Enteric Infections Lecture 13 Flashcards
Watery Diahrrea. Location and organisms
-Located in the small intestine. Cholera, Enterotoxigenic E coli, Giardia, Clostriduim Perringes
Dysentery. Location and Organisms
-Located in the Colon. Presence of blood and puss in the stool. Shigella, Campylobacter, E Coli Enterohemorrhagic, Salmonella (some strains)
Enteric Fever
-Can be watery or blood/pus, but with expansion of bacteria thoughout GI and possibly other systems. With presence of fever. Salmonella typhi, Yersinia hemolyticus.
Vibrio Cholera
-Contaminated drinking water. Rice water stools. ADP ribosylation of Adenylate cyclase leading to increased cAMP and excretion of K, Cl, HCO3 and loss of water. Infects the small intestine
Vibrio Hemolyticus
-Most common cause of food poisoning in Japan, undercooked or raw seafood and shellfish. Causes self limited watery diarrhea of small intestine. Severe problems in those with cirrhosis.
Enterotoxigenic E Coli
-Most common cause of travelers diarrhea (Shigella is second) self limiting infection in small intestine. Also E Coli Aggregative and pathogenic.
Giardia Lambelli
-Picked up from unpurified drinking water camping or day cares. Parasite. Can become chronic. Includes bloating aches and fever.
Shigella sp
-Soneii is most common, commonly picked up at day care centers. Causes dysentry and blood/pus in stool. Infects the large intestine.
Clostridium dificile
- Most common hospital acquired, spores are very contagous, can arise because of antibiotic therapy. Usually self limited but may have to treat.
Campylobacter
-Causes dysentery with blood and pus in stool. Common source of food poisoning. Risk of Rieters (arthritis) and Guillen-bare.
Salmonella
-Infection can be different depending on strain. Watery, dysentery, or enteric fever. S. typhi causes epidemic typhoid fever that causes fever and sustained bacteremia. There can be a pulse/fever mismatch with a normal pulse rate and elevated fever.
Yersinia enterolitica
-Causes enteric fever. Often mimics appendicitis with pain.
Inflammatory
-Bacterial etiology with possible growth
Noninflammatory
-Preformed toxin, viruses, or non microbial source.