endomembrane system & bulk transport processes Flashcards
endomembrane system
membrane system interconnected by direct physical contact/transfer by vesicles
what is endomembrane system comprised of
nuclear envelope, endoplasmic reticulum (ER), Golgi apparatus, vesicles, lysosomes, vacuoles, plasma membrane
endoplasmic reticulum (ER)
inside the cytoplasm, comprised of 2 regions; smooth ER sER & rough ER rER
sER main function
involved in metabolising carbohydrates, synthesising lipids for membrane detoxifying drugs & poison, storage of calcium ions
rER functions
involved in protein synthesis, rough appearance due to ribosomes,
Golgi complex structure
series of membrane sacs & associated vesicles
Golgi complex function
receives, modifies, sorts and ships proteins arriving from rER
Golgi complex polarity
has cis-trans faces
- vesicles from endoplasmic reticulum arrive at cis face
- processed vesicles leave via trans face, facing plasma membrane
Golgi complex, glycosylation function
addition/modification of carbohydrates to proteins - determining function of protein
Golgi complex, sorting protein function
adds molecular markers that direct proteins to correct vesicles before ‘budding’ from trans face
Golgi complex, directing vesicle trafficking function
adds molecular ‘tags’ to vesicles leaving the trans face, directing them to correct targets/locations
vesicles
membrane bound (lipid bilayer), cytoplasm/fluid filled organelles
transport vesicle function
moving things round the cell
eg. ER —> golgi
secretory vesicle function
moving to plasma membrane to fuse w it and release contents
vacuole function
vesicle structure of plant cells
exocytosis
process of transporting material (glycoproteins) to cell surface or out of cell
constitutive exocytosis
release extracellular matrix proteins
regulated exocytosis
controlled, signal is needed in order for hormones & neurotransmitters to be released
endocytosis
cell takes in molecules and particular matter at cell membrane
endo - phagocytosis
cell “eating” , uptake of food particles
endo - pinocytosis
cell “drinking”, uptake of extracellular fluid containing various solutes eg proteins & sugars
uptake is non-selective, no control of what ends up in created vesicle
endo - receptor-mediated endo
form of pinocytosis, allowing cell to take up bulk quantities of specific substances that may be present at only low concs in extracellular fluid
receptor proteins used to selectively capture and bind to required solute
lysosome
membrane-bound organelles made by rER & Golgi body containing hydrolytic enzymes
has acidic interior for enzymes to be active
lysosome function
phagolytic (eating) vacuoles fuse with lysosomes in order to degrade proteins, lipids, carbohydrates and nucleic acids, and release these breakdown products into cell