enzyme classification and nomenclature

Question 1

• Joins 2 substrate molecules, coupled with breaking of pyrophosphate bond in ATP
• Ab + C → A–C + b
• Glutathione Synthetase (GSH-S)

Answer 1

ligases

Question 2

• Catalyze hydrolysis of various bonds
• A–B + H2O → A–OH + B–H
• Eg:Amylase (AMY), Lipase (LPS), Phosphatase (ACP)

Answer 2

hydrolases

Question 3

• Removal of groups from substrates without hydrolysis; product remain double bonds
• ATP → cAMP + PPi
• Fructose biphosphate aldolase (ALS)

Answer 3

lyases

Question 4

• Catalyze redox rxn. between 2 substrates
• A - + B → A + B-
• E.g: Dehydrogenase (LD)

Answer 4

oxidoreductase

Question 5

Catalyze the transfer of a group (Methyl, Carboxyl, Phosphate) between 2 substrates (A-X + B → A + B-X)

Answer 5

transferase

Question 6

• Interconversion of geometric, optical or positional isomers
• A → B

Answer 6

isomerases