Enzymes

Question 1

Reversible inhibition

Answer 1

Characterized by rapid dissociation of the enzyme-inhibitor complex

Question 2

Competitive inhibition

Answer 2

• Enzyme binds the substrate or inhibitor but not both.
• Often resembles the substrate and binds to the active site of the enzyme. Substrate can not bind the same active site
• ** Competitive inhibitor diminishes the rate of catalysis by reducing the proportion of enzyme molecules bound to a substrate**
• Can be relieved by increasing substrate concentration

Question 3

Uncompetitive inhibition

Answer 3

Substrate dependent inhibition in that the inhibitor binds only to the enzyme-substrate complex

• uncompetitive inhibition can be overcome by the addition of more substrate

Question 4

Irreversible Inhibitor

Answer 4

Dissociates very slowly from its target enzyme because it has become tightly bond to the enzyme, either covalently or non-covalently.