Energy? Flashcards
Describe energy storage and demand.
- Organism has energy expenditures: maintenance, repair, growth, activity, thermogenesis
- Organisms has storage of energy: glycogen in liver and muscle and fat in adipose tissue
- If expenditures increase, energy can be taken out of storage
- If activity increases greatly, this may increase the demand
- Increased demand is supplied by eating fats, carbohydrates, proteins, vitamins and minerals
- At rest, principal energy users are the heart, liver and brain
- When active, skeletal muscles are the principle users of energy
How are eating behaviours controlled?
- Energy reserves generate signals of available energy
- Signals to hypothalamus
- Behaviour can be modified to either increase/decrease energy in eating or increase/decrease activity, growth, repair and cellular metabolism
How is brown fat distinguishable from white fat?
Can turn energy into heat
How is intake regulated?
- Satiety centre inhibits the appetite centre.
- Appetite centre stimulates feeding behaviours.
- Modulating input go into both the satiety and appetite regions of the brain.
What stimulates the satiety centre?
- Increased glucose and insulin
- Increased CCK, which correlates to fat content of meal]increased stomach distension
- Increased body fat stores
- Leptin from white fat, proportionate with fat reserves
- Peptide YY/PYY from epithelium of small and large bowel, with a release proportional to the meal size
What inhibits the satiety centre?
- Smell of desirable food
- Sight of desirable food
- Ghrelin from stomach. Levels increase during fasting
What is parabiosis in feeding behaviour?
The anatomical joining of 2 individuals, especially artificially in physiological research. The 2 share a bloodstream.
- When stable, both animals eat normally.
- Electrical lesion of ventromedial nuclei in A
- A becomes obese and B becomes anorexic
- Unkown substance passes form mouse with lesion/A into the blood stream of the normal mouse/B to reduce feeding behaviour, causing B to starve
Feeding/appetite centre in the lateral nucleus – stimulation causes feeding and lesioning causes disinterest in food.
Satiety centre in ventromedial nucleus – stimulation terminates eating and lesioning causes voracious and constant feeding.
How is output regulated?
Eating increases basal metabolic rate and heat production, dietary induced thermogenesis is a process related to secretion, digestion and absorption and uses additional blood supply.
Output/metabolism is measured as oxygen consumption/heat production under eating/basal condition.
With increasing body mass, energy consumption per unit mass and need of food falls. Partly due to heat loss.