Endocrinology Conditions

Question 1

Describe the common presentation of hyperthyroidism.

Answer 1

• Heat intolerance
• Weight loss
• Lid lag
• Goitre
• Thinning hair
• Thyroid eye disease (exopthalamus, periorbital oedema, diplopia)

Question 2

Describe the WHO grading system for goitres.

Answer 2

Stage 0-III:

0) Not visible/palpable
I) Palpable (or stage Ib is visible when neck extended)
II) Goitre visible at any position of neck
III) Goitre visible from distance

Question 3

Which TWO pharmacological therapies can be used for the treatment of hyperthyroidism.

Answer 3

• Carbimazole

- Polypropyluracil

Question 4

What is the difference between primary and secondary hyperthyroidism.

Answer 4

Primary hyperthyroidism is where there is an issue at the level of the thyroid where it is realeasing large amounts of thyroid hormone (T3/T4). This is in contrast to secondary hyperthyroidism where the inappropriate levels of thyroid hormone expression occur due to an issue at the level of the pituitary. (TSH levels high)