ENT - The Thyroid Gland Flashcards

1
Q

Describe the arterial supply to the thyroid gland. Which structures are closely associated?

A
  1. superior thyroid artery (1st br of external carotid a.) - associated with external laryngeal n.
  2. inferior thyroid artery (br of thyrocervical trunk) - associated with recurrent laryngeal n.
  3. +/- variant thyroid ima artery
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2
Q

A 50yo lady presents with an enlarged thyroid gland. What is your differential diagnosis?

A

Goitre only:

  • multinodular goitre
  • iodine-deficiency (simple goitre)
  • thyroid cancer

Goitre + metabolic dysfunction:

  • Grave’s disease (simple goitre)
  • toxic multinodular goitre
  • toxic adenoma
  • Hashimoto’s disease
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3
Q

A 50yo lady presents with a single thyroid nodule detected on USS. What Ix should be performed?

A
  1. TFTs
  2. USS-guided FNA
  3. if any diagnostic doubt: diagnostic hemithyroidectomy
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4
Q

What is your differential diagnosis for a single thyroid nodule?

A
  1. non-neoplastic: colloid or cystic
  2. benign follicular adenoma
  3. malignant neoplasms:
    - papillary (70%)
    - follicular (20%)
    - medullary (5%, from parafollicular C cells): usually in MEN, increased calcitonin with normal calcium
    - anaplastic (usually in elderly females): rapid painful enlargement of thyroid, airway/voice/swallowing problems, poor prognosis
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5
Q

What is the usual Tx for papillary thyroid cancer?

A
  1. total thyroidectomy +/- neck dissection
  2. +/- post-op radioiodine
  3. lifelong thyroid hormone replacement at TSH-suppressing doses
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6
Q

Suggest possible complications of thyroid surgery.

A
  1. post-op haemorrhage
  2. airway obstruction:
    • secondary to haemorrhage (most frequent cause in 1st 24hrs)
    • secondary to bilateral vocal cord palsy
  3. vocal cord palsy: due to RLN palsy causing hoarseness if unilateral or aphonia + airway obstruction if bilateral
  4. hypocalcaemia due to parathyroid trauma or devascularisation: presents acutely at 24-48hrs as laryngeal stridor + airway obstruction, QT prolongation + cardiac arrest
  5. post-op infection
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