Enzymes Flashcards
What do Enzymes do?
Speed up metabolic reactions
What is an enzyme made out of?
Proteins
Can an Enzyme be consumed in a reaction?
No
Lock and Key model
A perfect fir for the enzyme and substrate
Induced fit model
Enzyme active site changes shape to fir substrate
How does temperature affect the reaction rate of an enzyme?
- Temp too low = less kinetic energy (less enzyme-substrate complexes) less reaction rate
- Temp to high = active site denature and substrate does not fit
How does PH affect the rate of reaction in an enzyme?
PH too high/low = denatured active site meaning substrate does not fit
Biochemical pathway
A sequence of different reactions catalysed by different enzymes
Feedback inhibition
Final product of biochemical pathway turns into non competitive inhibitor for first enzyme to stop too much production
Competitive inhibitor
Binds to active site
slows reaction rate
can be stopped if enough substrate added
Non competitive inhibitor
Binds to allosteric site
Changes active site shape
substrate can’t get through
Cofactors/Coenzymes
Bind to active site to allow substrate access
Substrate Concentration
Rate of reaction increase until all active sites are full
Enzyme concentration
Rate of reaction increases until there is not enough substrate
