endogenous pacemakers +sleep wake Flashcards

1
Q

The suprachiasmatic nucleus

A

tiny bundle of nerve cells located in hypothalamus in each hemisphere of the brain
- one of the primary endogenous pacemakers in mammals

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2
Q
A
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3
Q

THE SCN coNNECTION TO OPTIC

A

nerve fibres connected to the eye in an area called the optic chiasm - it received information about light directly

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4
Q

Decoursey

A

destroyed the SCN connections in the brain of 30 chipmunks who were then returned to their natural habitat and observed for 80 days - the sleep wake cycle of the chipmunks disappeared and by the end of the study, a significant proportion of them had been killed by predators (because they were active when they should have been sleeping)

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5
Q

RALPH

A

bred mutant hamsters with a 20 hour sleep wake cycle - when SCN cells from the foetal tissue of mutant hamsters wee transplanted into the brains of normal hamsters, the cycles of the second group defaulted to 20 hours

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6
Q

-animal studies

A

cannot be generalised

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7
Q

-ethical concerns

A

harm to the animals
-affected natural habitat

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