EOM Flashcards
What polymyalgia Rheumatica ?
Inflammation disorder that causes muscle pain
What are key sxs of Polymyalgia Rheumatica (PMR)?
morning stiffness lasting 48 hours. Aching/pain in neck, bilateral shoulders, low back, hips & thighs.
SXS MUST BE ONGOING FOR 2WKS
What Dx finding will be seen in PMR?
Elevated ESR >100
How do you tx PMR?
Prednisone 15 mg/day
What is Giant Cell Arteritis or Temporal Arteritis ?
Immune Mediated damage to the carotid arteries. Damage lead to inflammation and thrombus formation + instability of the vessels walls prone to aneurysms.
Which artery is most commonly affected in Giant Cell Arteritis or Temporal Arteritis?
Temporal artery is commonly affected
SXS of Giant Cell Arteritis or Temporal Arteritis ?
New HA (unilateral in temporal area)
Pain when brushing hair.
·Vision loss (ophthalmic artery blockage) Pain/stiffness in hips & shoulders
Fever & weight loss
Pain w chewing food (jaw claudication)
Dx for Giant Cell Arteritis or Temporal Arteritis?
Temporal Artery Biopsy
Elevated ESR >100
Bruit heard w temporal accusation
Tx for Giant Cell Arteritis or Temporal Arteritis?
Vision intact-> prednisone -> 40-60mg/day
Vision loss-> methylprednisolone 500-1000 IV/day for 3 days
What is Hypertrophic Cardiomyopathy ?
Asymmetric thickening of the myocardium. Septum thicker >3omm than the rest of the ventricle
What causes Hypertrophic Cardiomyopathy ?
Autosomal dominant mutation of the protein that encodes sarcomere.
–> Beta-myosin heavy chain
–> myosin-bindin protein C
Which pts with Hypertrophic Cardiomyopathy should get a ICD?
1) septal wall thickness >30mm
2)unexplained syncope
3) fail to increase or decrease BP by 20 mm Hg
4) LVEF is less than or equal to 35%
SXS of Hypertrophic Cardiomyopathy
dyspnea on exertion, presyncope,syncope, fatigue, edema, orthopnea, paroxysmal nocturnal dyspnea
Dx for Hypertrophic Cardiomyopathy?
ECG
Echocardiogram
Tx Hypertrophic Cardiomyopathy?
B Blockers (avoid meds that decrease preload & afterload)
implantable cardioverter-defibrillator
abalation of septum
anticoag w A fib
Hypertophic cardiomyopathy can cause which type of arrhythmia?
Ventricular arrhythmias