Endometriosis and Amenorrhea Flashcards
Define endometriosis
A disorder in which tissue that normally lines the uterus grows outside the uterus
a definitive diagnosis of endometriosis requires what?
surgical visualization (laparscopy)
a surgery that uses a thin, lighted tube put through a cut (incision) in the belly to look at the abdominal organs or the female pelvic organs
laparascopy
what is the main complaint in the clinical presentation of endometriosis?
pelvic pain
dyspareunia
painful intercourse
dysmenorrhea
painful menstruation, typically involving abdominal cramps.
most common cause of secondary dysmenorrhea
endometriosis
endometriosis is accompanied by what percentage of infertility?
30-50%
the incidence of endometriosis occurs in what % of women of child bearing age?
6-10%
can endometriosis occur prior to menarche?
yes
how does genetic predisposition play a role in endometriosis?
6-fold greater if a mother or sister has disease
when the womb lining (endometrium) flows backwards through the fallopian tubes and into the abdomen (tummy) instead of leaving the body as a period. This tissue then embeds itself on the organs of the pelvis and grows.
retrograde menstration
what are the 3 ideas for the etiology of endometriosis?
retrograde menstruation, vasular/lymphatic spread, and immunological disorder
describe how endometriosis is thought to be an immunologic disorder
it is when there is a failure to clear retrograde menstral flow, because retrograde flow is thought to be fairly common but doesn’t elicit endometriosis in most women
lesions are usually restricted to what areas?
within the pelvic cavity such as ovaries, fallopian tubes, outside uterus, intestines, bladder, and ureters
lesions generate local inflammation and can be more painful during menstruation why?
because they respond to estrogen and progesterone
how do you eliminate the problem of endomteriosis entirely?
ovarectomy +/- hysterectomy
what yields the best results in reduction of pain?
surgical excision
what is the primary chose for restoring fertility when it’s loss is due to endometriosis?
surgical excision
GOT for endometriosis?
pain reduction
what are the 2 first choice drugs for endometriosis?
NSAIDs or CHC’s
do NSAID’s of CHC’s help with lesion eradication or fertility?
no, just help pain
how to Tx pain of endometriosis but maintain fertility (if it’s there)?
NSADs
what do progestins do?
establish anovularoty state with amenorrhea
