ENT Part I Flashcards
How many muscles of the eye are there?
6
These muscles are innervated by the oculomotor nerve
Oculomotor nerve = CN III
- Superior rectus
- medial rectus
- inferior rectus
- inferior oblique.
This muscle is innervated by the abducens nerve
abducens nerve = CN VI
- Lateral rectus (LR6)
- Moves the eye down and outward.
This muscle is innervated by the trochlear nerve
trochlear nerve = CN IV
- Superior oblique (SO4)
- moves the eye down and out
Functions of the oculomotor nerve.
- Innervates 4 of the eye muscles
- superior rectus
- medial rectus
- inferior rectus
- inferior oblique
- Also causes pupillary constriction and eyelid opening.
Innervation of the trigeminal nerve
3 branches total, but two SENSORY branches for the eye
-
Ophthalmic branch
- Innervates upper eyelid, conjunctiva, and cornea
-
Nasociliary branch of the ophthalmic nerve
- sensory to the medial canthus, lacrimal sac, and ciliary gangion (cornea, iris, and ciliary body)
- Also reulates oculocardiac reflex
- Maxillary branch - Sensory to lower lid
Topical anesthesia eye drops do a great job at blocking this, but not this
- Good for blocking the trigeminal nerve, which innervates the cornea.
- Bad at blocking the eyelids = Need extra anesthesia to relax the lids for traction.
Injury to this nerve can result in total blindness
-
Optic nerve (CN II) which is part of the optic chiasm
- nerve, artery, and sympathetic nerves
Where is aqueous humor produced?
-
2/3 is made in the posterior chamber by the ciliary body.
- Once produced, it is actively moved from the posterior to the anterior chamber via an active sodium pump mechanism.
- 1/3 is produced by passive filtration through vessels in the iris
How fast is aqueous humor produced?
2uL/min
This is the same as 0.12mL per hour.
Sooooo not very fast!
How is aqueous humor eliminated?
- It drains out of the eye through a spongy tissue called the trabecular meshwork.
- From the meshwork, it drains into Schlemm’s canal and the episcleral venous system located in the anterior chamber, eventually ending up at the SVC and RA.
What is normal IOP and what factors determine it?
Normal IOP is 10-20mmHg
-
4 players in determining IOP:
- Production of aqueous humor
- Drainage of aqueous humor
- Changes in the choroidal blood volume or pressure
- EOM (extraocular muslce) tone
The globe of the eye is a pretty non-compliant structure, the volume of the compartments is fixed, with these two exceptions
- Aqueous fluid
- Choroidal blood volume.
These volumes can change and regulate the IOP.
These factors can increase IOP
Major problem if the globe of the eye is exposed (in eye trauma) because it will lead to spillage of contents of the eye. Gross!
- Drugs:
- Ketamine
- Sux (up to 8mmHg increase in IOP d/t fasciculations.
- Other:
- Position changes
- coughing
- valsalva maneuver
- straining, vomiting
- HTN
- injection of local anesthesia
- laryngoscopy
- hypercarbia
- lid pressure, eye compression, forceful eyelid squeeze
These factors will decrease IOP
Drugs:
- Most anesthetic drugs
- NDMRs
- Hypertonic solutions (3%NS, mannitol, etc)
Other:
- Hypotension
- hypothermia
- hyperventilation (low CO2 –> similar to decreasing ICP!)
Examples of topical ophthalmic drugs and their effects
-
Acetazolamide
- Used to tx glaucoma
- Induces diuresis
- May cause K+ depletion
- want preop labs
-
Ecothiophate
- Used to tx glaucoma
- Topical anticholinesterase
- maintains miosis
- May cause inhibition of plasma cholinesterase;
- caution with succinylcholine and toxicity with ester-type local anesthetics
-
Phenylephrine - Alpha agonist;
- causes mydriasis
- Associated with severe HTN
-
Acetylcholine - Cholinergic drugs
- constrict pupil
- Can cause bradycardia and acute bronchospasm
-
Timolol - Used in the tx glaucoma
- Topical beta blocker
- May cause bradycardia, bronchospasm, CHF
-
Ketorolac and Diclofenac
- Both are NSAIDs - Used for inflammation
- Mitomycin C - Chemotherapeutic drug
- Atropine = Pupil dilation
- Cyclopentolate = Potent pupil dilation
This glaucoma med must be stopped 4-6 weeks prior to surgery
Ecothiophate
- topical anticholinesterase
-
inhibition of plasma cholinesterases d/t systemic absorption
- sux (prolonged NMB)
- ester-type LA toxicity (because the ESTERs and metabolized by plasma ESTERases)
This chemo agent is used ophthalmically to promote smooth healing of the eye
Mitomycin C.
- prevents excessive cellular proliferation results in scarring.
Nerves that mediate the oculocardiac reflex (OCR)
- Trigeminal (afferent)
- Vagal (efferent)
S/S of the OCR
- Bradycardia
- AV block
- ventricular ectopy
- asystole
What triggers the OCR?
- Pressure on the globe
- pain
- traction on the EOMs
- retrobulbar block
- eye trauma
- hypoventilation
- ( hypercarbia increases IOPs)
OCR occur most often during this type of surgery****
Strabismus surgery
(due to manipulation of the EOMs) This was italicized on the ppt. Possible test question.
How can you try to prevent the OCR, and how do you treat the OCR if it happens?
Prevention:
- Maintain normal EtCO2
- Pretreat with anticholinergics like Glyco (this is not normally necessary)
Treatment:
- Tell surgeon to stop the stimulus. Let them know what is happening.
- Assess their ventilatory status (what is their EtCO2 looking like?) –> may want to hyperventilate
- Atropine if necessary in 7mcg/kg increments -
- Injection of LA into the EOMs
What is a big thing you need to assess for before an eye surgery?
- Is the patient able to cooperate and lie still?
- If not, do a general anesthetic.
- Conditions it is difficult to lie supine and lie still:
- SOB, OSA, chronic cough, nasal drip, reflux, nausea, Parkinson’s, Alzheimer’s or claustrophobia, mentally disabled, back pain, pediatric patients
What to tell you patient regarding before eye surgery?
- continue their home medication regimen
- Let them know they need to lie still and may be awake for the procedure.
- Avoid overhydration –> awake and may have to pee
Goals of anesthesia for eye surgery
- Safety (ability to manage airway with limited access),
- control HTN
- avoid overhydration
- akinesia
- analgesia
- taking steps to avoid the OCR
- preventing increase in IOP
- smooth emergence (avoiding retching, vomiting, coughing etc than can increase IOP and rupture stitches)
- awareness of drug interactions (ecothiophate and sux/ester-LAs)
Advantage of regional over general anesthesia for eye surgeries
- Provides good analgesia
- Less occurance of N/V
- Faster recovery and discharge
- Cheaper
Anesthesia/sedation for retrobulbar block
- Usually, patient sedated for the block and then wake them back up.
- They are supine with HOB up 10-15 degrees. Nasal cannula in place with ASA monitors.
-
Propofol can be given in small increments (20mg).
- no analgesia = patient may startle on needle insertion.
-
Remifentanyl is another option (.3-.5mcg/kg).
- Lasts 2-5 minutes, long enough for placement of the block.
- Can give midazolam in addition to these two meds depending on the pt’s age.
- Infusions are not necessary because we want the patient to be aware an unobtunded during the procedure.