Enterobacteriaceae Flashcards
General Characteristics of Enteric Family
GNRs Ferment glucose Oxidase negative * Reduce nitrate to nitrite Motile * Facultative anaerobes
The two major types of Enterics (clinical significance)
Opportunistic pathogens
Primary pathogens
Which genera of Enterobacteriaceae are primary pathogens?
Salmonella
Shigella
Yersinia
Gastrointestinal Escherichia coli types
ETEC EPEC EIEC EHEC DAEC EAEC
Clinical types of E. coli
Uropathogenic
Gastrointestinal pathogens
Extraintestinal pathogens
Extraintestinal infections caused by E. coli?
Meningitis and septicemia
Most common in neonates and young children
Characteristics of Escherichia coli?
Lactose fermenters (NOT EIEC) IMVC ++- - Urease- DNAse- PAD- H2S- O, H, and K antigens Beta-hemolytic
Disease caused by EPEC?
“Enteropathogenic”
Traveler’s diarrhea
LT and ST toxins
Disease caused by EIEC?
“Enteroinvasive” Dysentery Stool with pus, mucus, and blood *NLF and nonmotile *Lysine decarboxylase -
Infection caused by EPEC?
“Enteropathogenic” Infantile diarrhea Adhesions Mucus diarrhea NO blood Vomiting
Infections caused by EHEC?
“Enterohemorrhagic” E. coli O157H17 Hemorrhagic diarrhea HUS Verotoxin 1/2 or “shigatoxin” (STEC) Bloody and mucus diarrhea with no pus *Non-sorbitol fermenting
Characteristics of Klebsielleae
Opportunistic/nosocomial H2S - Urease - IMVC - - ++ Members: Enterobacter, Serratia, Klebsiella
Klebsiella genera unique characteristic?
NONMOTILE
Clinically significant Klebsiella species and infections?
K. pneumoniae: LRT, UTI, liver abscess, and wound
K. oxytoca: indole +
