ENT Flashcards
What is tonsillitis?
Inflammation due to infection of the tonsils
What are the most common causative organisms of tonsillitis?
Mostly viral- HSV, adenovirus, rhinovirus, influenza, coronavirus, RSV, EBV
Bacterial- staph aureus, strep pneumoniae, mycoplasma pneumoniae
GpA B-haemolytic strep (Strep pyogenes)
What criteria can be used to assess the need for antibiotics in tonsillitis?
FeverPAIN or CENTOR
What are the FeverPAIN criteria?
Fever > 38 Purulence- exudate Attends rapidly- 3 days or less severely Inflamed tonsils No cough or coryza 2 or more- consider antibiotics
What are the CENTOR criteria?
Likelihood of a bacterial infection in patients with sore throat 1. Hx of fever 2. Tonsillar exudate 3. Tender anterior cervical adenopathy 4. Absence of cough Age < 15 (+1) or > 44 (-1)
Management of tonsillitis
Fluids, analgesia
Abx- Phenoxymethylpenicillin V for 10 days
What is the most common causative organism for Glandular fever/Infectious mononucleosis?
EBV
10% CMV
Presentation of Glandular fever/Infectious mononucleosis
Fever, malaise, headache, sore throat, photophobia, red/swollen tonsils with white patches, lymphadenopathy, cough, splenomegaly, abdo pain, nausea
Investigations for Glandular fever/Infectious mononucleosis
Monospot/EBV serology
Throat swab
Management of Glandular fever/Infectious mononucleosis
Usually self-limiting
Causes of 8th nerve lesions
Paget’s disease of bone, Meniere’s disease, Herpes zoster, neurofibroma, acoustic neuroma, CVA, lead, aspirin, furosemide
Presentation of 8th nerve lesions
Unilateral sensorineural deafness and tinnitus
Aetiology of conductive deadfness
Impediment to passage of sound waves between external ear and footplate of stapes
Aetiology of sensorineural deafness
Fault in cochlea or cochlear nerve
What is presbyacusis?
Age-related hearing loss
What is the most common cause of acquired deafness??
Otitis media with effusion
Is air or bone conduction better in conductive and sensorineural deafness?
Conductive: air > bone
Sensorineural: air + bone conduction bad
Causes of conductive hearing loss
Obstruction of external ear canal: wax, inflammatory oedema, debris, atresia, FB
Perforated TM
Fixation/Discontinuity of ossicular chain- infection/trauma
Middle ear effusion
Causes of sensorineural deafness
Bilateral progressive loss- presbyacusis, drug ototoxicity, noise damage
Unilateral progressive loss- Meniere’s disease, acoustic neuroma
Sudden loss- trauma, viral, CVA, acoustic neuroma, barotrauma
What is Acoustic neuroma/Vestibular Schwannoma?
Tumour of vestibulocochlear nerve arising from Schwann cells of the nerve sheath
Slow-growing but mass effect
Risk factors for Acoustic neuroma/Vestibular Schwannoma
Neurofibromatosis type 2
Radiation
Presentation of Acoustic neuroma/Vestibular Schwannoma
Unilateral sensorineural hearing loss, tinnitus, impaired facial sensation, balance problems
Later- facial pain, earache, ataxia
Investigation of suspected Acoustic neuroma/Vestibular Schwannoma
MRI
Management of Acoustic neuroma/Vestibular Schwannoma
Microsurgery
Stereotactic radiotherapy
What is Otitis Externa?
Inflammation of the outer ear
Most common causative organism of Otitis Externa
Pseudomonas aeruginosa
Also fungal- Aspergillus/Candida
Risk factors for Otitis Externa
Hot humid climates, swimming, immunocompromise, DM, over-cleaning, eczema, obstruction of meatus
Presentation of Otitis Externa
Pain + itching, hearing loss, ear canal erythema, oedema, exudate, mobile tympanic membrane, pain with movement of tragus, pre-auricular lymphadenopathy
Management of Otitis Externa
Acute: topical drops, oral/IV Abx- Flucloxacillin or Ciprofloxacin in diabetes
Chronic: Acetic acid + corticosteroid drops; Fungal: Clotrimazole drops
What is Malignant Otitis Externa?
