Endocrinology Flashcards
Factors contributing to Hyperglycemia?
- Reduced insulin secretion
- Decreased glucose usage
- Increased glucose production
It is the leading cause of end stage renal disease, non traumatic lower extremity amputations and adult blindness
Diabetes Mellitus
Results in Autoimmunity against the insulin producing beta cells wgich results to complete or near total insulin deficiency
Type 1 diabetes Mellitus
Heterogenous group with variable degrees of insulin resistance, impaired insulin production and increase hepatic glucose production
Type 2 diabetes mellitus
Maturity onset diabetes of the Young and Monegenic diabetes are?
- Autosomal Dominant
- Usually <25year old sometimes in neonatal period
- Impaired Insulin Secretion
Islets are damaged by a primarily by pathologic process originating in the pancreatic exocrine tissue
DM resulting from cyctic fibrosis or chronic pancreatitis
What are endocrinopathies involving hormones that antagonize insulin function?
Acromegaly or Cushing’s disease
Acute onset of T1DM that may be related to viral infection of islets?
Fulminant Diabetes Mellitus
In gestational DM, glucose intolerance develop in what trimesters?
2nd - 3rd trimesters