Endoscopy Flashcards
What is the incidence of DEATH from EGD?
1 in 10,000 patients (respiratory and cardiac - SEDATION)
Is RECENT MI a relative CONTRAINDICATION to EGD?
YES
What are some of the COMPLICATIONS that can be experienced from endoscopy using UNCLEAN SCOPES?
BACTEREMIA, PHLEBITIS, ASPIRATION PNA, ENDOCARDITIS
Esophageal DILATION and SCLEROTHERAPY carry a higher risk of what COMPLICATION?
BACTEREMIA
Which EGD perocedure carries the HIGHEST RISK for ASPIRATION PNA?
HIGH-VOLUME UGIB
Does ASPIRIN increase the risk of an UGIB during EGD?
NO
How can METHEMOGLOBINEMIA occur during EGD?
ORAL TOPICAL ANESTHESIA
What complication can occur in a patient with ASCITES undergoing esophageal variceal BANDING?
INFECTION of ASCITES
Colon PREPS using MAGNESIUM, SODIUM POHOSPHATE or MANNITOL can cause what issues?
TOXICITY in patients with** RENAL FAILURE** (especially in patients on ACE-I, ARBs and NSAIDs)
MANNITOL or LACTULOSE should NEVER be used for COLON preps, why?
Can cause EXPLOSIONS with ELECTROCAUTERY
What should be CONSIDERED in all patients undergoing endoscopic procedures who have PACEMAKERS and the potential use of ELECTROCAUTERY is there?
GROUNDING PAD AWAY from the HEART and pacemaker should be tuned OFF during procedure
How LONG after a **COLONIC POLYPECTOMY **can there be a procedure-related BLEED?
A FEW WEEKS
HIGHEST RISK of PERFORATION during a COLONOSCOPY occurs after what SURGERY?
HYSTERECTOMY (mostly in rectosigmid or junction of sigmoid and descending)
Colon PERFORATIONS due to AGGRESSIVE INUFFLATION occur where?
CECUM
What is the MISS rate on COLONOSCOPY for polyps >1 cm; < 5 mm?
> 1 cm - 6%
< 5 mm - 27%
Is the RISK of STROKE, MI or PE by stopping anti-thrombotic agents > than the risk of the BLEED that one is trying to manage endoscopcially?
Usually YES
What is an EMERGENCY option for the REMOVAL of the EFFECT of DABIGATRAN (PRADAXA) in a patient with an emergent profuse bleed?
HEMODIALYSIS (or IDARUCIZUMAB, a monoclonal antibody antidote)
What is the REVERSAL AGENT that can be used with APIXABAN (eliquis) and RIVEROXABAN (xarelto)?
ADNEXANET ALFA
What is the REVERSAL AGENT used when anticoagulation is on board with INR >2.5 and endoscopy is needed?
4-FACTOR PROTHROMBIN COMPLEX CONCENTRATE + Vit K or FFP
When is PROTAMINE used as the reversal agent for HEPARIN potentiated BLEED when endoscopy is needed?
LIFE-THREATENING BLEED
In a patient with a RECENTLY-PLACED VASCULAR STENT (< 1 year) or Acute Coronary Syndrome, on ANTICOAGULATION, what is done if ENDOSCOPY is needed?
CONSULTATION with the prescribing service
How should ANTICOAGULATION be RESUMED in a patient after endoscopy with HIGH RISK of REBLEED?
UNFRACTIONATED HEPARIN (short half-life)
What is done with a patient requiring endoscopy and who are on ANTIPLATELET AGENTS (clopidogrel)?
HOLD these until HEMOSTASIS is achieved
For patients with A-FIB associated with VALVULAR DISEASE, MECHANICAL heart valve, LVAD, history of CVA or CHF, CHADSVASC score >2, age >75, prior TIA or CVA, HTN or DM, what is the recommendation for those taking anticoagulation prior to elective ENDOSCOPY?
Use HEPARIN or LMWH BRIDGE (these are HIGH-RISK patients)
For patients with history of DVT, non-valvular A-FIB, BIOPROSTHETIC VALVES, what is recommended for those taking anticoagulation prior to elective ENDOSCOPY?
HOLD meds and RESUME post procedure, NO BRIDGING (LOW-RISK)
In a patient with a DRUG-ELUTING stent, ot a patient on DVT anticoagulation, what is the recommendation for ELECTIVE ENDOSCOPY?
WAIT until anticoagulation period is completed (12 months for the stents)
Do ASPIRIN and NSAIDs need to be stopped for ENDOSCOPIC procedures?
NO
What is the RECOMMENDATION for the THIENOPYRIDINES (clopidogrel, prasugrel and ticagrelor) prior to ENDOSCOPIC procedures?
For HIGH-RISK (of bleeding)procedures, HOLD these for 5-7 DAYS and switch to ASA monotherapy. For LOW-RISK procedures, these may be continued. These may be RESTARTED once endoscopic hemostasis is achieved.
What should be done with a GP IIb/IIIa (eptifibatide, tirofiban) infusion when a patient requires an EMERGENT endoscopic procedure for ACUTE GIB?
DISCONTINUE the infusion (if needed, platelet transfusion or DDAVP may be considered)
When can WARFARIN be restarted after an ENDOSCOPIC procedure?
ON THE SAME DAY if no ongoing bleeding
For RAPIDLY-ACTING (Novel Oral Anti-Coagulants) such as DABIGRATAN, APIXABAN and RIVAROXABAN, WHEN can these agents be restarted after ENDOSCOPIC procedures?
Once ADEQUATE HEMOSTASIS is ensured (no furtheer signs of bleeding) so 12-24 HOURS after and if not use HEPARIN BRIDGE 2-6 HOURS after the procedure. These are ALL RENALLY cleared.
If ANTITHROMBOTIC therapy MUST be restarted after an EMERGENT/URGENT endoscopic procedure, what is the SAFEST WAY to go?
IV UNFRACTIONATED HEPARIN (fast half-life)
HOW do you BRIDGE a patient for an ELECTIVE ENDOSCOPIC procedure with LMWH?
HOLD the WARFARIN for 5 DAYS and CONCOMITANTLY start the LMWH and DISCONTINUE the LMWH 8 HOURS before the procedure.
In which patients can you NOT use LMWH for BRIDGING for ENDOSCOPIC procedures?
PREGNANT WOMEN with MECHANICAL HEART VALVES (thromboses)
Are PROPHYLACTIC antibiotics for ENDOCARDITIS recommended for patients undergoing ENDOSCOPIC procedures?
NO
For WHICH endoscopic procedure is the SUGGESTION of PROPHYLACTIC antibiotics against ENDOCARDITIS, REASONABLE?
ERCP when CHOLANGITIS (E. coli) is suspected and HIGH-RISK patient (prosthetic heart valve, heart transplant, history of previous infectious endocarditis, and congenital heart conditions pre/post repair)