Osteomyelitis of EAM + bony tympanic plate (necrotising)
Presentation of malignant Otitis Externa
Severe unremitting otalgia, purulent aural discharge, granulaitons
Management of malignant Otitis Externa
Quinolones 6-8wks
Complications of Otitis Externa
Meningitis, Cerebral abscess, dural sinus thrombosis
What is Mastoiditis?
Suppurative infection in the middle ear which spreads to the mastoid air cells
–> inflammation –> bony destruction
Risk factors for Mastoiditis
Immunocompromised
Cholesteatoma
Age 6-13
What is the most common causative organism for Mastoiditis?
Strep pneumoniae
Presentation of Mastoiditis
Intense otalgia, pain behind ear, fever, tender boggy swelling behind ear, external ear protrudes forwards, bulging TM
Conductive deafness
Which type of deafness does Mastoiditis cause?
Conductive
Investigation of Mastoiditis
CT/MRI
Management of Mastoiditis
Broad-spectrum IV antibiotics for 1-2 days then oral
- Cefotaxime/Ceftriaxone
Myringotomy +/- tympanostomy tube
Complications of Mastoiditis
Hearing loss
CN palsies- VI/VII or trigeminal opthalmic
Osteomyelitis
What is a Thyroglossal duct cyst?
Occurs from a persistent epithelial tract from descent of the thyroid from the foramen caecum
Types of Thyroglossal duct cyst
Infrahyoid Suprahyoid Juxtahyoid Intralingual Suprasternal Intralaryngeal
Presentation of Thyroglossal duct cyst
Midline lump in neck, moves on swallowing and tongue protrusion, non-tender
What is the typical age for presentation of Thyroglossal duct cyst?
Age 10 ish
Management of Thyroglossal duct cyst
Surgically removed to diagnose and prevent infection
Causes of Acute Pharyngitis
Influenza, mononucleosis, adenovirus, measles, chicken pox, croup, whooping cough, GpA Strep
What is Acute Pharyngitis?
Inflammation of the oropharynx but not the tonsils
Presentation of Acute Pharyngitis
Pharyngeal exudate, cervical lymphadenopathy, difficulty swallowing, fever, chills, headache
Investigations for Acute Pharyngitis
Throat culture for Strep throat
Which tools can be used to assess the need for antibiotics in Acute Pharyngitis
FeverPAIN/CENTOR
Management of Acute Pharyngitis
Phenoxymethylpenicillin if bacterial
Fluids, paracetamol
What is the typical age of presentation with Epiglottitis?
Age 2-5
Causes of Epiglottitis
Used to be Hib but now vaccine
Strep, Staph aureus, Moraxella catarrhalis, HSV
Reactive epiglottitis to radiotherapy
Presentation of Epiglottitis
Sore throat, odynophagia, drooling, muffled ‘hot potato’ voice, fever
Stridor, respiratory distress
Investigation of Epiglottitis
DO NOT examine airway
Fibre optic laryngoscopy- gold standard
Management of Epiglottitis
DO NOT examine airway
Medical emergency
IV/Oral antibiotics
Intubation/surgical tracheostomy?
Causes of chronic laryngitis
Allergy, asthma, trauma, smoking, sarcoidosis, ACE inhibitors
How long is classified as chronic laryngitis?
> 3 weeks
Presentation of laryngitis
Hoarse/breathy voice, pain/discomfort in neck, URTI symptoms, dysphagia, globus pharyngeus, throat clearing, fever
Management of laryngitis
Acute: mostly self-limiting, voice rest, hydration, antibiotics if fever > 48hrs, purulent sputum, immunocompromised
Chronic: voice therapy, treat underlying condition
What is Quinsy?
