Enteropathic and Reactive arthritis Flashcards
1
Q
What is Enteropathic arthritis?
A
- chronic, inflammatory arthritis associated with IBD
2
Q
Apart from IBD, what other diseases are associated with EA?
A
- GI bypass
- Coeliac
- Whipple’s disease
3
Q
How would you Mx EA?
A
- often improves with IBD treatment
- DMARDs for resistant case
4
Q
What is Reactive Arthritis?
A
- Condition in which arthritis and otehr clinical manifestations occur as an autoimmune response to infection elswhere in body
5
Q
Infections involving which part of the body typically cause Reactive atrhritis?
A
- GI
- GU
6
Q
What are the clinical features of Reactive Arthritis?
A
- Asymptomatic
- Iritis
- Keratoderma blenorrhagica (brown raised plaques on soles)
- Circinate balanitis
- mouth ulcers
- enthesitis
- Reiter’s syndrome
7
Q
What is Reiter’s syndrome?
A
- urethritis
- arthritis
- conjunctivitis
8
Q
What test would you perform for Reactive Arthritis?
A
- Bloods
- High ESR, CRP
- infectious serology
- Stool culture
- Sexual health review
- Xray
- enthesitis
- periosteal reaction
9
Q
How would you Mx Reactive arthritis?
A
- Split affected joints acutely
- NSAIDs
- Local steroids injection
- Sulfasalazine / methotrexate if sx > 6months
10
Q
What are the common associations of HLA B27 gene?
A
- Ankylosing spondylitis (highest association)
- Reactive arthritis
- Psoriatic arthritis
- Enteric arthropathy (lowest association)
11
Q
What are the common features of seronegative spondyloarthropathies?
A
- associated with HLA-B27
- rheumatoid factor negative
- peripheral arthritis, usually asymmetrical
- sacroiliitis
- enthesopathy: e.g. Achilles tendonitis, plantar fasciitis
- extra-articular manifestations: uveitis, pulmonary fibrosis (upper zone), amyloidosis, aortic regurgitation
12
Q
What are HLA-B27 antigen associated with?
rememebr *PAIR
A
- Psoriatic arthritis
- Ank Spond
- IBD
- Reactive art
