endogenous pacemakers +sleep wake Flashcards
The suprachiasmatic nucleus
tiny bundle of nerve cells located in hypothalamus in each hemisphere of the brain
- one of the primary endogenous pacemakers in mammals
THE SCN coNNECTION TO OPTIC
nerve fibres connected to the eye in an area called the optic chiasm - it received information about light directly
Decoursey
destroyed the SCN connections in the brain of 30 chipmunks who were then returned to their natural habitat and observed for 80 days - the sleep wake cycle of the chipmunks disappeared and by the end of the study, a significant proportion of them had been killed by predators (because they were active when they should have been sleeping)
RALPH
bred mutant hamsters with a 20 hour sleep wake cycle - when SCN cells from the foetal tissue of mutant hamsters wee transplanted into the brains of normal hamsters, the cycles of the second group defaulted to 20 hours
-animal studies
cannot be generalised
-ethical concerns
harm to the animals
-affected natural habitat