Enzymes and Regulation Flashcards by Victoria Glascott

Q

Hexokinase - Inhibitor

A

G-6-P

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Q

Glucokinase - Activator

A

Glucose, Fructose-1-P, Insulin

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Q

Glucokinase - Inhibitor

A

Glucagon, Fructose-6-P

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Q

Pyruvate Kinase - Activator

A

Insulin, Fructose-1,6-BP

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Q

Pyruvate Kinase - Inhibitor

A

Alanine, ATP, Glucgon

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Q

PEP Carboxykinase - Activators

A

Cortisol, Glucagon, THroxine

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Q

Fructose-1,6,-Biphosphatase - Activator

A

Citrate, Cortisol

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Q

Fructose-1,6,-Biphosphatase - Inhibitor

A

High [AMP], Fructose-2,6-BP

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Q

G-6-Phosphatase - Activator

A

Cortisol

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Q

Pyruvate Kinase - Activators

A

Insulin, F-1,6-BP

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Q

Pyruvate Kinase - Inhibitors

A

Alanine, ATP, Glucagon

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Q

Pyruvate Carboxylase - Activators

A

Acteyl-CoA, Cortisol

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Q

Pyruvate Carboxylase - Inhibitiors

A

ADP

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Q

PEP Carboxykinase - Activator

A

Cortisol, Glucagon, Throxine

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Q

Fructose-1,6-Bisphosphatase - Activator

A

Citrate, Cortisol

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Q

Fructose-1,6-Bisphosphatase - Inhibor

A

High [AMP], F-2,6-BP

Q

ATP Synthase - Inhibitors

A

Oligiomyocin, Uncouplers (Thermogenin or DMP)

Q

Citrate Lyase - Activator

A

Glucose, Insulin

Q

Acetyl-CoA Carboxylase - Activator

A

Citrate

Q

Acetyl-CoA Carboxylase - Inhibitors

A

Glucagon, Epinephrine, high [AMP] Palmitate, PUFA

Q

Fatty Acid Synthase - Activator

A

Citrate

Q

Fatty Acid Synthase - Inhibitors

A

PUFA

Q

Carnitine Acyltransferase - Inhibitor

A

Manonyl-CoA

Q

Acyl-CoA Desaturase

A

Insulin (Creates Double Bond in FA)

Acyl-CoA Desaturase

PUFA (Creates Double Bond in FA)

DHFR - Inhibitor

Methotrexate

Thymidyial Synthase - Inhibitor

Fluoracil

Carbomyl Phosphate Synthase - Activator

PRPP

Carbomyl Phosphate Synthase - Inhibitor

UMP, Purines

Xanthine Oxidase - Inhibitor

Allopurinol - (helps with GOUT)