Peri-tonsillar abscess, complication of acute tonsillitis, pus between tonsillar capsule and lateral pharyngeal wall
Causative organisms of Peri-tonsillar abscess (Quinsy)
Strep pyogenes, Staph aureus, HiB
Presentation of Peri-tonsillar abscess (Quinsy)
Severe unilateral throat pain, fever, drooling, foul breath, painful swallowing, trismus (lockjaw), earache, unilateral bulging superior and lateral to tonsil
Medial/anterior shift of tonsil + uvula
Management of Peri-tonsillar abscess (Quinsy)
IV Fluids, analgesia
IV antibiotics- eg Ceftriaxone
Surgical aspiraton
What is Ménière’s disease?
Increase in fluid (endolymph) in membranous labyrinth –> endolymphatic hydrops
What is the peak age for Ménière’s disease?
Age 40-60
Risk factors for Ménière’s disease
Allergy, autoimmune conditions, migraine, viral infections
Presentation of Ménière’s disease
- Vertigo
- Tinnitus
- Fluctuating hearing loss
- Sense of aural pressure
Management of Ménière’s disease
- Vertigo- Prochlorperazine
- Prophylaxis- betahistine
- Endolymphatic sac surgery
- DVLA
Patient presents with vertigo, tinnitus, fluctuating hearing loss and a sense of aural pressure, what is the most likely diagnosis?
Ménière’s disease
What is the most common cause of vertigo?
Benign Paroxysmal Positional Vertigo
What is Benign Paroxysmal Positional Vertigo?
Otoliths become detached from macula into semicircular canals
–> hair cells are stimulated
Mostly posterior
Causes of Benign Paroxysmal Positional Vertigo
Idiopathic
Head injury, post-viral infection, complication of surgery
Presentation of Benign Paroxysmal Positional Vertigo
Episodes of vertigo provoked by head movements, attacks sudden onset with rapid resolution once head is kept still
Worse in morning
No hearing loss or tinnitus
Patient presents with episodes of vertigo provoked by head movements and which resolve once head kept still, what is the most likely diagnosis?
Benign Paroxysmal Positional Vertigo
How is Benign Paroxysmal Positional Vertigo diagnosed?
Dix-Hallpike maneouvre
Management of Benign Paroxysmal Positional Vertigo
Usually self-limiting over weeks
Epley maneouvre
DVLA- can drive once symptoms resolved
Surgery last resort
What is the aetiology of Vestibular Neuronitis?
Likely a neuropathy caused by reactivation of latent HSV1 in vestibular ganglion
Presentation of Vestibular Neuronitis
Sudden, spontaneous, severe and incapacitating vertigo, spontaneous nystagmus
NEVER hearing loss or tinnitus
How can you differentiate central from peripheral vertigo?
HINTS examination:
Head impulse
Nystagmus type
Skew
Peripheral: head impulse abnormal, nystagmus unidirectional or absent, no vertical skew
Central: head impulse normal, nystagmus bidirectional, vertical skew
Management of Vestibular Neuronitis
Prochlorperazine/antihistamines for vertigo
Reassurance
Management of Ramsay-Hunt syndrome
Aciclovir + Prednisolone
What is the cause of Ramsay-Hunt syndrome?
Herpes zoster virus
Presentation of Ramsay-Hunt syndrome
Unilateral lower motor neuron facial nerve palsy
Painful and tender vesicular rash in ear canal, pinna and around ear, can extend to anterior 2/3 of tongue and hard palate
Causes of Acute Otitis Media
Viral: RSV, Rhinovirus, Parainfluenza, Influenza
Bacterial: Strep pneumoniae, H influenzae, Moraxella catarrhalis, Strep pyogenes
Which age group is most at risk of Acute Otitis Media
Children as short and more horizontal eustachian tube
Risk factors for Acute Otitis Media
Young, male, smoking (+ passive), contact with other children, GORD, prematurity, immunodeficiency
Presentation of Acute Otitis Media
Inflammation of middle ear
Earache, tugging at ear, fever, irritability, cough, rhinorrhoea
What is found on otoscopy in Acute Otitis Media?
Red/yellow/cloudy TM, bulging TM, perforated TM
Management of Acute Otitis Media
Pain relief
Antibiotics if < 6mths or unwell or no improvement by 72hrs- 5-7 days Amoxicillin
Admission if < 3mths with temp > 38 or systemically unwell
Management of recurrent Acute Otitis Media
Grommets
Prophylactic antibiotics
Complications of Acute Otitis Media
Post-auricular abscess, mastoiditis, meningitis etc
What is the most common cause of hearing impairment in children?
