocial, genetic

32
Q

Pt w/ one or more major depressive episode w/ Full manic episode at any point in the past

A

Bipolar I

33
Q

GS for treatment of bipolar disorder

A

Lithium

34
Q

Dysthymia sx (CHASES)

A

poor Concentration, feelings of Hopelessness, poor Appetite or overeating, inSomnia or hypersomnia, low Energy or fatigue, low Self-esteem

35
Q

DSM criteria for dysthymia

A

depressed mood for 2 years (1 if child or adolescent) w/ at least 2 of CHASES and pt is never asx for >2 months; pt has never had a manic or hypomanic episode; may have major depressive episodes or meet criteria for MDD continuously