EndoCRYYYYYne Flashcards
Prednisone
synthetic GCC, pretty much fake cortisol anti-inflam, immune suppression, adrenocortial insufficiency - GCC excess
Fludrocortisone
Fake mineralcorticoid aldosterone mimic
Cosyntropin
ACTH faker use the diagnose adrenal insufficency
Beclomethsone
Synthetic GCC anti-inflam used for ASTHMA AND ALLERGIC RHINITIS
Estrogen
estrogen! inhibit FSh and LH to decrease ovulation OCP - Endometrial Ca, Breast CA, TEE
Diethylstilbestrol–DES
pseudo estrogen sucks: vaginal and cervical clear cell adenocarcinoma
Clomiphene
SERM Antagonist at hypothalamus: increase GnRH/FSH/LH Agonist at ovaries Rx: infertility -: too many babies!
Tamoxifen
SERM Antagonist for boobies! Agonist for bone. Breast cancer drug - Hot flash, endometrial cancer, VTEE
Raloxifene
SERM he does what tamoxifen does without the endometrial cancer risk
Anastrozole
inhibitor of aromatse Androgen stopper treat ER positive Breast CA - Arthralgias, myalgias
Progestin
Pseudo Progesterone rx: contraception prevent endometrial maturation, decrease uterine and tubal motility HRT DUB–stop bleed due to constant estrogen without progesterone Endometriosis–prevent proliferation of ectopic endometrial tissue
Testosterone
Testosterone make you a man! rx: hypogonad -: acne and being michael phelps
Flutamide
Anti-androgen competitive antagonist for androgen receptor rx: prorstate cancer
Finasteride
5a reductase inhibtor block conversion of T–>DHT rx: BPH and balding
Leuprolide
Fake GnRH intermittently: stimulate FSh and LH contiuously (on loop) inhibit FSH and LH RX: infertility and prostate cancer