Otitis media with effusion
What is the most common age of presentation with Otitis media with effusion?
Age 2-5
Risk factors for Otitis media with effusion
Cleft palate, Down’s syndrome, Primary Ciliary Dyskinesia, Allergic rhinitis, AOM, Household smoking, Bottle feeding
Presentation of Otitis media with effusion
Hearing loss, foul-smelling aural discharge, recurrent ear infections, mild ear pain, popping sensation
What is seen on otoscopy in Otitis media with effusion?
Abnormal colour of drum, loss of light reflex, air bubbles/air-fluid level, retracted/concaved drum
Management of Otitis media with effusion
Active observation 6-12wks
Hearing aids
Autoinflation
Myringotomy + grommets
What is Cholesteatoma?
3D collection of connective and epidermal tissue in middle ear
–> Bone erosion
Types of Cholesteatoma
- Congenital
- Primary acquired
- Secondary acquired- from trauma to TM
What is the aetiology of Congenital Cholesteatoma?
Squamous epithelium trapped in temporal bone in embryogenesis
Risk factors for Cholesteatoma
Ear trauma, cleft palate, grommets
Presentation of Cholesteatoma
Progressive conductive hearing loss
Erode into structures –> vertigo, headache, facial nerve palsy
Infection –> sigmoid sinus thrombosis, meningitis etc
Grows into auditory canal –> deafness, impaired facial movement
Acquired –> frequent painless foul-smelling otorrhoea
What type of hearing loss does Cholesteatoma cause?
Progressive conductive hearing loss
What is seen on otoscopy in Cholesteatoma?
Pearly white mass behind tympanic membrane
At what age does congenital Cholesteatoma typically present?
6 months - 5 years
What is the gold standard investigation in Cholesteatoma?
CT
Management of Cholesteatoma
Surgery- tympanomastoidectomy/tympanoplasty
Treat infections
Differentials of facial pain
Rhinosinusitis Tension headache Migraine Cluster headache Trigeminal neuralgia TMJ dysfunction Atypical facial pain
How is atypical facial pain managed?
Amitriptylline, Gabapentin, Pregabalin
What is Sinusitis?
Inflammation of the membranous lining of 1 or more sinuses
Name the Paranasal sinuses
- Maxillary
- Sphenoidal
- Frontal
- Ethmoidal
Risk factors for Sinusitis
URTI, asthma, allergy, smoking, DM, immunocompromise
How is acute vs chronic Sinusitis classified?
Acute < 4 weeks
Chronic > 90 days
Most common causative organisms of Acute Sinusitis
Strep pneumoniae, H influenzae, M catarrhalis
Presentation of Acute Sinusitis
Non-resolving cold, pain over sinuses, purulent nasal discharge, reduced sense of smell, headache
Management of Acute Sinusitis
Symptom relief: paracetamol, intranasal decongestant, fluids, nasal saline irrigation
Antibiotics if > 10 days or immunocompromised
- Phenoxymethylpenicillin
Causes of Chronic Sinusitis
Allergic rhinitis, nasal polyps, ciliary dysfunction, immunodeficiency
Presentation of Chronic Sinusitis
Non-resolving cold, pain over sinuses, purulent nasal discharge, reduced sense of smell, headache
Ache on palpation of sinuses
Management of Chronic Sinusitis
Modulate triggers, stop smoking
Nasal steroids
Antibiotics for 3 weeks
What are the criteria for diagnosis of Sinusitis?
- Facial discomfort/pain
- Nasal obstruction/discharge/post-nasal drip
- Decreased or absent sense of smell
What is Trigeminal Neuralgia?
Compression of the trigeminal nerve
Causes of Trigeminal Neuralgia
Compression of trigeminal nerve by…
- Loop of artery or vein
- MS
- Tumours
- AV malformation
Presentation of Trigeminal Neuralgia
Sudden unilateral brief stabbing pain in distribution of 1 or more branches of the trigeminal nerve, electric shocks
What are the common triggers for Trigeminal Neuralgia?
