ENT - neck lumps Flashcards
What are the borders of the triangles in the neck?
These two triangles are on either side of the sternocleidomastoid muscle.
The borders of the anterior triangle are:
- Superior - mandible
- Medial - Midline of the neck
- Lateral - Sternocleidomastoid
The borders of the posterior triangle are:
- Inferior - Clavicle forms the inferior border
- Posterior - Trapezius
- Lateral - Sternocleidomastoid
Differential diagnosis of neck lumps in adults
Skin abscess
Lymphadenopathy (enlarged lymph nodes)
Tumour (e.g., squamous cell carcinoma or sarcoma)
Lipoma
Goitre (swollen thyroid gland) or thyroid nodules
Salivary gland stones or infection
Carotid body tumour
Haematoma (a collection of blood after trauma)
Thyroglossal cysts
Branchial cysts
On examination, lump may be
Pulsatile - e.g. carotid body tumour
Movement with swallowing (e.g. thyroid lumps) or sticking their tongue out (e.g. thyroglossal cysts)
Transilluminates with light (e.g., cystic hygroma – usually in young children)
General examination findings…
Ear, nose and throat infections (e.g., reactive lymph nodes)
Weight loss (e.g., malignancy or hyperthyroidism)
Skin pallor and bruising (e.g., leukaemia)
Focal chest sounds (e.g., lung cancer)
Clubbing (e.g., lung cancer)
Hepatosplenomegaly (e.g., leukaemia)
Neck lump 2WW referral criteria
An unexplained neck lump in someone aged 45 or above
A persistent unexplained neck lump at any age
Consider an urgent ultrasound scan if
Lump is growing in size:
- within 2 weeks in patients 25 and older
- within 48 hours in patients under 25
If this suggests soft tissue sarcoma - 2WW referral
Investigations in neck lumps
Bloods (not every neck lump):
- FBC and blood film for leukaemia and infection
HIV test
Monospot test or EBV antibodies for infectious mononucleosis
Thyroid function tests for goitre or thyroid nodules
Antinuclear antibodies for systemic lupus erythematosus
Lactate dehydrogenase (LDH) is a very non-specific tumour marker for Hodgkin’s lymphoma
Imaging - first line is USS usually
- Also could do MRI/CT
- Nuclear medicine scan (e.g., for toxic thyroid nodules or PET scans for metastatic cancer)
Biopsy may be needed
What can cause lymphadenopathy in the neck?
Reactive e.g. URTI, tonsillitis
Infected LNs e.g. TB, HIV, infectious nucleosis
Inflammatory conditions e.g. SLE, sarcoidosis
Malignancy - lymphoma, leukaemia or metastasis
What is infectious mononucleosis?
EBV virus infection (spread by bodily fluid contact, especially saliva)
This presents with:
- Fever
- Sore throat
- Fatigue
- Lymphadenopathy
Mononucleosis can present with an intensely itchy maculopapular rash in response to amoxicillin or cephalosporins.
What is the investigations and management of mononucleosis?
Monospot test - first line investigation
- Can also test for IgM IgM (acute infection) and IgG (immunity) to EBV
Management is supportive
- Avoid alcohol (risk of liver impairment)
- Avoid contact sport (for at least a month) - due to a risk of splenic rupture
How does lymphoma present?
Lymphadenopathy is the key symptom
B cancer symptoms
Reed sternberg cell on LN biopsy in Hodgkin’s
How does thyroid pathology present?
Will move with swallowing
Goitre - generalised swelling:
- Graves disease (hyperthyroidism)
- Toxic multinodular goitre (hyperthyroidism)
- Hashimoto’s thyroiditis (hypothyroidism)
- Iodine deficiency
- Lithium
Individual lumps:
- Benign hyperplastic nodules
- Thyroid cysts
- Thyroid adenomas (benign tumours the can release excessive thyroid hormone)
- Thyroid cancer (papillary or follicular)
- Parathyroid tumour
Symptoms of hypo or hyperthyroidism
Salivary glands and what can enlarge them
3 salivary glands:
- Parotid glands
- Submandibular glands
- Sublingual glands
3 main reasons for enlargement:
- Stones blocking drainage (sialolithiasis)
- Infection
- Tumours (benign or malignant)
Carotid body tumours - what are they?
The carotid body is just above the carotid bifurcation
Excessive growth of glomus cells in the carotid body.
Most are benign
Presentation of carotid body tumours
Slow growing lump that is:
- Near the angle of the mandible (anterior triangle)
- Painless
- Pulsatile
- Bruit on auscultation
- Mobile side to side but not up and down
May compress CN9-12 nerves
CN10 compression can cause Horner syndrome
- Ptosis
- Miosis
- Anhidrosis (loss of sweating)