endomembrane system & bulk transport processes Flashcards

1
Q

endomembrane system

A

membrane system interconnected by direct physical contact/transfer by vesicles

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2
Q

what is endomembrane system comprised of

A

nuclear envelope, endoplasmic reticulum (ER), Golgi apparatus, vesicles, lysosomes, vacuoles, plasma membrane

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3
Q

endoplasmic reticulum (ER)

A

inside the cytoplasm, comprised of 2 regions; smooth ER sER & rough ER rER

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4
Q

sER main function

A

involved in metabolising carbohydrates, synthesising lipids for membrane detoxifying drugs & poison, storage of calcium ions

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5
Q

rER functions

A

involved in protein synthesis, rough appearance due to ribosomes,

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6
Q

Golgi complex structure

A

series of membrane sacs & associated vesicles

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7
Q

Golgi complex function

A

receives, modifies, sorts and ships proteins arriving from rER

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8
Q

Golgi complex polarity

A

has cis-trans faces

  • vesicles from endoplasmic reticulum arrive at cis face
  • processed vesicles leave via trans face, facing plasma membrane
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9
Q

Golgi complex, glycosylation function

A

addition/modification of carbohydrates to proteins - determining function of protein

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10
Q

Golgi complex, sorting protein function

A

adds molecular markers that direct proteins to correct vesicles before ‘budding’ from trans face

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11
Q

Golgi complex, directing vesicle trafficking function

A

adds molecular ‘tags’ to vesicles leaving the trans face, directing them to correct targets/locations

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12
Q

vesicles

A

membrane bound (lipid bilayer), cytoplasm/fluid filled organelles

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13
Q

transport vesicle function

A

moving things round the cell
eg. ER —> golgi

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14
Q

secretory vesicle function

A

moving to plasma membrane to fuse w it and release contents

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15
Q

vacuole function

A

vesicle structure of plant cells

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16
Q

exocytosis

A

process of transporting material (glycoproteins) to cell surface or out of cell

17
Q

constitutive exocytosis

A

release extracellular matrix proteins

18
Q

regulated exocytosis

A

controlled, signal is needed in order for hormones & neurotransmitters to be released

19
Q

endocytosis

A

cell takes in molecules and particular matter at cell membrane

20
Q

endo - phagocytosis

A

cell “eating” , uptake of food particles

21
Q

endo - pinocytosis

A

cell “drinking”, uptake of extracellular fluid containing various solutes eg proteins & sugars

uptake is non-selective, no control of what ends up in created vesicle

22
Q

endo - receptor-mediated endo

A

form of pinocytosis, allowing cell to take up bulk quantities of specific substances that may be present at only low concs in extracellular fluid

receptor proteins used to selectively capture and bind to required solute

23
Q

lysosome

A

membrane-bound organelles made by rER & Golgi body containing hydrolytic enzymes
has acidic interior for enzymes to be active

24
Q

lysosome function

A

phagolytic (eating) vacuoles fuse with lysosomes in order to degrade proteins, lipids, carbohydrates and nucleic acids, and release these breakdown products into cell

25
Q

autophagy

A

important for cell health, as it digests & recycles unwanted cellular material.

lysosomes do this