Endometrial Carcinoma

Question 1

What is heredity condition for development of endometrial cariconoma?

Answer 1

1.HNPCC
2.COwden syndrome

Question 2

Condition where oestrogen is excess

Answer 2

1.chronic endometrial hyperplasia
2.in postmenpausal years
3.women have estrogen secreting tumours and prolonged estrogen therapy
4.women with breast cancer and taking tamoxifen
5.

Question 3

Other risk factors

Answer 3

1.DM
2.Obesity
3.HT
4.nulliparous

Question 4

Pathogenisi of endometrial caricinoma

Answer 4

1.TYPE1
-predominant 80-85
-oestrogen dependant
-related to endometrial hyperplasia
-morphology type:endometroid and mucinous
4.common mutation of kras