Vibration, skin contact, brushing teeth, oral intake, exposure to wind
Management of Trigeminal Neuralgia
Reassurance
Carbamazepine
Surgery to relieve pressure
Investigationsfor diagnosis of Trigeminal Neuralgia
None- clinical diagnosis
What is the most common site of bleeding in epistaxis?
Anterior- Little’s area- Kiesselbach’s plexus
Causes of epistaxis
Idiopathic
Coagulopathy, rhinitis, trauma, aspirin, warfarin
Investigations in epistaxis
Anterior + posterior rhinoscopy to identify bleeding point
Management of epistaxis
Acute: ABCDE Nasal cautery- silver nitrate Nasal packing- anterior packing Ligation of vessels under GA Angiography + embolisation
What is the temporomandibular joint?
TMJ formed by mandibular condyle inserting into mandibular fossa of the temporal bone
Risk factors for Temporomandibular Joint Disorders
Disc displacement, TMJ hypo/permobility, trauma, bruxism (grinding teeth), stress, anxiety, gout
Presentation of Temporomandibular Joint Disorders
3 cardinal features:
- Facial pain
- Restricted jaw function
- Joint noise
Management of Temporomandibular Joint Disorders
Rest + self care Bite guards Analgesics, NSAIDs, Muscle relaxants IA steroids Surgery
What is the most common type of Pharyngeal cancer?
Squamous cell crcinoma
Risk factors for Pharyngeal cancer
SCC: tobacco, HPV
Nasopharyngeal carcinoma: EBV, heavy alcohol intake
Presentation of Pharyngeal cancer in oropharynx
Persistent sore throat, lump in throat or mouth, ear pain
Presentation of Pharyngeal cancer in hypopharynx
Problems with swallowing, ear pain, hoarseness
Presentation of Pharyngeal cancer in nasopharynx
Lump in neck, nasal obstruction, deafness, post-nasal discharge
2 week wait criteria for Pharyngeal cancer
Unexplained ulceration > 3 weeks
Oral red/white patched
Persistent and unexplained lump in neck
Management of Pharyngeal cancer
External beam radiotherapy main treatment
Surgery, chemo
What is the most common type of Laryngeal cancer?
Almost all Squamous cell carcinoma
Cancer in which areas is classified as Pharyngeal cancer?
Oropharynx/Nasopharynx/Hypopharynx
Cancer in which areas is classified as Laryngeal cancer?
Supraglottis, Glottis, Subglottis
Risk factors for Laryngeal cancer
Smoking, alcohol, asbestos, formaldehyde, nickel, sulphuric acid, HPV16
Which strain of HPV is associated with Laryngeal cancer?
HPV16
Presentation of Laryngeal cancer
Chronic hoarseness, pain, dysphagia, lump in neck, sore throat, earache, persistent cough, breathlessness, haemoptysis
2 week wait criteria for Laryngeal cancer
Persistent unexplained hoarseness
Unexplained lump in neck
Management of Laryngeal cancer
Total/partial laryngectomy, chemo + radiotherapy
What investigation should be done in all people with chronic hoarseness?
Chest x-ray
Which side does Weber’s test localise to in:
i) conductive deafness;
ii) sensorineural deafness?
Conductive deafness- affected side
Sensorineural- unaffected side
In Rinne’s test, if Bone conduction > Air conduction, what type of deafness is present?
Conductive deafness
Aetiology of Branchial cysts
Benign developmental defect in branchial arches
Filled with acellular fluid with cholesterol crystals and encapsulated by stratified squamous epithelium
Lump in neck filled with acellular fluid with cholesterol crystals and encapsulated by stratified squamous epithelium, what is the most likely diagnosis?
Branchial cyst
When do branchial cysts usually present?
Late childhood/early adulthood
How do branchial cysts present?
Painless lateral neck lump, anterior to sternocleidomastoid
Smooth, soft, fluctuant, non-tender, no transillumination
Management of Branchial cyst
Refer to ENT, USS, Fine needle aspiration