Enzymes CH. 3

Question 1

NAD+

Answer 1

Nicotinamide Adenine Dinucleotide

Question 2

NADP+

Answer 2

Nicotinamide Adenine Dinucleotide Phosphate

Question 3

Examples of Cosubstrates

Answer 3

NAD+ & NADP+

Question 4

Holoenzyme

Answer 4

Catalytically active enzyme - cofactor

Question 5

Apoenzyme

Answer 5

The enzymatically inactive protein resulting from removal of haloenzyme

Question 6

Transition State

Answer 6

Highest free energy

Question 7

Reaction coordinate

Answer 7

Reactants generally approach one another along the path of minimum free energy

Question 8

X++

Answer 8

Represents transition state

Question 9

Delta G ++

Answer 9

Free energy of the transition state.
Free energy of activation

Question 10

Greater the value delta G ++

Answer 10

Slower the reaction rate

Question 11

Rate determining step

Answer 11

In multiple rxn, The step with the highest transition state free energy acts as bottleneck

Question 12

Prosthetic group

Answer 12

Tightly bound coenzyme

Question 13

Cofactor

Answer 13

Metal ion, like magnesium or organic substance

Question 14

Proenzyme or Zymogen

Answer 14

Produced in Inactive form , that must go activation for it to function

Question 15

Forms of enzyme control

Answer 15

Activation of inactive form of enzyme and inhinibition

Question 16

Competition inhibition

Answer 16

Another species competes with substrate to interact with active site on enzyme

Question 17

Non competitive inhibition

Answer 17

Other species binds to other site other than active site

Question 18

Oxidoreductases

Answer 18

Redox rxns

Question 19

Transferases

Answer 19

Transforms of functional groups

Question 20

Hydrolysis

Answer 20

Hydrolysis

Question 21

Lyases

Answer 21

Additions to double bonds or formation of one

Question 22

Isomerases

Answer 22

Isomerization of molecules

Question 23

Ligases

Answer 23

Joining of 2 molecules