Endometrial cancer Flashcards
1
Q
give two protective factors for endometrial carcinoma
A
COCP
pregnancy
2
Q
give some risk factors for endometrial carcinoma
A
endogenous oestrogen excess (PCOS, obesity, nulliparity, early menopause)
exogenous oestrogen excess (unopposed oestrogen therapy, tamoxifen)
Misc: diabetes, Lynch type II syndrome
3
Q
how does endometrial carcinoma present
A
post- menopausal bleeding is most common symptom
pre-menopausal patients have IMB or irregular bleeding
4
Q
what is the definitive management of endometrial carcinoma
A
total laparoscopic hysterectomy with bilateral salpingo-oophorectomy
5
Q
what pathology is seen in 90% of endometrial cancers
A
> 90% adenocarcinoma